Zobrazeno 1 - 10
of 155
pro vyhledávání: '"M, Gazdag"'
Autor:
Kristina Friedel, Monika A. Popp, Julian C. J. Matern, Emerich M. Gazdag, Ilka V. Thiel, Gerrit Volkmann, Wulf Blankenfeldt, Henning D. Mootz
Publikováno v:
Chemical Science
Steric bulk can compensate for a catalytically critical histidine in an intein's active site and promote the N–S acyl shift.
Inteins remove themselves from a precursor protein by protein splicing. Due to the concomitant structural changes of t
Inteins remove themselves from a precursor protein by protein splicing. Due to the concomitant structural changes of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14384406f970557b02759cb6e411a35e
https://hdl.handle.net/10033/621664
https://hdl.handle.net/10033/621664
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 54:458-462
In the pharmaceutical industry fast and efficient separation techniques play an increasing role among analytical methods because the samples to be investigated grow both in complexity and number, and there is an increasing time pressure to complete t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7103c861eaac99c8564de948fc776c7a
https://doi.org/10.1016/j.jpba.2010.09.012
https://doi.org/10.1016/j.jpba.2010.09.012
Publikováno v:
Chromatographia. 71:35-42
Temperature dependence (10–50 °C) of the chiral LC separation of norgestrel was studied using native CDs added to a methanol–water 1:1 eluent. α- or β-CDs gave no enantiodiscrimination, while baseline LC separation was achieved with γ-CD. 1H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51405077586a6ba07254acda02e118dd
https://doi.org/10.1365/s10337-010-1511-3
https://doi.org/10.1365/s10337-010-1511-3
Autor:
M. Gazdag, Imre Klebovich
Publikováno v:
Chromatographia. 68:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f277605f6d9f6e1472453ec05c38a5
https://doi.org/10.1365/s10337-008-0867-0
https://doi.org/10.1365/s10337-008-0867-0
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 29:1153-1157
The impurity profile of ethynodiol diacetate was investigated using the HPLC/UV/MS method. Using the slightly modified HPLC method of USP 24 two impurities, earlier isolated by preparative HPLC and investigated by NMR spectroscopy were separated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50636081a61c8de18cd2597a2ec315d9
https://doi.org/10.1016/s0731-7085(02)00165-6
https://doi.org/10.1016/s0731-7085(02)00165-6
Autor:
Anna Laukó, Peter Horvath, Sándor Görög, Katalin Varga, G. Balogh, J. Brlik, Mónika Babják, M. Gazdag, F. Dravecz
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 18:511-525
Due to the varied reactions leading to the 3-oxo group in steroids and the reactivity of its environment, a large number of impurities related to this group are formed during the reaction steps and the degradation studies. In this paper the experienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f02d718a861d59299d26f84e627da25
https://doi.org/10.1016/s0731-7085(98)00206-4
https://doi.org/10.1016/s0731-7085(98)00206-4
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 17:1029-1036
Reversed-phase HPLC methods using C-18 and C-8 columns as well as various isocratic and gradient systems with aqueous ammonium acetate, methanol and acetonitrile are described for the separation of the impurities of mazipredone (11beta,17-dihydroxy-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f56c6821d94e022c9bda7a49330881
https://doi.org/10.1016/s0731-7085(98)00068-5
https://doi.org/10.1016/s0731-7085(98)00068-5
Publikováno v:
Analytica Chimica Acta. 352:231-237
Reversed phase HPLC methods have been developed for the separation of related peptides from two synthetic thymopoietin fragments: thymotrinan (Arg-Lys-Asp) and thymocartin (Arg-Lys-Asp-Val), as experimental immunostimulant drugs. The optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f416030ef4141b81e5c88a2ba6319e42
https://doi.org/10.1016/s0003-2670(97)00119-0
https://doi.org/10.1016/s0003-2670(97)00119-0
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 14:1115-1124
4-Ene-3-ketosteroids and 17-ketosteroids were quantitatively transformed into the corresponding hydrazones using Girard P and T reagents, respectively. The positively charged derivatives were separated by capillary electrophoresis. The spectrophotome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc01479f96913ade9196b6ea2725d27c
https://doi.org/10.1016/0731-7085(95)01693-7
https://doi.org/10.1016/0731-7085(95)01693-7
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 659:51-84
Derivatization reactions aimed at creating the basis for the chromatographic resolution of biologically and pharmaceutically important enantiomers are reviewed, with emphasis on the literature published in the last 10 years. Three main aspects of chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e62bbe16e1a5341bf0c0eac313f0c6
https://doi.org/10.1016/0378-4347(94)00124-3
https://doi.org/10.1016/0378-4347(94)00124-3