Zobrazeno 1 - 10
of 1 893
pro vyhledávání: '"M, Frenkel"'
Autor:
Ingrid A. Beck, Ceejay L. Boyce, Marley D. Bishop, Yen L. Vu, Amanda Fung, Sheila Styrchak, Nuttada Panpradist, Barry R. Lutz, Lisa M. Frenkel
Publikováno v:
Viruses, Vol 16, Iss 7, p 1162 (2024)
The WHO currently recommends dolutegravir (DTG)-based ART for persons living with HIV infection in resource-limited-settings (RLS). To expand access to testing for HIV drug resistance (DR) to DTG in RLS, we developed probes for use in the oligonucleo
Externí odkaz:
https://doaj.org/article/5eae2802cfbd4e7381fdb8a745ba669d
Autor:
Ewelina Kosmider, Jackson Wallner, Ana Gervassi, Rachel A. Bender Ignacio, Delia Pinto-Santini, German Gornalusse, Urvashi Pandey, Florian Hladik, Paul T. Edlefsen, Javier R. Lama, Ann C. Duerr, Lisa M. Frenkel
Publikováno v:
PLoS ONE, Vol 19, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/26834e94fd194993af374bc9e1aee01c
Autor:
Marcela Viviana Karpuj, D. R. Shaytov, Yonat Shemer-Avni, Michael Gideon, Zakharia M. Frenkel, Sarit Sivan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5764 (2024)
In the face of the SARS-CoV-2 pandemic, characterized by the virus’s rapid mutation rates, developing timely and targeted therapeutic and diagnostic interventions presents a significant challenge. This study utilizes bioinformatic analyses to pinpo
Externí odkaz:
https://doaj.org/article/075eb5ce2f4d45b58e1bb69f114aac4e
Autor:
Daisy Ko, Sherry McLaughlin, Wenjie Deng, James I. Mullins, Joan Dragavon, Socorro Harb, Robert W. Coombs, Lisa M. Frenkel
Publikováno v:
Viruses, Vol 16, Iss 4, p 510 (2024)
HIV-1 typically infects cells via the CD4 receptor and CCR5 or CXCR4 co-receptors. Maraviroc is a CCR5-specific viral entry inhibitor; knowledge of viral co-receptor specificity is important prior to usage. We developed and validated an economical V3
Externí odkaz:
https://doaj.org/article/f23c85245d7049c8b39453509c2488f3
Autor:
Seth C Inzaule, Mark J Siedner, Susan J Little, Santiago Avila-Rios, Alisen Ayitewala, Ronald J Bosch, Vincent Calvez, Francesca Ceccherini-Silberstein, Charlotte Charpentier, Diane Descamps, Susan H Eshleman, Joseph Fokam, Lisa M Frenkel, Ravindra K Gupta, John P A Ioannidis, Pontiano Kaleebu, Rami Kantor, Seble G Kassaye, Sergei L Kosakovsky Pond, Vinie Kouamou, Roger D Kouyos, Daniel R Kuritzkes, Richard Lessells, Anne-Genevieve Marcelin, Lawrence Mbuagbaw, Brian Minalga, Nicaise Ndembi, Richard A Neher, Roger Paredes, Deenan Pillay, Elliot G Raizes, Soo-Yon Rhee, Douglas D Richman, Kiat Ruxrungtham, Pardis C Sabeti, Jonathan M Schapiro, Sunee Sirivichayakul, Kim Steegen, Wataru Sugiura, Gert U van Zyl, Anne-Mieke Vandamme, Annemarie M J Wensing, Joel O Wertheim, Huldrych F Gunthard, Michael R Jordan, Robert W Shafer
Publikováno v:
PLoS Medicine, Vol 20, Iss 9, p e1004293 (2023)
• Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that
Externí odkaz:
https://doaj.org/article/c16a34440b374c53938659e86b679144
Autor:
Lisa Abuogi, Patrick Oyaro, Garoma Wakjira, Katherine K. Thomas, Andrea J. Scallon, Irene Mukui, Bhavna H. Chohan, Evelyn Brown, Enericah Karauki, Nashon Yongo, Bilaal Ahmed, Shukri A. Hassan, James Wagude, Eunice Kinywa, Linda Otieno, Leonard Kingwara, Boaz Oyaro, Lisa M. Frenkel, Grace John-Stewart, Rena C. Patel
Publikováno v:
Viruses, Vol 15, Iss 10, p 2083 (2023)
Increasing HIV drug resistance (DR) among children with HIV (CHIV) on antiretroviral treatment (ART) is concerning. CHIV ages 1–14 years enrolled from March 2019 to December 2020 from five facilities in Kisumu County, Kenya, were included. Children
Externí odkaz:
https://doaj.org/article/20cd808718e747df9d27609220e13b9f
Autor:
Ingrid A. Beck, Sheila Styrchak, Leslie Miller, Fred Mast, Vladimir Vigdorovich, Winnie Yeung, Daisy Ko, Alyssa Oldroyd, Samantha Hardy, Song Li, John Houck, Yonghou Jiang, Nicholas Dambrauskas, Catherine Darcey, Andrew Raappana, William Selman, D. Noah Sather, John D. Aitchison, Whitney E. Harrington, Lisa M. Frenkel
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Biomedical personnel can become contaminated with nonhazardous reagents used in the laboratory. We describe molecular studies performed on nasal secretions collected longitudinally from asymptomatic laboratory coworkers to determine if they
Externí odkaz:
https://doaj.org/article/cf5e3aaaf69246148f1a08716589f2ef
Autor:
Justin D Vrana, Nuttada Panpradist, Nikki Higa, Daisy Ko, Parker Ruth, Ruth Kanthula, James J Lai, Yaoyu Yang, Samar R Sakr, Bhavna Chohan, Michael H Chung, Lisa M Frenkel, Barry R Lutz, Eric Klavins, Ingrid A Beck
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 2, p e0000185 (2022)
Usability is an overlooked aspect of implementing lab-based assays, particularly novel assays in low-resource-settings. Esoteric instructions can lead to irreproducible test results and patient harm. To address these issues, we developed a software a
Externí odkaz:
https://doaj.org/article/dcdfb395c1bb4ae6a750cadd407f1b57
Autor:
Whitney E. Harrington, Winnie Yeung, Ingrid A. Beck, Fred D. Mast, John Houck, Sheila Styrchak, Leslie R. Miller, Song Li, Micaela Haglund, Yonghou Jiang, Blair Armistead, Jackson Wallner, Tina Nguyen, Daisy Ko, Samantha Hardy, Alyssa Oldroyd, Ana Gervassi, John D. Aitchison, Lisa M. Frenkel
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Background Asymptomatic and pre-symptomatic SARS-CoV-2 infections may contribute to ongoing community transmission, however, the benefit of routine screening of asymptomatic individuals in low-risk populations is unclear. Methods To identify SARS-CoV
Externí odkaz:
https://doaj.org/article/eef1ebf3b2da434aa54c155bced8b70e
Autor:
Ceejay L. Boyce, Ingrid A. Beck, Sheila M. Styrchak, Samantha R. Hardy, Jackson J. Wallner, Ross S. Milne, R. Leavitt Morrison, David E. Shapiro, Esaú C. João, Mark H. Mirochnick, Lisa M. Frenkel
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
Objective To assess in ART-naïve pregnant women randomized to efavirenz- versus raltegravir-based ART (IMPAACT P1081) whether pretreatment drug resistance (PDR) with minority frequency variants (Design A case-control study design compared PDR minori
Externí odkaz:
https://doaj.org/article/6414adc493424b66ae36a468a952de97