Zobrazeno 1 - 10
of 688
pro vyhledávání: '"M, Biagini"'
Autor:
Stanley B. DeVore, Matthew Schuetz, Lauren Alvey, Henry Lujan, David E. Ochayon, Lindsey Williams, Wan Chi Chang, Alyssa Filuta, Brandy Ruff, Arjun Kothari, Jennifer M. Hahn, Eric Brandt, Latha Satish, Krishna Roskin, Andrew B. Herr, Jocelyn M. Biagini, Lisa J. Martin, Deniz Cagdas, Sevgi Keles, Joshua D. Milner, Dorothy M. Supp, Gurjit K. Khurana Hershey
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114589- (2024)
Summary: Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic impact on skin barrier homeostasis is largely unknown. CARD14 is known to signal via N
Externí odkaz:
https://doaj.org/article/93643c0fb9c04c9683a5cbbebc4dcd2e
Autor:
Mariana L. Stevens, Zhonghua Zhang, Elisabet Johansson, Samriddha Ray, Amrita Jagpal, Brandy P. Ruff, Arjun Kothari, Hua He, Lisa J. Martin, Hong Ji, Kathryn Wikenheiser-Brokamp, Matthew T. Weirauch, Dorothy M. Supp, Jocelyn M. Biagini Myers, Gurjit K. Khurana Hershey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Genetic variants in KIF3A are associated with atopic dermatitis (AD). Here, the authors identify two AD-risk alleles that show high methylation resulting in lower KIF3A expression. Mice with epidermis-specific loss of Kif3a show disrupted skin barrie
Externí odkaz:
https://doaj.org/article/cb73b4e6acf04165bd138a7fc4b88cd6
Autor:
Bahram Namjou, Michael Lape, Edyta Malolepsza, Stanley B. DeVore, Matthew T. Weirauch, Ozan Dikilitas, Gail P. Jarvik, Krzysztof Kiryluk, Iftikhar J. Kullo, Cong Liu, Yuan Luo, Benjamin A. Satterfield, Jordan W. Smoller, Theresa L. Walunas, John Connolly, Patrick Sleiman, Tesfaye B. Mersha, Frank D. Mentch, Hakon Hakonarson, Cynthia A. Prows, Jocelyn M. Biagini, Gurjit K. Khurana Hershey, Lisa J. Martin, Leah Kottyan
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:1086-1096
Asthma is the most common chronic condition in children and the third leading cause of hospitalization in pediatrics. The genome-wide association study catalog reports 140 studies with genome-wide significance. A polygenic risk score (PRS) with predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97618fd6bf814b05b895cae9f7c02cf
https://doi.org/10.1016/j.jaci.2022.03.035
https://doi.org/10.1016/j.jaci.2022.03.035
Autor:
Jordan Pennington, Erika Rasnick, Lisa J. Martin, Jocelyn M. Biagini, Tesfaye B. Mersha, Allison Parsons, Gurjit K. Khurana Hershey, Patrick Ryan, Cole Brokamp
Publikováno v:
American Journal of Health Promotion. 37:239-242
Purpose Quantify and examine the racial fairness of two widely used childhood asthma predictive precision medicine algorithms: the asthma predictive index (API) and the pediatric asthma risk score (PARS). Design Apply the API and PARS and evaluate mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5773d7a8c98b44257750e1b86b645cb5
https://doi.org/10.1177/08901171221121639
https://doi.org/10.1177/08901171221121639
Autor:
Elisabet Johansson, Seth Jenkins, Raphael Kopan, Gurjit K. Khurana Hershey, Xiaoting Chen, Jocelyn M. Biagini, John Kroner, Hua He, Liza Bronner Murrison, Xiaomeng Ren, Lisa J. Martin, Matthew T. Weirauch, Kristina Preusse
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine important in initiation of allergic inflammation. Single nucleotide polymorphisms (SNPs) in TSLP are associated with asthma, yet studies have shown inconsistent associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71794fa0e1df65de39027dea0c23a885
https://doi.org/10.1016/j.jaci.2021.05.033
https://doi.org/10.1016/j.jaci.2021.05.033
Autor:
Kieran J. Phelan, Kimberly A. Dill-McFarland, Arjun Kothari, R. Max Segnitz, Jeff Burkle, Brittany Grashel, Seth Jenkins, Daniel Spagna, Lisa J. Martin, David B. Haslam, Jocelyn M. Biagini, Maninder Kalra, Karen S. McCoy, Kristie R. Ross, Daniel J. Jackson, Tesfaye B. Mersha, Matthew C. Altman, Gurjit K. Khurana Hershey
Publikováno v:
Journal of Allergy and Clinical Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83bc9352979143430102d50ea1bf77e2
https://doi.org/10.1016/j.jaci.2023.02.031
https://doi.org/10.1016/j.jaci.2023.02.031
Autor:
Kirandeep Gill, Carolina Moore, Onyekachi Nwogu, John W. Kroner, Wan-Chi Chang, Mariana L. Stevens, Asel Baatyrbek kyzy, Jocelyn M. Biagini, Ashley L. Devonshire, Leah Kottyan, Justin T. Schwartz, Amal H. Assa’ad, Lisa J. Martin, Sandra Andorf, Gurjit K. Khurana Hershey, Krishna M. Roskin
Publikováno v:
bioRxiv
The skin is a major immune organ and skin barrier dysfunction is a major risk factor for the development of the inappropriate immune response seen in allergic disease. Skin barrier disruption alters the landscape of antigens experienced by the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a682df0fdc5217edee2ca2175eec2dfd
https://europepmc.org/articles/PMC9915585/
https://europepmc.org/articles/PMC9915585/
Autor:
Jaclyn W. McAlees, Theresa Baker, Lauren Houshel, Christopher McKnight, Andrew Lindsley, Richard T. Strait, Xue Zhang, Angela Cannata, Jocelyn M. Biagini, Melinda Butsch Kovacic, Ian P. Lewkowich
Publikováno v:
Clin Exp Allergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc07b6a270ffea60220e646d28c6b889
https://doi.org/10.1111/cea.14080
https://doi.org/10.1111/cea.14080
Autor:
Xue Zhang, Jocelyn M Biagini Myers, Veda K Yadagiri, Ashley Ulm, Xiaoting Chen, Matthew T Weirauch, Gurjit K Khurana Hershey, Hong Ji
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186150 (2017)
BACKGROUND:Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distingu
Externí odkaz:
https://doaj.org/article/9df3674e718e41458be6aa295221f17b
Autor:
Rachel L. Miller, Dan L. Nicolae, Fernando D. Martinez, Anne L. Wright, Robert F. Lemanske, Debra A. Stern, Suzanne Havstad, Eneida A. Mendonça, Dean Billheimer, Daniel J. Jackson, Ganesa Wegienka, Dennis R. Ownby, Lisa Gress, Carole Ober, James E. Gern, Jocelyn M. Biagini Myers, George T. O'Connor, Diane R. Gold, Lori Hoepner, Brian Hallmark, Gurjit K. Khurana Hershey
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 203:864-870
Rationale: Birth cohort studies have identified several temporal patterns of wheezing, only some of which are associated with asthma. Whether 17q12-21 genetic variants, which are closely associated...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a0ae712bd79ce9a7419dd049bdcf3d0
https://doi.org/10.1164/rccm.202003-0820oc
https://doi.org/10.1164/rccm.202003-0820oc