Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M, Giancarlo"'
Autor:
V.A. Myasoedova, M. Chiesa, N. Cosentino, V. Valerio, D. Moschetta, I. Massaiu, M. Bozzi, M. Giancarlo, P. Poggio
Publikováno v:
Atherosclerosis. 355:30
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Biopharmaceutics & Drug Disposition. 24:87-94
Biotransformation of gepirone to 1-(2-pyrimidinyl)-piperazine (1-PP) and 3'-OH-gepirone, as well as two other hydroxylated metabolites, was studied in vitro using a human liver microsomal preparation and heterologously expressed human CYP3A4 and CYP2
Autor:
Gina M. Giancarlo, Brian W. Granda, Lisa L. von Moltke, Karthik Venkatakrishnan, David J. Greenblatt
Publikováno v:
European Journal of Clinical Pharmacology. 57:31-36
Objectives: To determine the relative contribution of cytochromes P450 (CYP) 2C9 and 2C19 to the formation of 5-(-4-hydroxyphenyl)-5-phenylhydantion (HPPH) from phenytoin (PPH). Design: Hydroxylation of PPH to form HPPH was studied in vitro using hum
Autor:
Brian W. Granda, David J. Greenblatt, Gina M. Giancarlo, Lisa L. von Moltke, Richard I. Shader
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:385-388
Zafirlukast is a cysteinyl leukotriene antagonist used to treat allergic and exercise-induced asthma. This in vitro study used human liver microsomes to evaluate the inhibitory activity of zafirlukast versus six human cytochrome P450 (CYP) isoforms.
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(8)
Transformation of escitalopram (S-CT), the pharmacologically active S-enantiometer of citalopram, to S-desmethyl-CT (S-DCT), and of S-DCT to S-didesmethyl-CT (S-DDCT), was studied in human liver microsomes and in expressed cytochromes (CYPs). Biotran
Autor:
Gina M. Giancarlo, Richard I. Shader, Johanna P. Daily, David J. Greenblatt, Lisa L. von Moltke, Su Xiang Duan, Brian W. Granda, Jerold S. Harmatz
Publikováno v:
Journal of clinical pharmacology. 41(1)
The capacity of three clinically available nonnucleoside reverse transcriptase inhibitors (NNRTIs) to inhibit the activity of human cytochromes P450 (CYPs) was studied in vitro using human liver microsomes. Delavirdine, nevirapine, and efavirenz prod
Publikováno v:
Biopharmaceuticsdrug disposition. 20(8)
Zafirlukast is a cysteinyl leukotriene antagonist used to treat allergic and exercise-induced asthma. This in vitro study used human liver microsomes to evaluate the inhibitory activity of zafirlukast versus six human cytochrome P450 (CYP) isoforms.
Publikováno v:
Journal of pharmacological and toxicological methods. 40(4)
A method has been developed to quantify ritonavir concentrations in human plasma and in mouse serum, liver, and brain using high-performance liquid chromatography. Extraction recoveries for ritonavir and its internal standard averaged greater than 95
Autor:
N, Giordano, M, Senesi, S, Gonnelli, C, Cepollaro, F, Palumbo, G, Mattii, C, Gennari, T, Conti, V, Acquafredda, G, Nicola, S, Marco, G, Stefano, C, Chiara, P, Francesco, M, Giancarlo, G, Carlo, C, Tullio, A, Vincenzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::69f2745b5b21fc3af63d45db9aa46a19
http://hdl.handle.net/11365/42313
http://hdl.handle.net/11365/42313