Severe Acute Respiratory Syndrome Coronavirus 2 Seroassay Performance and Optimization in a Population With High Background Reactivity in Mali

Autor: M'Bouye Doucoure, Jennifer Kwan, John Woodford, Irfan Zaidi, Justin Doritchamou, Jaroslav Holly, Kaitlyn Sadtler, Patrick E. Duffy, Alassane Dicko, Nada Alani, Amatigue Zeguime, Dominic Esposito, Jonathan P. Renn, Maryonne Snow-Smith, Ivan Kosik, Issaka Sagara, Jonathan W. Yewdell

Publikováno v: The Journal of Infectious Diseases. 224:2001-2009

Background False positivity may hinder the utility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological tests in sub-Saharan Africa. Methods From 312 Malian samples collected before 2020, we measured antibodies to the commonly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ced5aa30d6d2800cbc4724e4b9ee06e8
https://doi.org/10.1093/infdis/jiab498

Rapidly Increasing Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence and Limited Clinical Disease in 3 Malian Communities: A Prospective Cohort Study

Autor: Mamady Kone, Mahamadoun H. Assadou, Rathy Mohan, Jacquelyn Lane, Jennifer Kwan, John Woodford, Patrick E. Duffy, Justin Doritchamou, Dominic Esposito, Emily Higbee, Alassane Dicko, Kaitlyn Sadtler, Oumar Attaher, Irfan Zaidi, M'Bouye Doucoure, Issaka Sagara, Amatigue Zeguime, Abdoulaye Katile

Publikováno v: Clinical Infectious Diseases
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, pp.ciab589. ⟨10.1093/cid/ciab589⟩
medRxiv

BACKGROUND: The extent of SARS-CoV-2 exposure and transmission in Mali and the surrounding region is not well understood, although infection has been confirmed in nearly 14,000 symptomatic individuals and their contacts since the first case in March

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3937fa4871ddd8694810f7ce9467e38a
https://www.hal.inserm.fr/inserm-03452012/file/ciab589.pdf

SARS-CoV-2 seroassay optimization and performance in a population with high background reactivity in Mali

Autor: Ivan Kosik, Jennifer Kwan, Dominic Esposito, Justin Doritchamou, Jonathan W. Yewdell, John Woodford, Alassane Dicko, Patrick E. Duffy, Nada Alani, Kaitlyn Sadtler, Irfan Zaidi, Issaka Sagara, Jonathan P. Renn, Jaroslav Holly, Amatigue Zeguime, Maryonne Snow-Smith, M'Bouye Doucoure

Publikováno v: The Journal of Infectious Diseases
medRxiv

Serological tests are an indispensable tool to understand the epidemiology of the SARS-CoV-2 pandemic, particularly in areas where molecular diagnostics are limited. Poor assay performance may hinder the utility of these tests, including high rates o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8503bfef7fb006683320548f46f94a
https://doi.org/10.1101/2021.03.08.21252784

Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults

Autor: Erin E. Gabriel, Ibrahima Baber, Mahamadoun H. Assadou, M'Bouye Doucoure, Rathy Mohan, Olga Muratova, Sekou F. Traore, David L Jones, Charles Anderson, Intimbeye Tembine, Karamoko Niaré, Nicholas J. MacDonald, David L. Narum, Mamady Kone, Mamadou B. Coulibaly, Kelly M. Rausch, Michael P. Fay, Issaka Sagara, Daming Zhu, Sara A. Healy, Ogobara K. Doumbo, Yimin Wu, Merepen A. Guindo, Amagana Dolo, Kourane Sissoko, Patrick E. Duffy

Publikováno v: The Lancet Infectious Diseases
The Lancet Infectious Diseases, New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-, 2018, 18 (9), pp.969-982. ⟨10.1016/S1473-3099(18)30344-X⟩

International audience; BACKGROUND:Pfs25H-EPA is a protein-protein conjugate transmission-blocking vaccine against Plasmodium falciparum that is safe and induces functional antibodies in malaria-naive individuals. In this field trial, we assessed Pfs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5a97b3c9ef9135200a0dc5bf6607dc
https://doi.org/10.1016/s1473-3099(18)30344-x