Zobrazeno 1 - 10
of 389
pro vyhledávání: '"M, Ambrosini"'
Autor:
Itsuma Nagao, Minae Kawasaki, Takashi Goyama, Hyun Jung Kim, Douglas R. Call, Yoko M. Ambrosini
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT This study addresses the gap in translatable in vitro models for investigating Enterohemorrhagic E. coli (EHEC) infections, particularly relevant to both canine and human health. EHEC is known to induce acute colitis in dogs, leading to symp
Externí odkaz:
https://doaj.org/article/1690a78d71f949bdb0a017f0e7675cbc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Salmonella enterica serovar Dublin (S. Dublin) is an important enteric pathogen affecting cattle and poses increasing public health risks. Understanding the pathophysiology and host–pathogen interactions of S. Dublin infection are critical
Externí odkaz:
https://doaj.org/article/fd6d2aa597254634ad29e2efbe94e414
Autor:
Itsuma Nagao, Yoko M. Ambrosini
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Emerging evidence underscores the responsiveness of the mammalian intestine to dietary cues, notably through the involvement of LGR5 + intestinal stem cells in orchestrating responses to diet-driven signals. However, the effects o
Externí odkaz:
https://doaj.org/article/bbe4a50c409241a3ba9695114693cd6a
Autor:
G. Mazzoli, F. Nichetti, K. Shitara, R. Cohen, S. Lonardi, C. Cremolini, M.E. Elez, J. Chao, M. Fakih, S.J. Klempner, P. Jayachandran, S. Maron, D. Cowzer, L. Fornaro, L. Salvatore, V. Zhu, Y. Aoki, R. Cerantola, F. Bergamo, M. Salati, M. Ambrosini, G. Sabella, G. Randon, M.J. Overman, T. André, F. Pietrantonio
Publikováno v:
ESMO Gastrointestinal Oncology, Vol 3, Iss , Pp 100037- (2024)
Background: Programmed cell death protein 1 (PD-1) blockade improved the survival of patients with mismatch repair deficient (dMMR) and/or microsatellite instability-high (MSI-H) tumors, leading to tumor-agnostic approval of pembrolizumab in this pop
Externí odkaz:
https://doaj.org/article/0c37cc0360804ca5b240475f9112cdce
Accessible luminal interface of bovine rectal organoids generated from cryopreserved biopsy tissues.
Autor:
Minae Kawasaki, Yoko M Ambrosini
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0301079 (2024)
Developing precise species-specific in vitro models that closely resemble in vivo intestinal tissues is essential for advancing our understanding of gastrointestinal physiology and associated diseases. This is especially crucial in examining host-pat
Externí odkaz:
https://doaj.org/article/b8a974a629c54073899248f647f8aea9
Autor:
Soyoun Min, Nam Than, Yong Cheol Shin, Grace Hu, Woojung Shin, Yoko M. Ambrosini, Hyun Jung Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Here, we report a pathomimetic Leaky Gut Chip that recapitulates increased epithelial permeability and intestinal inflammation to assess probiotic intervention as live biotherapeutics. We leveraged a mechanodynamic human gut-on-a-chip (Gut C
Externí odkaz:
https://doaj.org/article/dbf8e70eea404d169e65e2c62ed6487d
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Autor:
Peter J. Welsh, Kaylyn McDaniel, Elizabeth W. Goldsmith, Joshua D. Ramsay, Alan Conley, Tina Jo Owen, Yoko M. Ambrosini, Michela Ciccarelli
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
A 1-year-old male intact Miniature Schnauzer mix was presented for chronic intermittent hematuria. Abdominal ultrasonography revealed a large, fluid-filled cystic structure extending cranially and dorsally to the prostate. Computed tomography scan im
Externí odkaz:
https://doaj.org/article/ed85c50d9606425d853cd3c1f15a77e7
Autor:
Itsuma Nagao, Yoko M. Ambrosini
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
The study of biliary physiology and pathophysiology has long been hindered by the lack of in vitro models that accurately reflect the complex functions of the biliary system. Recent advancements in 3D organoid technology may offer a promising solutio
Externí odkaz:
https://doaj.org/article/1e63b25cfef041228427fdcc84a4d566
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 966-975 (2022)
Abstract Background Serum concentrations of 25‐hydroxyvitamin D (25(OH)VD) and C‐reactive protein (CRP) and von Willebrand's factor (vWF) concentration correlate with histopathologic disease grade and stage in chronic inflammatory and fibrotic he
Externí odkaz:
https://doaj.org/article/857977c9dfed4a12834d74579ef5943c