Zobrazeno 1 - 10
of 1 879
pro vyhledávání: '"M, Gahr"'
Autor:
Sebastian Deichsel, Lisa Frankenreiter, Johannes Fechner, Bernd M Gahr, Mirjam Zimmermann, Helena Mastel, Irina Preis, Anette Preiss, Anja C Nagel
Publikováno v:
eLife, Vol 12 (2024)
Notch signalling activity regulates hematopoiesis in Drosophila and vertebrates alike. Parasitoid wasp infestation of Drosophila larvae, however, requires a timely downregulation of Notch activity to allow the formation of encapsulation-active blood
Externí odkaz:
https://doaj.org/article/fdcd8159915742a1a89e5fbf9887bf14
Publikováno v:
Cells, Vol 13, Iss 7, p 576 (2024)
Blood cells in Drosophila serve primarily innate immune responses. Various stressors influence blood cell homeostasis regarding both numbers and the proportion of blood cell types. The principle molecular mechanisms governing hematopoiesis are conser
Externí odkaz:
https://doaj.org/article/e1fd3c4944bc4f37a55079230916b087
Publikováno v:
European Psychiatry, Vol 66, Pp S305-S305 (2023)
Introduction Drug-Induced Liver Injury (DILI) is one of the most common causes of hospitalization due to liver failure and represents a considerable challenge in clinical practice. One risk factor is the long-term use of a drug. Antipsychotics are re
Externí odkaz:
https://doaj.org/article/57656863bbef49daa9c17dbad6b615f4
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112034- (2023)
Summary: The categorization of animal vocalizations into distinct behaviorally relevant groups for communication is an essential operation that must be performed by the auditory system. This auditory object recognition is a difficult task that requir
Externí odkaz:
https://doaj.org/article/21725a3044e8484bbf6a7b85a22d97c4
Publikováno v:
European Psychiatry, Vol 65, Pp S279-S280 (2022)
Introduction Sexual dysfunction is a frequent adverse drug reaction (ADR) of antidepressants that considerably affects quality of life and adherence to therapy. We previously investigated the potential underlying neurofunctional mechanisms by neuroim
Externí odkaz:
https://doaj.org/article/ec9e3049922045c1b0b60b0d345fef9e
Autor:
T. Kregel, C. Schönfeldt-Lecuona, A. Schmidt, J. Kassubek, J. Dreyhaupt, R. Freudenmann, B. Connemann, M. Gahr, E. Pinkhardt
Publikováno v:
European Psychiatry, Vol 65, Pp S76-S76 (2022)
Introduction Volume reductions in brain structures of patients with schizophrenia spectrum disorder (SSD) have repeatedly been found in voxel-based morphometry MRI studies. Hence, an underlying neurodegenerative etiological component of SSD is curre
Externí odkaz:
https://doaj.org/article/f80da054a30f48ea8296f1fbdd4f75b5
Publikováno v:
European Psychiatry, Vol 65, Pp S730-S730 (2022)
Introduction Drug-induced liver injury is one of the leading causes for acute liver failure and drug withdrawal after marketing approval. One important risk factor is the extent of exposure of the hepatocytes to a substance, either by high doses or b
Externí odkaz:
https://doaj.org/article/309d8505a2ba42eeac56747e0964a40a
Autor:
Anja Bühler, Bernd M. Gahr, Deung-Dae Park, Alberto Bertozzi, Alena Boos, Mohankrishna Dalvoy, Alexander Pott, Franz Oswald, Rhett A. Kovall, Bernhard Kühn, Gilbert Weidinger, Wolfgang Rottbauer, Steffen Just
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
In contrast to mammals, the zebrafish maintains its cardiomyocyte proliferation capacity throughout adulthood. However, neither the molecular mechanisms that orchestrate the proliferation of cardiomyocytes during developmental heart growth nor in the
Externí odkaz:
https://doaj.org/article/96001da5e7a44875bca991c5371b18cb
Autor:
Lisa Frankenreiter, Bernd M. Gahr, Hannes Schmid, Mirjam Zimmermann, Sebastian Deichsel, Philipp Hoffmeister, Aleksandra Turkiewicz, Tilman Borggrefe, Franz Oswald, Anja C. Nagel
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The highly conserved Notch signaling pathway controls a multitude of developmental processes including hematopoiesis. Here, we provide evidence for a novel mechanism of tissue-specific Notch regulation involving phosphorylation of CSL transcription f
Externí odkaz:
https://doaj.org/article/1dc96dd13eb84d14a5b10673ca6bc5a5
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