Zobrazeno 1 - 10
of 114
pro vyhledávání: '"M, Aravagiri"'
Publikováno v:
Schizophrenia Bulletin. 17:197-216
There is enormous variation in plasma levels of most neuroleptics in patients on the same dose. Much of the past research on the relation between plasma levels of antipsychotic drugs and clinical change, however, has been difficult to interpret. It d
Autor:
M, Aravagiri, S R, Marder
Publikováno v:
Journal of mass spectrometry : JMS. 35(6)
A simple and highly sensitive liquid chromatographic/electrospray tandem mass spectrometric (LC/MS/MS) assay was developed for the simultaneous determination of risperidone (RSP) and its major circulating metabolite 9-hydroxyrisperidone (9-OH-RSP) in
Publikováno v:
Pharmaceutical research. 15(10)
Publikováno v:
Brain research. 704(2)
Chronic neuroleptic administration has previously been shown to alter in vivo measures of dopaminergic function and lead to regionally selective increases in neurotensin levels. In the current study, female rats were administered chronic haloperidol
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(1)
Previous studies have shown elevation of neurotensin neuromedin N (NT/N) and c-fos mRNA in the dorsolateral region of the rat neostriatum (DLSt) by acute administration of only typical antipsychotic drugs. However, NT/N mRNA in the nucleus accumbens-
Publikováno v:
The British journal of psychiatry. Supplement. (22)
Whereas some metabolites of antipsychotic drugs are psychoactive and contribute to clinical improvement, recent studies have provided evidence that certain metabolites contribute to side-effects which can be disabling enough to negate clinical improv
Autor:
T, Van Putten, B D, Marshall, R, Liberman, J, Mintz, T G, Kuehnel, L, Bowen, M, Aravagiri, S R, Marder
Publikováno v:
Psychopharmacology bulletin. 29(2)
Thirteen treatment-resistant, chronically institutionalized schizophrenic patients on high-dose neuroleptic (the equivalent of at least 50 mg of haloperidol (HPL) daily) were transferred to a special research ward for a trial of systematic dosage red
Publikováno v:
Psychopharmacology bulletin. 27(2)
Seventy-two newly readmitted, drug-free men with the diagnosis of schizophrenia by DSM-III were assigned randomly to receive fluphenazine hydrochloride at 5 mg, 10 mg, or 20 mg daily for 4 weeks. Fluphenazine (FLU), fluphenazine sulfoxide, 7-hydroxyf
Autor:
S R, Marder, T, Van Putten, M, Aravagiri, E M, Hawes, J W, Hubbard, G, McKay, J, Mintz, K K, Midha
Publikováno v:
Psychopharmacology bulletin. 26(2)
We monitored fluphenazine plasma levels in 39 schizophrenic patients who participated in a 2-year double-blind comparison of 5 mg and 25 mg of fluphenazine decanoate (FD) administered every 14 days. We investigated the relationship between log-transf
Publikováno v:
Schizophrenia Research. 4:290-291