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Publikováno v:
Journal of Applied Chemistry. 12:217-225
Publikováno v:
Journal of Applied Chemistry. 12:230-234
The solid-solid reaction between potassium perchlorate and a crosslinked divinylbenzene–ethylstyrene copolymer was studied under various conditions of temperature, compounding pressure, grain size and reactant ratio. The same reaction was also inve
Publikováno v:
The Journal of Immunology. 161:3536-3542
It was recently reported that human and mouse melanoma cells express Fas ligand (FasL) but almost no Fas, which may contribute to their immune privilege. AS101 (ammonium trichloro(dioxoethylene-0,0′)tellurate), a synthetic immunomodulator with mini
Publikováno v:
The Journal of Immunology. 159:2658-2667
It has recently been found that in systemic lupus erythematosus (SLE), a multisystem inflammatory disorder characterized by autoantibody production and decreased cellular immune response, increased spontaneous production of IL-10 occurs. The immunomo
Publikováno v:
The Journal of Immunology. 156:1101-1109
The immunomodulator ammonium trichloro(dioxyethylene-0-0')tellurate (AS101) has been shown to possess antitumoral properties in several murine models. In the present study, we demonstrate a synergistic in vivo antitumor effect of AS101 and Taxol agai
Publikováno v:
The British journal of dermatology. 158(3)
The immunomodulator AS101 [ammonium trichloro (dioxoethylene-O,O') tellurate], a nontoxic tellurium (IV) compound, has antitumoral effects which were demonstrated in several preclinical and clinical studies.To investigate the antitumour activity of A
Publikováno v:
Clinical and Experimental Immunology. 79:443-447
SUMMARY The role of the synthetic immunomodulator AS101 on the production of interleukin-2 (IL-2) by spleen cells of mice with SLE was investigated BALB/c female mice, in which SLE was induced by immunization with the pathogenic idiotype of anti-DNA
Autor:
B, Sredni, R H, Xu, M, Albeck, U, Gafter, R, Gal, A, Shani, T, Tichler, J, Shapira, I, Bruderman, R, Catane, B, Kaufman, J K, Whisnant, K L, Mettinger, Y, Kalechman
Publikováno v:
International journal of cancer. 65(1)
The immunomodulator AS101 has been demonstrated to exhibit radioprotective and chemoprotective effects in mice. Following phase-I studies, preliminary results from phase-II clinical trials on non-small-cell-lung-cancer patients showed a reduction in
The cytoprotective effect of the immunomodulator AS101 against hydrochloride induced gastric lesions
Publikováno v:
Research communications in molecular pathology and pharmacology. 87(1)
AS101 as a new immunomodulator has been shown to induce production of a variety of cytokines such as interleukin-1, interleukin-2, colony-stimulating factor, interferon-gamma and tumor necrosis factor, and demonstrate a potential chemo-protection fro