The ASTRI Mini-Array of Cherenkov Telescopes at the Observatorio del Teide

Autor: S., Scuderi, A., Giuliani, G., Pareschi, G., Tosti, O., Catalano, E., Amato, A., Antonelli L., J., Becerra Gonzáles, G., Bellassai, Bigongiari, B., Biondo, M., Böttcher, G., Bonanno, G., Bonnoli, P., Bruno, A., Bulgarelli, R., Canestrari, M., Capalbi, P., Caraveo, M., Cardillo, V., Conforti, G., Contino, M., Corpora, A., Costa, G., Cusumano, A., D'Aí, E., de Gouveia Dal Pino, R., Della Ceca, D., Escribano Rodriguez E. Falceta Gonçalves, C., Fermino, M., Fiori, V., Fioretti, M., Fiorini, S., Gallozzi, C., Gargano, S., Garozzo, S., Germani, A., Ghedina, F., Gianotti, S., Giarrusso, R., Gimenes, V., Giordano, A., Grillo, C., Grivel Gelly, D., Impiombato, F., Incardona, S., Incorvaia, S., Iovenitti, A., La Barbera, N., La Palombara, V., La Parola, A., Lamastra, L., Lessio, G., Leto, F., Lo Gerfo, M., Lodi, S., Lombardi, F., Longo, F., Lucarelli, C., Maccarone M., D., Marano, E., Martinetti, S., Mereghetti, A., Micciché, R., Millul, T., Mineo, D., Mollica, G., Morlino, A., Morselli, G., Naletto, G., Nicotra, A., Pagliaro, N., Parmiggiani, G., Piano, F., Pintore, E., Poretti, B., Olmi, G., Rodeghiero, G., Rodriguez Fernandez, P., Romano, G., Romeo, F., Russo, P., Sangiorgi, G., Saturni F., H., Schwarz J., Sciacca, G., Sironi, G., Sottile, A., Stamerra, G., Tagliaferri, V., Testa, G., Umana, M., Uslenghi, S., Vercellone, L., Zampieri, R, Zanmar Sanchez

Publikováno v: Journal of High Energy Astrophysics, Volume 35, p. 52-68 (2022)

The ASTRI Mini-Array (MA) is an INAF project to build and operate a facility to study astronomical sources emitting at very high-energy in the TeV spectral band. The ASTRI MA consists of a group of nine innovative Imaging Atmospheric Cherenkov telesc

Externí odkaz: http://arxiv.org/abs/2208.04571

SNORD90 induces glutamatergic signaling following treatment with monoaminergic antidepressants

Autor: Rixing Lin, Aron Kos, Juan Pablo Lopez, Julien Dine, Laura M Fiori, Jennie Yang, Yair Ben-Efraim, Zahia Aouabed, Pascal Ibrahim, Haruka Mitsuhashi, Tak Pan Wong, El Cherif Ibrahim, Catherine Belzung, Pierre Blier, Faranak Farzan, Benicio N Frey, Raymond W Lam, Roumen Milev, Daniel J Muller, Sagar V Parikh, Claudio Soares, Rudolf Uher, Corina Nagy, Naguib Mechawar, Jane A Foster, Sidney H Kennedy, Alon Chen, Gustavo Turecki

Publikováno v: eLife, Vol 12 (2023)

Pharmacotherapies for the treatment of major depressive disorder were serendipitously discovered almost seven decades ago. From this discovery, scientists pinpointed the monoaminergic system as the primary target associated with symptom alleviation.

Externí odkaz: https://doaj.org/article/40f97f541aac443b8777dc3821cea8f3

Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder

Autor: Rixing Lin, Juan Pablo Lopez, Cristiana Cruceanu, Caroline Pierotti, Laura M. Fiori, Alessio Squassina, Caterina Chillotti, Christoph Dieterich, Nikolaos Mellios, Gustavo Turecki

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)

Abstract Gene expression dysregulation in the brain has been associated with bipolar disorder, but little is known about the role of non-coding RNAs. Circular RNAs are a novel class of long noncoding RNAs that have recently been shown to be important

Externí odkaz: https://doaj.org/article/e1375c7f13de497ab883d11db3beb395

Association between the expression of lncRNA BASP-AS1 and volume of right hippocampal tail moderated by episode duration in major depressive disorder: a CAN-BIND 1 report

Autor: Antoine Yrondi, Laura M. Fiori, Nikita Nogovitsyn, Stefanie Hassel, Jean François Théroux, Zahia Aouabed, Benicio N. Frey, Raymond W. Lam, Roumen Milev, Daniel J. Müller, Jane A. Foster, Claudio Soares, Susan Rotzinger, Stephen C. Strother, Glenda M. MacQueen, Stephen R. Arnott, Andrew D. Davis, Mojdeh Zamyadi, Jacqueline Harris, Sidney H. Kennedy, Gustavo Turecki

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)

Abstract The pathophysiology of major depressive disorder (MDD) encompasses an array of changes at molecular and neurobiological levels. As chronic stress promotes neurotoxicity there are alterations in the expression of genes and gene-regulatory mol

Externí odkaz: https://doaj.org/article/065d0f0350c1425896a0f36f31046e58

GPR56/ADGRG1 is associated with response to antidepressant treatment

Autor: Raoul Belzeaux, Victor Gorgievski, Laura M. Fiori, Juan Pablo Lopez, Julien Grenier, Rixing Lin, Corina Nagy, El Chérif Ibrahim, Eduardo Gascon, Philippe Courtet, Stéphane Richard-Devantoy, Marcelo Berlim, Eduardo Chachamovich, Jean-François Théroux, Sylvie Dumas, Bruno Giros, Susan Rotzinger, Claudio N. Soares, Jane A. Foster, Naguib Mechawar, Gregory G. Tall, Eleni T. Tzavara, Sidney H. Kennedy, Gustavo Turecki

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

It is not fully understood why some patients respond or do not respond to antidepressant treatment. Here the authors show that in the blood of individuals with depression, GPR56 expression increases in responders to antidepressant treatment, but not

Externí odkaz: https://doaj.org/article/3469c4a94a4c4f539ae3e87d5f59f012