Zobrazeno 1 - 10
of 2 854
pro vyhledávání: '"M, BEST"'
Autor:
Shanna S. Leventhal, Thomas Bisom, Dean Clift, Deepashri Rao, Kimberly Meade-White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy Hinkley, Steven J. Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, Heinz Feldmann, David W. Hawman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic di
Externí odkaz:
https://doaj.org/article/a6d956186c9942bda98b2bc1f3d16cfd
Autor:
H. J. Jongen, M. Lipson, A. J. Teuling, S. Grimmond, J.‐J. Baik, M. Best, M. Demuzere, K. Fortuniak, Y. Huang, M. G. De Kauwe, R. Li, J. McNorton, N. Meili, K. Oleson, S.‐B. Park, T. Sun, A. Tsiringakis, M. Varentsov, C. Wang, Z.‐H. Wang, G. J. Steeneveld
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 16, Iss 10, Pp n/a-n/a (2024)
Abstract Urban Land Surface Models (ULSMs) simulate energy and water exchanges between the urban surface and atmosphere. However, earlier systematic ULSM comparison projects assessed the energy balance but ignored the water balance, which is coupled
Externí odkaz:
https://doaj.org/article/9c04ef63820540379e458ddace52ef10
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Additive manufacturing and electrospinning are widely used to create degradable biomedical components. This work presents important new data showing that the temperature used in accelerated tests has a significant impact on the degradation process in
Externí odkaz:
https://doaj.org/article/663abbd1ed48431eacc6db2c2d87e2f6
Autor:
Mahammad Gardashli, Max Baron, Charles Huang, Lee D. Kaplan, Zhipeng Meng, Dimitrios Kouroupis, Thomas M. Best
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The importance of mechanical loading and its relationship to orthobiologic therapies in the treatment of post-traumatic osteoarthritis (PTOA) is beginning to receive attention. This review explores the current efficacy of orthobiologic interventions,
Externí odkaz:
https://doaj.org/article/6a280f096c6c4ee0a69f4acfb77b47c3
Autor:
Xiaomin Cai, Christopher Warburton, Olivia F. Perez, Ying Wang, Lucy Ho, Christina Finelli, Quinn T. Ehlen, Chenzhou Wu, Carlos D. Rodriguez, Lee Kaplan, Thomas M. Best, Chun-Yuh Huang, Zhipeng Meng
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109983- (2024)
Summary: Recent studies have implicated a crucial role of Hippo signaling in cell fate determination by biomechanical signals. Here we show that mechanical loading triggers the activation of a Hippo-PKCζ-NFκB pathway in chondrocytes, resulting in t
Externí odkaz:
https://doaj.org/article/a5d261a63306466bb3727e2c0bbac1f2
Publikováno v:
Bioengineering, Vol 11, Iss 10, p 972 (2024)
In this review, we explore the intricate relationship between glucose metabolism and mechanotransduction pathways, with a specific focus on the role of the Hippo signaling pathway in chondrocyte pathophysiology. Glucose metabolism is a vital element
Externí odkaz:
https://doaj.org/article/90c3b19f95bc4edeaca9e6a39284f0d4
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Publikováno v:
Viruses, Vol 16, Iss 7, p 997 (2024)
The evolutionary pressures exerted by viral infections have led to the development of various cellular proteins with potent antiviral activities, some of which are known as antiviral restriction factors. TRIpartite Motif-containing protein 5 alpha (T
Externí odkaz:
https://doaj.org/article/984f30febf0b4e30a98e0c1aabbbc04a
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Autor:
Zachary Ripic, Michael Letter, Brandon Schoenwether, Lee D Kaplan, Michael G Baraga, Joseph P Costello Ii, Jordan Eskenazi, Molly Dennison, Thomas M Best, Joseph F Signorile, Moataz Eltoukhy
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0309003 (2024)
The purpose of this work was to provide a simple method to determine reactive strength during the 6-meter timed hop test (6mTH) and evaluate its association with isokinetic peak torque in patients following anterior cruciate ligament reconstruction (
Externí odkaz:
https://doaj.org/article/6efdac51765b47478613394a8643245b