Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M, Damez"'
Autor:
Li Shen, Ning-Yi Shao, HaoSheng Sun, Gustavo Turecki, Mohamed Kabbaj, Jacqui Rabkin, Caroline Dias, Diane M. Damez-Werno, Kimberly N. Scobie, Rachael L. Neve, Ezekiell Mouzon, Katherine N. Wright, Eric J. Nestler
Publikováno v:
Neuroscience. 353:1-6
Chromatin regulation, in particular ATP-dependent chromatin remodelers, have previously been shown to be important in the regulation of reward-related behaviors in animal models of mental illnesses. Here we demonstrate that BAZ1A, an accessory subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4484a5657ad6f92fa53a8722e1beeb3f
https://doi.org/10.1016/j.neuroscience.2017.04.007
https://doi.org/10.1016/j.neuroscience.2017.04.007
Autor:
Paul J. Kenny, Amy M. Gancarz, Marine Salery, Jacqui Rabkin, Michael E. Cahill, Yasmin L. Hurd, Rachael L. Neve, Eric J. Nestler, David M. Dietz, Zahra Jlayer, Paola Defilippi, Joseph A. Landry, Craig T. Werner, Erin S. Calipari, Diane M. Damez-Werno, Arthur Godino, Alexander C.W. Smith, Emily G. Peck
Addictive behaviors, including relapse, are thought to depend in part on long-lasting drug-induced adaptations in dendritic spine signaling and morphology in the nucleus accumbens (NAc). While the influence of activity-dependent actin remodeling in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486fe4299b40a3f6fad184510e66c08c
https://europepmc.org/articles/PMC6636087/
https://europepmc.org/articles/PMC6636087/
Autor:
Diane M. Damez-Werno, Caroline Dias, Rachael L. Neve, Ning-Yi Shao, Gustavo Turecki, Jaclyn Rabkin, Mary Kay Lobo, Yasmin L. Hurd, C. David Allis, Ernesto Guccione, Ian Maze, Michael E. Cahill, David M. Dietz, Hannah M. Cates, Amy M. Gancarz, Ezekiell Mouzon, Joseph A. Landry, HaoSheng Sun, Ramesh Chandra, Catherine Jensen Pena, Kimberly N. Scobie, Eric J. Nestler, Paola Defilippi, Deena M. Walker, Erin S. Calipari, Li Shen
Publikováno v:
Proceedings of the National Academy of Sciences. 113:9623-9628
Repeated cocaine exposure regulates transcriptional regulation within the nucleus accumbens (NAc), and epigenetic mechanisms-such as histone acetylation and methylation on Lys residues-have been linked to these lasting actions of cocaine. In contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d34001b710dcd19ea9e7565401a0f85
https://doi.org/10.1073/pnas.1605045113
https://doi.org/10.1073/pnas.1605045113
Autor:
Sam A. Golden, Erica Korb, Jacqui Rabkin, Rosemary C. Bagot, Elizabeth A. Heller, Hannah M. Cates, Carol A. Tamminga, Ning-Yi Shao, Ja Wook Koo, Gustavo Turecki, Li Shen, Diane M. Damez-Werno, Scott J. Russo, Benoit Labonté, Patrick Varga-Weisz, HaoSheng Sun, Caroline Dias, Kelly Gleason, Eric J. Nestler, Pamela J. Kennedy, Kimberly N. Scobie, Ezekiell Mouzon, Ian Maze, David M. Dietz, Francisca H. Ahn, Simon Andrews, C. David Allis, Michael E. Cahill, Rachael L. Neve
Publikováno v:
Nature medicine
Improved treatment for major depressive disorder (MDD) remains elusive because of the limited understanding of its underlying biological mechanisms. It is likely that stress-induced maladaptive transcriptional regulation in limbic neural circuits con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6880d235f88906040c23bda043e040af
https://doi.org/10.1038/nm.3939
https://doi.org/10.1038/nm.3939
Autor:
Virginia Gao, Rachael L. Neve, Jane Magida, David M. Dietz, Eric J. Nestler, Matthew Wilkinson, Diane M. Damez-Werno, Deveroux Ferguson, HaoSheng Sun, Michelle S. Mazei-Robison, Caroline Dias
Publikováno v:
Neuroscience Letters. 598:23-28
Chronic cocaine exposure increases the density of dendritic spines on medium spiny neurons (MSNs), the predominant neuronal cell type of the nucleus accumbens (NAc), a key brain reward region. We recently showed that suppression of Rac1, a small GTPa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908cf494f9914d8dc78abe0daf745df4
https://doi.org/10.1016/j.neulet.2015.05.003
https://doi.org/10.1016/j.neulet.2015.05.003
Autor:
Rosemary C. Bagot, Erin S. Calipari, Michelle S. Mazei-Robison, Ezekiell Mouzon, Li Shen, Efrain Ribeiro, Carol A. Tamminga, Catherine Jensen Pena, HaoSheng Sun, Benoit Labonté, Rachael L. Neve, Xiaochuan Liu, Subroto Ghose, Jian Feng, Caroline Dias, Kimberly N. Scobie, Ning Y.i. Shao, Eric J. Nestler, Pamela J. Kennedy, Vincent Vialou, Ja W.ook Koo, Deveroux Ferguson, Diane M. Damez-Werno
Publikováno v:
Nature. 516:51-55
β-catenin is a multi-functional protein that has an important role in the mature central nervous system; its dysfunction has been implicated in several neuropsychiatric disorders, including depression. Here we show that in mice β-catenin mediates p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c705239b6a7e1016e3b6b233ca7fb4f0
https://doi.org/10.1038/nature13976
https://doi.org/10.1038/nature13976
Autor:
Jennifer A. Martin, Rachael L. Neve, David M. Dietz, Aaron Caccamise, Zi-Jun Wang, Monica S. Humby, Diane M. Damez-Werno, Kevin M Braunscheidel, Amy M. Gancarz, Gabrielle L. Schroeder, Lauren E. Mueller, Karen C. Dietz
Publikováno v:
Nature neuroscience
Cocaine addiction is a life-long relapsing disorder that results from long-term adaptations within the brain. We find that Activin-receptor signaling, including the transcription factor Smad3, is upregulated in the rat nucleus accumbens shell followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bcf1bd9d0769dc99fa84832729bd98
https://doi.org/10.1038/nn.4036
https://doi.org/10.1038/nn.4036
Autor:
Paul J. Kenny, Diane M. Damez-Werno
Publikováno v:
Neuron. 86:853-855
Optogenetics is now a widely accepted tool for spatiotemporal manipulation of neuronal activity. However, a majority of optogenetic approaches use binary on/off control schemes. Here we extend the optogenetic toolset by developing a neuromodulatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbbb7924d9294c93085fec08df2083f
https://doi.org/10.1016/j.neuron.2015.05.014
https://doi.org/10.1016/j.neuron.2015.05.014
Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation
Autor:
Stephen J. Haggarty, Ian Maze, Dipesh Chaudhury, Ming-Hu Han, Eric N. Olson, Jian Feng, Diane M. Damez-Werno, Ana Badimon, Ezekiell Mouzon, Pamela J. Kennedy, Eric J. Nestler, Alfred J. Robison, Rhonda Bassel-Duby
Publikováno v:
Nature neuroscience
Induction of histone acetylation in the nucleus accumbens (NAc), a key brain reward region, promotes cocaine-induced alterations in gene expression. Histone deacetylases (HDACs) tightly regulate the acetylation of histone tails, but little is known a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e227ad722aa90dfba3a9f4b2fc65489
https://doi.org/10.1038/nn.3354
https://doi.org/10.1038/nn.3354
Autor:
Jennifer A. Martin, Craig T. Werner, Li Shen, Rachael L. Neve, Caroline Dias, Ning-Yi Shao, Eric J. Nestler, Amy M. Gancarz, Zi-Jun Wang, David M. Dietz, Jacqui Rabkin, Diane M. Damez-Werno, HaoSheng Sun, Ezekiell Mouzon, Kimberly N. Scobie, Ja Wook Koo
Publikováno v:
Society for Neuroscience
ATP-dependent chromatin remodeling proteins are being implicated increasingly in the regulation of complex behaviors, including models of several psychiatric disorders. Here, we demonstrate thatBaz1b, an accessory subunit of the ISWI family of chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d386b65e70940fb41da7827c644e1dc0
http://hdl.handle.net/1721.1/109606
http://hdl.handle.net/1721.1/109606