Zobrazeno 1 - 10 of 118 pro vyhledávání: '"M, Dark"'
1
Akademický článek
Developing a roadmap to improve trial delivery for under-served groups: results from a UK multi-stakeholder process
Autor: Miles D. Witham, Eleanor Anderson, Camille Carroll, Paul M. Dark, Kim Down, Alistair S. Hall, Joanna Knee, Rebecca H. Maier, Gail A. Mountain, Gary Nestor, Laurie Oliva, Sarah R. Prowse, Amanda Tortice, James Wason, Lynn Rochester, On behalf of the INCLUDE writing group
Publikováno v: Trials, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Participants in clinical research studies often do not reflect the populations for which healthcare interventions are needed or will be used. Enhancing representation of under-served groups in clinical research is important to ens
Externí odkaz: https://doaj.org/article/ce9cbafbc72c4160a9289812174aeb51
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2
Analysis of exhaled breath to identify critically ill patients with ventilator‐associated pneumonia
Autor: T. W. Felton, W. Ahmed, I. R. White, P. van Oort, N. J. W. Rattray, C. Docherty, J. Bannard‐Smith, B. Morton, I. Welters, R. McMullan, S. A. Roberts, R. Goodacre, P. M. Dark, S. J. Fowler
Publikováno v: Felton, T W, Ahmed, W, White, I R, van Oort, P, Rattray, N J W, Docherty, C, Bannard-Smith, J, Morton, B, Welters, I, McMullan, R, Roberts, S A, Goodacre, R, Dark, P M & Fowler, S J 2023, ' Analysis of exhaled breath to identify critically ill patients with ventilator-associated pneumonia ', Anaesthesia, vol. 78, no. 6, pp. 712-721 . https://doi.org/10.1111/anae.15999
Felton, T W, Ahmed, W, White, I R, van Oort, P, Rattray, N J W, Docherty, C, Bannard-Smith, J, Morton, B, Welters, I, McMullan, R, Roberts, S A, Goodacre, R, Dark, P M & Fowler, S J 2023, ' Analysis of exhaled breath to identify critically ill patients with ventilator-associated pneumonia ', Anaesthesia . https://doi.org/10.1111/anae.15999
Summary: Ventilator‐associated pneumonia commonly occurs in critically ill patients. Clinical suspicion results in overuse of antibiotics, which in turn promotes antimicrobial resistance. Detection of volatile organic compounds in the exhaled breat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c569cd825f9d92e2f4afea2cf8e253
https://doi.org/10.1111/anae.15999
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3
Akademický článek
Ensuring that COVID-19 research is inclusive: guidance from the NIHR INCLUDE project
Autor: Miles D Witham, Alistair S Hall, Camille B Carroll, Eamonn R Maher, Rebecca H Maier, Eleanor Anderson, Paul M Dark, Kim Down, Joanna Knee, Gail A Mountain, Gary Nestor
Publikováno v: BMJ Open, Vol 10, Iss 11 (2020)
Objective To provide guidance to researchers, funders, regulators and study delivery teams to ensure that research on COVID-19 is inclusive, particularly of groups disproportionately affected by COVID-19 and who may have been historically under-serve
Externí odkaz: https://doaj.org/article/15758e1e582b4f70ad14524cf725e4a0
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4
Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx)
Autor: Pouline Mp, van Oort, Tamara M, Nijsen, Iain R, White, Hugo H, Knobel, Timothy, Felton, Nicholas, Rattray, Oluwasola, Lawal, Murtaza, Bulut, Waqar, Ahmed, Antonio, Artigas, Pedro R, Povoa, Ignacio, Martin-Loeches, Hans, Weda, Royston, Goodacre, Marcus J, Schultz, Paul M, Dark, Stephen J, Fowler, Lieuwe D, Bos, Tetyana, Zakharkina
Publikováno v: BreathDx Consortium, van Oort, P M, Nijsen, T M, White, I R, Knobel, H H, Felton, T, Rattray, N, Lawal, O, Bulut, M, Ahmed, W, Artigas, A, Povoa, P R, Martin-Loeches, I, Weda, H, Goodacre, R, Schultz, M J, Dark, P M, Fowler, S J & Bos, L D 2022, ' Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx) ', Thorax, vol. 77, no. 1, pp. 79-81 . https://doi.org/10.1136/thoraxjnl-2021-217362
Thorax, 77(1):217362, 79-81. BMJ Publishing Group
van Oort, P M, Nijsen, T M, White, I R, Knobel, H H, Felton, T, Rattray, N, Lawal, O, Bulut, M, Ahmed, W, Artigas, A, Povoa, P R, Martin-Loeches, I, Weda, H, Goodacre, R, Schultz, M J, Dark, P M, Fowler, S J & Bos, L D 2022, ' Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx) ', Thorax, vol. 77, no. 1, pp. 79-81 . https://doi.org/10.1136/thoraxjnl-2021-217362
Thorax, 77(1), 79-81. BMJ Publishing Group
Thorax
Patients suspected of ventilator-associated lower respiratory tract infections (VA-LRTIs) commonly receive broad-spectrum antimicrobial therapy unnecessarily. We tested whether exhaled breath analysis can discriminate between patients suspected of VA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78097ec60e1a378d79dffa8da9aea614
https://doi.org/10.1136/thoraxjnl-2021-217362
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5
Akademický článek
Removal of Contaminant DNA by Combined UV-EMA Treatment Allows Low Copy Number Detection of Clinically Relevant Bacteria Using Pan-Bacterial Real-Time PCR.
Autor: Bruce Humphrey, Neil McLeod, Carrie Turner, J Mark Sutton, Paul M Dark, Geoffrey Warhurst
Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0132954 (2015)
More than two decades after its discovery, contaminant microbial DNA in PCR reagents continues to impact the sensitivity and integrity of broad-range PCR diagnostic techniques. This is particularly relevant to their use in the setting of human sepsis
Externí odkaz: https://doaj.org/article/3818a800b21043eda65e7325933558e7
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