Zobrazeno 1 - 10
of 1 168
pro vyhledávání: '"M, Fujihara"'
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XL-7/W3, Pp 403-408 (2015)
Vegetation and land cover in Japan are rapidly changing. Abandoned farmland in 2010, for example, was 396,000 ha, or triple that of 1985. Efficient monitoring of changes in land cover is vital to both conservation of biodiversity and sustainable regi
Externí odkaz:
https://doaj.org/article/8ae8d5df01f84874a9a992d8e2326d6c
Autor:
Sophia Ceder, Sofi E. Eriksson, Ying Yu Liang, Emarndeena H. Cheteh, Si Min Zhang, Kenji M. Fujihara, Julie Bianchi, Vladimir J. N. Bykov, Lars Abrahmsen, Nicholas J. Clemons, Pär Nordlund, Sean G. Rudd, Klas G. Wiman
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-10 (2021)
Abstract Asparaginase depletes extracellular asparagine in the blood and is an important treatment for acute lymphoblastic leukemia (ALL) due to asparagine auxotrophy of ALL blasts. Unfortunately, resistance occurs and has been linked to expression o
Externí odkaz:
https://doaj.org/article/b2b5eed6ca834936815c57813c137b8e
Autor:
Julia V. Milne, Bonnie Z. Zhang, Kenji M. Fujihara, Swati Dawar, Wayne A. Phillips, Nicholas J. Clemons
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The prevalence and dire implications of mutations in the tumour suppressor, p53, highlight its appeal as a chemotherapeutic target. We recently showed that impairing cellular antioxidant systems via inhibition of SLC7A11, a component of the
Externí odkaz:
https://doaj.org/article/ba9b4fb88cd4428c8a2cf11039b060f4
Autor:
Jovana R. Gotovac, Tanjina Kader, Julia V. Milne, Kenji M. Fujihara, Luis E. Lara-Gonzalez, Kylie L. Gorringe, Sangeetha N. Kalimuthu, Madawa W. Jayawardana, Cuong P. Duong, Wayne A. Phillips, Nicholas J. Clemons
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 689-713 (2021)
Background & Aims: Esophageal adenocarcinoma (EAC) develops from its precursor Barrett’s esophagus through intermediate stages of low- and high-grade dysplasia. However, knowledge of genetic drivers and molecular mechanisms implicated in disease pr
Externí odkaz:
https://doaj.org/article/a7e5902c1bfa452b8729ab028422f939
Autor:
Sophia Ceder, Sofi E Eriksson, Emarndeena H Cheteh, Swati Dawar, Mariana Corrales Benitez, Vladimir J N Bykov, Kenji M Fujihara, Mélodie Grandin, Xiaodun Li, Susanne Ramm, Corina Behrenbruch, Kaylene J Simpson, Frédéric Hollande, Lars Abrahmsen, Nicholas J Clemons, Klas G Wiman
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-20 (2020)
Abstract The tumor suppressor gene TP53 is the most frequently mutated gene in cancer. The compound APR‐246 (PRIMA‐1Met/Eprenetapopt) is converted to methylene quinuclidinone (MQ) that targets mutant p53 protein and perturbs cellular antioxidant
Externí odkaz:
https://doaj.org/article/ad163b956af24ac198adeee8afcb4f6a
Autor:
Sophia Ceder, Sofi E. Eriksson, Ying Yu Liang, Emarndeena H. Cheteh, Si Min Zhang, Kenji M. Fujihara, Julie Bianchi, Vladimir J. N. Bykov, Lars Abrahmsen, Nicholas J. Clemons, Pär Nordlund, Sean G. Rudd, Klas G. Wiman
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7a30218a8b2c440c80e8a3b947cee01f
Autor:
Jong Shin, Hannan Mir, Maaz A. Khurram, Kenji M. Fujihara, Brian D. Dynlacht, Timothy J. Cardozo, Richard Possemato
Publikováno v:
Nature Metabolism. 5:277-293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::001f8741fe24fea509bfd9cfab3e7674
https://doi.org/10.1038/s42255-023-00735-9
https://doi.org/10.1038/s42255-023-00735-9
Autor:
Yilin Kang, Alexander J Anderson, Thomas Daniel Jackson, Catherine S Palmer, David P De Souza, Kenji M Fujihara, Tegan Stait, Ann E Frazier, Nicholas J Clemons, Deidreia Tull, David R Thorburn, Malcolm J McConville, Michael T Ryan, David A Stroud, Diana Stojanovski
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/2d1831cdc40a485f949b44ba981fa33e
Autor:
Carlos S. Cabalag, Owen W. J. Prall, John Ciciulla, Laurence A. Galea, Niko Thio, Madawa Jayawardana, Trishe Y. M. Leong, Julia V. Milne, Kenji M. Fujihara, Lynn Chong, Michael W. Hii, Gisela Mir Arnau, Paul J. Neeson, Wayne A. Phillips, Cuong P. Duong, Nicholas J. Clemons
Publikováno v:
Annals of Surgical Oncology. 30:1614-1625
Background In esophageal cancer (EC), there is a paucity of knowledge regarding the interplay between the tumor immune microenvironment and response to neoadjuvant treatment and, therefore, which factors may influence outcomes. Thus, our goal was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::935613760b2860f468023539fcb53bff
https://doi.org/10.1245/s10434-022-12562-5
https://doi.org/10.1245/s10434-022-12562-5
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 986 (2021)
A critical hallmark of cancer cells is their ability to evade programmed apoptotic cell death. Consequently, resistance to anti-cancer therapeutics is a hurdle often observed in the clinic. Ferroptosis, a non-apoptotic form of cell death distinguishe
Externí odkaz:
https://doaj.org/article/55e6bfc7b61e463cb57689f021384047