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Akademický článek

Regulatory histories of recently withdrawn ovarian cancer treatment indications of 3 PARP inhibitors in the US and Europe: lessons for the accelerated approval pathway

Autor: Mahnum Shahzad, Huseyin Naci, Katharine M. Esselen, Joseph A. Dottino, Anita K. Wagner

Publikováno v: Journal of Pharmaceutical Policy and Practice, Vol 17, Iss 1 (2024)

Background Withdrawals of drug indications may reveal potential inadequacies in the regulatory approval processes of new drugs. Understanding potential weaknesses of the regulatory approval process is paramount given the increasing use of expedited p

Externí odkaz: https://doaj.org/article/67e6023f0d1c4d449c59706d21db22e0

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Akademický článek

Targeting Cbx3/HP1γ Induces LEF-1 and IL-21R to Promote Tumor-Infiltrating CD8 T-Cell Persistence

Autor: Phuong T. Le, Ngoc Ha, Ngan K. Tran, Andrew G. Newman, Katharine M. Esselen, John L. Dalrymple, Eva M. Schmelz, Avinash Bhandoola, Hai-Hui Xue, Prim B. Singh, To-Ha Thai

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Immune checkpoint blockade (ICB) relieves CD8+ T-cell exhaustion in most mutated tumors, and TCF-1 is implicated in converting progenitor exhausted cells to functional effector cells. However, identifying mechanisms that can prevent functional senesc

Externí odkaz: https://doaj.org/article/5046e0f6247a45a98a6ec88b1cfc1444

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Financial toxicity: A practical review for gynecologic oncology teams to understand and address patient-level financial burdens

Autor: Margaret I. Liang, Ross Harrison, Emeline M. Aviki, Katharine M. Esselen, Roni Nitecki, Larissa Meyer

Publikováno v: Gynecologic Oncology. 170:317-327

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::407c8dd311102b2625dbd97dc8bfbb44
https://doi.org/10.1016/j.ygyno.2023.01.035

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Financial toxicity in pregnancy and postpartum

Autor: Annika Gompers, Elysia Larson, Katharine M. Esselen, Huma Farid, Laura E. Dodge

Publikováno v: Birth.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::502b902d362242061061b8123a7427d5
https://doi.org/10.1111/birt.12710

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Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA

Autor: J. Kleinehr, K. Daniel, F. Günl, J. Janowski, L. Brunotte, M. Liebmann, M. Behrens, A. Gerdemann, L. Klotz, M. Esselen, H.-U. Humpf, S. Ludwig, E. R. Hrincius

Influenza A virus (IAV), like any other virus, provokes considerable modifications of its host cell’s metabolism. This includes a substantial increase in the uptake as well as the metabolization of glucose. Although it is known for quite some time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdf66e3be7aba1d86aa9051efeabf756
https://doi.org/10.1101/2022.11.09.515749

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Zytotoxische Epigallocatechingallat‐Autoxidationsprodukte in Tee: Isolierung, Charakterisierung und Quantifizierung

Autor: J. Alfke, U. Kampermann, M. Esselen

Publikováno v: Lebensmittelchemie. 76

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::223fc9f97a9bd51ec51b600cbc799b61
https://doi.org/10.1002/lemi.202259184

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Persistence and clearance of high‐risk human papillomavirus and cervical dysplasia at 1 year in women living with human immunodeficiency virus: a prospective cohort study

Autor: Adrienne L. Erlinger, Michele R. Hacker, Boikhutso Simon, Doreen Ramogola-Masire, Sikhulile Moyo, Rebecca Luckett, Cortney Eakin, Lynnette Tumwine Kyokunda, Katharine M. Esselen, Alexander Seiphetlheng, Helena Painter, Chelsea Morroni, Sarah Feldman

Publikováno v: BJOG

OBJECTIVE Evaluate 1-year outcomes of cervical cancer screening and treatment using primary high-risk human papillomavirus (HPV) testing in women living with human immunodeficiency virus (HIV). DESIGN Prospective cohort study. SETTING HIV treatment c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1958c42e30317190ac968a814d4a1d
https://doi.org/10.1111/1471-0528.16758

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Crowdsourcing to measure financial toxicity in gynecologic oncology

Autor: Katharine M. Esselen, Annika Gompers, Hannah Stack-Dunnbier, Michele R. Hacker

Publikováno v: Gynecol Oncol

OBJECTIVE: To utilize a novel crowdsourcing method to measure financial toxicity and its effects amongst a national cohort of gynecologic cancer patients. METHODS: Crowdsourcing methods were used to administer an online survey to women in the United

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556b97fffb0426085ab8545932d9a14a
https://doi.org/10.1016/j.ygyno.2021.01.040

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Evaluating meaningful levels of financial toxicity in gynecologic cancers

Autor: Lindsay Rucker, Katharine M. Esselen, Sarah S. Summerlin, Warner K. Huh, Meghan Shea, Sara Bouberhan, Maria Pisu, Margaret I. Liang, Michele R. Hacker, Annika Gompers

Publikováno v: International Journal of Gynecologic Cancer. 31:801-806

ObjectiveThe Comprehensive Score for Financial Toxicity (COST) is a validated instrument measuring the economic burden experienced by patients with cancer. We evaluated the frequency of financial toxicity at different COST levels and stratified risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee323614c83d7c3e57b8563e8d6d9760
https://doi.org/10.1136/ijgc-2021-002475

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