Zobrazeno 1 - 10
of 210
pro vyhledávání: '"M, Flinn"'
Autor:
Catherine King, Katie Ridge, James Smyth, Aisling M. Flinn, Timothy Ronan Leahy, Niall Conlon
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The effective transition from pediatric to adult care for individuals with chronic medical conditions should address the medical, psychosocial and educational needs of the cohort. The views and experiences of service users and their families are an i
Externí odkaz:
https://doaj.org/article/d48650f28a6743b195857352f85da06f
Autor:
Aisling M. Flinn, Andrew R. Gennery
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)
Abstract Primary Immune Regulatory Disorders (PIRD) describe a group of conditions characterized by loss of normal inflammatory control and immune tolerance mechanisms, with autoimmunity as a predominant clinical feature. PIRD can arise due to defect
Externí odkaz:
https://doaj.org/article/a4d1e70482174d01b7f530dbb8910ab7
Autor:
Ines Bojanic, Nina Worel, Carolina P. Pacini, Georg Stary, Agnieszka Piekarska, Aisling M. Flinn, Kimberly J. Schell, Andrew R. Gennery, Robert Knobler, João F. Lacerda, Hildegard T. Greinix, Drazen Pulanic, Rachel E. Crossland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Haematopoietic stem cell transplantation (HSCT) is the treatment of choice for malignant haematological diseases. Despite continuous improvements in pre- and post-transplantation procedures, the applicability of allo-HSCT is limited by life-threateni
Externí odkaz:
https://doaj.org/article/c94a325df4744cc9a0f8e259d3242b5d
Autor:
Carlos M. Hernandez, Rachel E. Barkey, Kristen M. Craven, Karin A. Pedemonte, Bernadette Alisantosa, Jonathan O. Sanchez, Jane M. Flinn
Publikováno v:
Brain Sciences, Vol 13, Iss 6, p 841 (2023)
Alzheimer’s disease (AD) is characterized by the buildup of plaques and tangles in the brain. Tangles are formed when the stabilizing protein, tau, becomes hyperphosphorylated and clumps together. There are limited treatments for AD; therefore, the
Externí odkaz:
https://doaj.org/article/cd406f4ba4fd48b5afbc75b391c3a736
Autor:
Aisling M. Flinn, Sheba Macheka, Mary Slatter, Anna‐Maria Ewins, Brenda Gibson, Sarah Lawson, Anna Tailby, Giovanna Lucchini, Helen New, Beki James, Arun Alfred, Julia Scarisbrick, Andrew R Gennery
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 293-296 (2020)
Abstract Extracorporeal photopheresis (ECP) is a second‐line therapy in acute and chronic GVHD and solid organ transplant rejection. We report ECP use in 98 pediatric patients in seven UK centers from 2010 to 2017, the majority treated for aGVHD (7
Externí odkaz:
https://doaj.org/article/81a491e2ead84b02aac34f659c1c1c33
Autor:
Thalia T. Dimopoulos, Stephen L. P. Lippi, Jorge Fernandez Davila, Rachel E. Barkey, Erin N. Doherty, Jane M. Flinn
Publikováno v:
Brain Sciences, Vol 12, Iss 10, p 1364 (2022)
Alzheimer’s Disease (AD) is characterized by cognitive impairment and the presence of amyloid-β (Aβ) plaques and tau tangles. This study was conducted to assess the effects of white button mushroom (WBM) supplementation on spatial memory and plaq
Externí odkaz:
https://doaj.org/article/361fbefc9bef46868845152ed52b17a9
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer’s disease (AD) is a neurocognitive disorder that impacts both the brain and behavior. Metal ions, including zinc (Zn), have been seen to play an important role in AD-related pathology. In this study, we show alterations in wheel-running b
Externí odkaz:
https://doaj.org/article/4d5fef8ab68b4a52ab6dd1febe21c570
Autor:
Aisling M. Flinn, Andrew R. Gennery
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-7 (2018)
Abstract Adenosine deaminase (ADA) deficiency leads to an accumulation of toxic purine degradation by-products, most potently affecting lymphocytes, leading to adenosine deaminase-deficient severe combined immunodeficiency. Whilst most notable affect
Externí odkaz:
https://doaj.org/article/d4cce96719dc45dea8391acb4bee4f90
Autor:
Aisling M Flinn, Andrew R Gennery
Publikováno v:
Faculty Reviews. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac3e6b7cee3caec38ddf8e0d0ea97219
https://doi.org/10.12703/r/12-4
https://doi.org/10.12703/r/12-4
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The brains of those with Alzheimer's disease have amyloid and tau pathology; thus, mice modeling AD should have both markers. In this study, we characterize offspring from the cross of the J20 (hAPP) and rTg4510 (htau) strains (referred to as dual Tg
Externí odkaz:
https://doaj.org/article/bbe3ca26c58c4deab10c66455d4a0c62