Zobrazeno 1 - 10
of 151
pro vyhledávání: '"M, Crozier"'
Autor:
Jarrod Shilts, Thomas W M Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J D Greenwood, Samuel James Watson, Brian M Ortmann, Christian M Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A Nathan, Stefan Pöhlmann, Nicholas J Matheson, Paul J Lehner, Gavin J Wright
Publikováno v:
PLoS Biology, Vol 21, Iss 2, p e3001959 (2023)
The interactions between Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and human host factors enable the virus to propagate infections that lead to Coronavirus Disease 2019 (COVID-19). The spike protein is the largest structural compon
Externí odkaz:
https://doaj.org/article/b29561a147434b44ba62633c5cedb4fe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through direct binding to host receptors including ACE2. An alternate entry receptor for the virus was recently proposed to be basigin/CD147. These early stud
Externí odkaz:
https://doaj.org/article/985b50f6b24543619791a2c52c0f7f97
Autor:
Teresa, Brevini, Mailis, Maes, Gwilym J, Webb, Binu V, John, Claudia D, Fuchs, Gustav, Buescher, Lu, Wang, Chelsea, Griffiths, Marnie L, Brown, William E, Scott, Pehuén, Pereyra-Gerber, William T H, Gelson, Stephanie, Brown, Scott, Dillon, Daniele, Muraro, Jo, Sharp, Megan, Neary, Helen, Box, Lee, Tatham, James, Stewart, Paul, Curley, Henry, Pertinez, Sally, Forrest, Petra, Mlcochova, Sagar S, Varankar, Mahnaz, Darvish-Damavandi, Victoria L, Mulcahy, Rhoda E, Kuc, Thomas L, Williams, James A, Heslop, Davide, Rossetti, Olivia C, Tysoe, Vasileios, Galanakis, Marta, Vila-Gonzalez, Thomas W M, Crozier, Johannes, Bargehr, Sanjay, Sinha, Sara S, Upponi, Corrina, Fear, Lisa, Swift, Kourosh, Saeb-Parsy, Susan E, Davies, Axel, Wester, Hannes, Hagström, Espen, Melum, Darran, Clements, Peter, Humphreys, Jo, Herriott, Edyta, Kijak, Helen, Cox, Chloe, Bramwell, Anthony, Valentijn, Christopher J R, Illingworth, Bassam, Dahman, Dustin R, Bastaich, Raphaella D, Ferreira, Thomas, Marjot, Eleanor, Barnes, Andrew M, Moon, Alfred S, Barritt, Ravindra K, Gupta, Stephen, Baker, Anthony P, Davenport, Gareth, Corbett, Vassilis G, Gorgoulis, Simon J A, Buczacki, Joo-Hyeon, Lee, Nicholas J, Matheson, Michael, Trauner, Andrew J, Fisher, Paul, Gibbs, Andrew J, Butler, Christopher J E, Watson, George F, Mells, Gordon, Dougan, Andrew, Owen, Ansgar W, Lohse, Ludovic, Vallier, Fotios, Sampaziotis
Publikováno v:
Nature. 615:134-142
Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-converting enzyme 2 (ACE2)1, could represent a new chemoprophylactic approach for COVID-19 that complements vaccination2,3. However, the mechanisms that control t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d1f48c490c312e0492b836b250c36f
https://doi.org/10.1038/s41586-022-05594-0
https://doi.org/10.1038/s41586-022-05594-0
Autor:
Michele Tinti, Maria Lucia S. Güther, Thomas W. M. Crozier, Angus I. Lamond, Michael A. J. Ferguson
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Cellular proteins vary significantly in both abundance and turnover rates. These parameters depend upon their rates of synthesis and degradation and it is useful to have access to data on protein turnover rates when, for example, designin
Externí odkaz:
https://doaj.org/article/b1716ed1b9624d2eb356fb14dd688c86
Autor:
Eliciane C Mattos, Gisele Canuto, Nubia C Manchola, Rubens D M Magalhães, Thomas W M Crozier, Douglas J Lamont, Marina F M Tavares, Walter Colli, Michael A J Ferguson, Maria Júlia M Alves
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007103 (2019)
Trypanosoma cruzi, the etiological agent of Chagas' disease, affects 8 million people predominantly living in socioeconomic underdeveloped areas. T. cruzi trypomastigotes (Ty), the classical infective stage, interact with the extracellular matrix (EC
Externí odkaz:
https://doaj.org/article/9a2d59abface415f985f6452e9286cf4
Autor:
Ralph Junckerstorff, Tim M. Crozier, Chamila D M Liyanage, A. Amiruddin, Arunbalaji Muthusamy, Elizabeth Low, Blake P Mumford
Publikováno v:
Internal Medicine Journal. 52:599-604
Background Medical emergency team (MET) calls allow unstable patients to be identified earlier and enables clinicians to institute timely management to ameliorate physiological stress. Sinus tachycardia is a common cause for triggering MET calls. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab19d75b7d79bbff8652a615e5ceb60
https://doi.org/10.1111/imj.15093
https://doi.org/10.1111/imj.15093
Autor:
Tim M. Crozier, Matthew J Maiden, Irma Bilgrami, Rashmi B. Ghanpur, Emily Ys Huning, Graeme J Duke
Publikováno v:
Australian and New Zealand Journal of Obstetrics and Gynaecology. 60:548-554
BACKGROUND The incidence of severe acute maternal morbidity (SAMM) is one method of measuring the complexity of maternal health and monitoring maternal outcomes. Monitoring trends may provide a quantitative method for assessing health care at local,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5bd32bfb4ca44b401563919159b290
https://doi.org/10.1111/ajo.13103
https://doi.org/10.1111/ajo.13103
Autor:
Stefan Pöhlmann, Samuel James Watson, Markus Hoffmann, Edward J. D. Greenwood, Thomas W M Crozier, Paul J. Lehner, Gavin J. Wright, Tekle Pauzaite, Christian M. Gawden-Bone, James A. Nathan, Brian Ortmann, Jarrod Shilts, Ildar Gabaev, Ana Teixeira-Silva
SummaryThe interactions between severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and human host factors enable the virus to propagate infections that lead to COVID-19. The spike protein is the largest structural component of the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c745d2a09185fb2899e2caf0a429112f
https://doi.org/10.1101/2021.09.25.461776
https://doi.org/10.1101/2021.09.25.461776
Autor:
Edward J. D. Greenwood, Brian Ortmann, Paul J. Lehner, James A. Nathan, Frank McCaughan, Daniel Kottmann, Ravindra Mahadeva, Wenrui Guo, Linsey Porter, Thomas W M Crozier
Cigarette smoking has multiple serious negative health consequences. However, the epidemiological relationship between cigarette smoking and SARS-CoV-2 infection is controversial; and the interaction between cigarette smoking, airway expression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5f816399bcd216e9969ce18445f8342
https://doi.org/10.1101/2021.09.08.459428
https://doi.org/10.1101/2021.09.08.459428
Autor:
Olivia C. Tysoe, A Butler, Daniele Muraro, T. Brevini, Alfred Barritt, Sara Upponi, Gordon Dougan, Eleanor Barnes, R. E. Kuc, V. L. Mulcahy, Sally Forrest, Andrew Davenport, S. J. A. Buczacki, T. L. Williams, Ludovic Vallier, Mailis Maes, Paul Gibbs, S. Varankar, R. K. Gupta, Ansgar W. Lohse, George F. Mells, S. Baker, Christopher J.E. Watson, Andrew M. Moon, Kourosh Saeb-Parsy, P. Mlcochova, Sanjay Sinha, L. Swift, T. W. M. Crozier, M. Darvish-Damavandi, Susan E. Davies, Johannes Bargehr, M. Vila-Gonzalez, Gwilym J. Webb, William Gelson, F. Sampaziotis, Thomas Marjot, V. Galanakis, J. H. Lee, S. Dillon, Gareth Corbett
Publikováno v:
Oral.
Introduction The management of COVID19 is complicated by vaccine availability, the modest efficacy of existing treatments, and the potential for viral resistance. Therefore, there is a pressing need for new prophylactic and therapeutic agents. The vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac294d004b698ff6e4a55be518fa5174
https://doi.org/10.1136/gutjnl-2021-basl.7
https://doi.org/10.1136/gutjnl-2021-basl.7