Zobrazeno 1 - 10
of 1 266
pro vyhledávání: '"M, Glazer"'
Autor:
Matthew J. O’Neill, Tao Yang, Julie Laudeman, Maria E. Calandranis, M. Lorena Harvey, Joseph F. Solus, Dan M. Roden, Andrew M. Glazer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Interpreting the clinical significance of putative splice-altering variants outside canonical splice sites remains difficult without time-intensive experimental studies. To address this, we introduce Parallel Splice Effect Sequencing (ParSE-
Externí odkaz:
https://doaj.org/article/8f555e7c501b489da69369ad216d2e01
Autor:
Ayesha Muhammad, Maria E. Calandranis, Bian Li, Tao Yang, Daniel J. Blackwell, M. Lorena Harvey, Jeremy E. Smith, Zerubabell A. Daniel, Ashli E. Chew, John A. Capra, Kenneth A. Matreyek, Douglas M. Fowler, Dan M. Roden, Andrew M. Glazer
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background KCNE1 encodes a 129-residue cardiac potassium channel (I Ks) subunit. KCNE1 variants are associated with long QT syndrome and atrial fibrillation. However, most variants have insufficient evidence of clinical consequences and thus
Externí odkaz:
https://doaj.org/article/b05f643c1f884a7dbcf19bfac871b67b
Autor:
Melina Claussnitzer, Victoria N. Parikh, Alex H. Wagner, Jeremy A. Arbesfeld, Carol J. Bult, Helen V. Firth, Lara A. Muffley, Alex N. Nguyen Ba, Kevin Riehle, Frederick P. Roth, Daniel Tabet, Benedetta Bolognesi, Andrew M. Glazer, Alan F. Rubin
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Multiplexed assays of variant effect (MAVEs) have emerged as a powerful approach for interrogating thousands of genetic variants in a single experiment. The flexibility and widespread adoption of these techniques across diverse disciplines h
Externí odkaz:
https://doaj.org/article/ee5b2abbc9bf4533aed98196fa9861b1
Autor:
Zoe Fraade-Blanar, Aaron M. Glazer
Fandom isn't a noun, it's a verb. Fans create; they engage; they discuss. From comics to clothing, boundaries between fans and creators are blurring, and in this new fandom-based economy, it's clear: consumers may buy a product, but it is fans who ca
Autor:
Rachael Putman, Adele S. Ricciardi, Kelly E. W. Carufe, Elias Quijano, Raman Bahal, Peter M. Glazer, W. Mark Saltzman
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Through preimplantation genetic diagnosis, genetic diseases can be detected during the early stages of embryogenesis, but effective treatments for many of these disorders are lacking. Gene editing could allow for correction of the underlying
Externí odkaz:
https://doaj.org/article/3edcc4c4f2cd451898388383fe6988a7
Autor:
A. M. Glazer, Patience Thomson
Crystal Clear takes you behind the scenes in the life of one of the most prominent scientists of the twentieth century, William Lawrence Bragg (WLB) - an innovative genius, who together with his father, William Henry Bragg (WHB) founded and developed
Autor:
Yong-Li Dong, Gangadhara P. Vadla, Jin-Yu (Jim) Lu, Vakil Ahmad, Thomas J. Klein, Lu-Fang Liu, Peter M. Glazer, Tian Xu, Chiswili-Yves Chabu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Dong, Vadla et al. find that oncogenic Ras and p53 cooperatively stimulate JAK/STAT cytokines to promote non-autonomous tissue overgrowth in Drosophila. Further, blocking STAT signalling prevents the growth-inducing effect of p53 overexpression and i
Externí odkaz:
https://doaj.org/article/eca0121cdb5c4fb8ac2dfcc338fcb5ed
Autor:
Lawrence M. Glazer
Few people today remember John Swainson. As a teenage soldier he lost both legs in a WWII landmine explosion. Back in the United States, following a meteoric political rise in the Michigan State Senate, Swainson was elected as Michigan's youngest gov
Autor:
Chris M. Cassara, Micah T. Long, John T. Dollerschell, Floria Chae, David J. Hall, Gozde Demiralp, Matthew J. Stampfl, Brittney Bernardoni, Daniel P. McCarthy, Joshua M. Glazer
Publikováno v:
Medicina, Vol 58, Iss 12, p 1815 (2022)
The rates of survival with functional recovery for out of hospital cardiac arrest remain unacceptably low. Extracorporeal cardiopulmonary resuscitation (ECPR) quickly resolves the low-flow state of conventional cardiopulmonary resuscitation (CCPR) pr
Externí odkaz:
https://doaj.org/article/50ebb38b28794a26b78e430997f05ae3
Publikováno v:
APL Materials, Vol 9, Iss 3, Pp 030702-030702-8 (2021)
PbZrO3-based antiferroelectric crystals are of great interest in both fundamental and applied research, not only because of the antiferroelectric feature at room temperature but also because of the existence of a peculiar intermediate state at ele
Externí odkaz:
https://doaj.org/article/18f956ba8f6f4272a0ca0e75194dfc86