Ivermectin reduces in vivo coronavirus infection in a mouse experimental model

Autor: Romina Pagotto, Jorge Luis Pórfido, Hellen Daghero, Marcelo Hill, B. Varela, Ana Paula Arévalo, M. Duhalde Vega, Martina Crispo, Mercedes Segovia, Mariela Bollati-Fogolín, Kanji Yamasaki, José Manuel Verdes

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

SARS-CoV2 is a single strand RNA virus member of the type 2 coronavirus family, responsible for causing COVID-19 disease in humans. The objective of this study was to test the ivermectin drug in a murine model of coronavirus infection using a type 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e3b95a68c02f7341d0608715b1f924
https://pubmed.ncbi.nlm.nih.gov/33785846

Properties of Cryptic Epitopes and Their Corresponding Antibodies as Indicated by the Study of Human and Ovine Growth Hormones

Autor: Maria Eugenia Loureiro, Lilia A. Retegui, M. Duhalde, Veronica Julieta Marino, Patricia Andrea Mathieu, Clara Peña, Leonor P. Roguin

Publikováno v: Immunological Investigations. 36:159-174

Antibodies (Ab) directed to hidden antigenic determinants (cryptotopes) are undesirable because they are not neutralizing. Additionally, we have previously demonstrated a close association between the extent of Ab to cryptic determinants and the expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca087fcaed9b83dc81ed1925495d0032
https://doi.org/10.1080/08820130600941179

A high performance modular embedded ROM architecture

Autor: A. Greiner, F. Petrot, M. Duhalde

Publikováno v: ISCAS

We describe a CMOS Read Only Memory architecture designed for high performances and low power consumption using domino logic. Short read delays are achieved using hierarchical evaluation of the read busses, at the price of some more material. Partial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e3c032c9610c335b5561f6794006df6
https://doi.org/10.1109/iscas.1995.519949

[Imipenem/cilastatin versus ceftazidime-amikacin in the treatment of febrile neutropenic patients]

Autor: C, Pérez, M, Sirham, J, Labarca, G, Grebe, P, Lira, J, Oliva, M, Duhalde, M, Ocqueteau, G, Acuña

Publikováno v: Revista medica de Chile. 123(3)

To compare the efficacy of imipenem/cilastatine and ceftazidime-amikacin in the treatment of febrile neutropenic patients.Open, prospective and randomized clinical study.Fifty two patients (26 female) aged 16 to 80 years old with 60 episodes of neutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76720be50b426d596e7702b2f615737e
https://pubmed.ncbi.nlm.nih.gov/8525170

[Severe hyponatremia in acute porphyria. Central pontine myelinolysis as a complication of its treatment]

Autor: M, Duhalde, R, Téllez, P, Michaud, E, Sepúlveda

Publikováno v: Revista medica de Chile. 118(10)

Two patients developed severe hyponatremia attributed to inappropriate antidiuretic hormone secretion during a crisis of acute porphyria, and were treated with intravenous hypertonic sodium solution. One of them developed clinical and radiological fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9cb8a67697ba9c92a5a2d3cd7ad0ed9
https://pubmed.ncbi.nlm.nih.gov/2152632