Zobrazeno 1 - 10
of 44
pro vyhledávání: '"M, Flactif"'
Autor:
Nathalie Trillot, M. Flactif, Thierry Facon, Francis Bauters, Marc Zandecki, Franck Bernardi, Jean Luc Laï
Publikováno v:
Cancer Genetics and Cytogenetics. 76:10-14
Two patients with multiple myeloma and an unbalanced translocation, t(1;16)(p11;p11), are reported. The fluorescence in situ hybridization (FISH) technique was used in one patient to confirm the translocation. To our knowledge, t(1;16)(p36;q13) and t
Autor:
M, Zandecki, F, Bernardi, F, Genevieve, J L, Laï, C, Preudhomme, M, Flactif, A, Cosson, F, Bauters, T, Facon
Publikováno v:
Leukemia. 11(7)
The mononuclear cells in the peripheral blood are implicated in the myeloma process especially with the presence of peripheral blood plasma cells (PBPC) and clonal B lymphocytes found using phenotypic or gene rearrangement techniques. The purpose of
Publikováno v:
Leukemia. 9(12)
Conventional cytogenetic (CC) studies performed in multiple myeloma (MM) are difficult because of the low proliferation rate of plasma cells (PC). The purpose of this study was to compare results obtained by CC and by FISH for the detection of numeri
Autor:
Valerie Obein, Jean Luc Laï, Franck Bernardi, Michel Francois, Marc Zandecki, Valérie Soenen, M. Flactif, Thierry Facon
Publikováno v:
British journal of haematology. 90(3)
Summary. We used two indirect approaches [image analysis (Feulgen staining) and fluorescence in situ hybridization (FISH)] to study bone marrow plasma cells (BMPC) in 28 patients fulfilling criteria for MGUS. 61% of patients were found to be aneuploi
Autor:
M. Flactif, Pascale Lepelley, Pierre Fenaux, A. Cosson, Jean Luc Laï, Valérie Soenen, Claude Preudhomme
Publikováno v:
British journal of haematology. 90(3)
Summary. We present a study in which we used a recently described method combining fluorescence in situ hybridization (FISH) and immunophenotyping, i.e. FICTION, to assess the involvement of different cell lineages in myelodysplastic syndrome (MDS) w
Autor:
Jean Yves Mary, Marc Zandecki, Jean Pierre Jouet, Franck Bernardi, Francis Bauters, Jean Luc Laï, Pierre Morel, Thierry Facon, M. Flactif, Véronique Izydorczyk
Publikováno v:
Blood. 85(9)
Between December 1990 and January 1994, bone marrow (BM) samples from 151 patients with multiple myeloma (MM), including 117 patients evaluated at diagnosis, were collected for cytogenetic analysis. A total of 129 patients had assessable metaphases (
Autor:
J L, Lai, C, Preudhomme, M, Zandecki, M, Flactif, M, Vanrumbeke, P, Lepelley, E, Wattel, P, Fenaux
Publikováno v:
Leukemia. 9(3)
We looked for correlations between cytogenetic rearrangements leading to 17p deletion and presence of dysgranulopoïesis and p53 mutations in MDS and AML. Forty-nine (4.3%) of the MDS and AML studied cytogenetically at our institution over a period o
Publikováno v:
Cancer genetics and cytogenetics. 78(1)
We report a published case of chronic lymphocytic leukemia (CLL) in which conventional cytogenetic analysis supported the presence of an unbalanced t(12;17)(p11;p11). However, fluorescence in situ hybridization (FISH) analysis, with specific DNA libr
Fluorescence in situ hybridization improves the detection of monosomy 7 in myelodysplastic syndromes
Publikováno v:
Leukemia. 8(6)
We performed conventional cytogenetic (CC) and interphase fluorescence in situ hybridization (FISH) analysis with an alpha satellite chromosome 7 specific DNA centromeric probe (p alpha 7t1) on bone marrow material prepared for CC in 11 controls and
Autor:
J B, Savary, F, Vasseur, M, Flactif, L, Willatt, J, Lefebvre, M A, Ferguson-Smith, M M, Deminatti
Publikováno v:
Annales de genetique. 35(3)
A derivative Y chromosome was found in a 55-year-old man with Lambert-Eaton paraneoplasic pseudomyastheniform disease. Small testicles, azoospermia were noticed and hormonal level values were as in the Klinefelter syndrome. A 45,X/46,XYp+ mosaïcism