Bioinformatics and molecular biology tools for diagnosis, prevention, treatment and prognosis of COVID-19

Autor: Débora Dummer Meira, Aléxia Stefani Siqueira Zetum, Matheus Correia Casotti, Danielle Ribeiro Campos da Silva, Bruno Cancian de Araújo, Creuza Rachel Vicente, Daniel de Almeida Duque, Bianca Paulino Campanharo, Fernanda Mariano Garcia, Camilly Victória Campanharo, Carla Carvalho Aguiar, Carolina de Aquino Lapa, Flávio dos Santos Alvarenga, Henrique Perini Rosa, Luiza Poppe Merigueti, Marllon Cindra Sant’Ana, Clara W.T. Koh, Raquel Furlani Rocon Braga, Rahna Gonçalves Coutinho da Cruz, Rhana Evangelista Salazar, Vinícius do Prado Ventorim, Gabriel Mendonça Santana, Thomas Erik Santos Louro, Luana Santos Louro, Flavia Imbroisi Valle Errera, Flavia de Paula, Lorena Souza Castro Altoé, Lyvia Neves Rebello Alves, Raquel Silva dos Reis Trabach, Eldamária de Vargas Wolfgramm dos Santos, Elizeu Fagundes de Carvalho, Kuan Rong Chan, Iúri Drumond Louro

Publikováno v: Heliyon, Vol 10, Iss 14, Pp e34393- (2024)

Since December 2019, a new form of Severe Acute Respiratory Syndrome (SARS) has emerged worldwide, caused by SARS coronavirus 2 (SARS-CoV-2). This disease was called COVID-19 and was declared a pandemic by the World Health Organization in March 2020.

Externí odkaz: https://doaj.org/article/a6ae0b1c5da84082a3dd25841bdbb608

Investigation of maternal polymorphisms in genes related to glucose homeostasis and the influence on birth weight: a cohort study1

Autor: Lyvia Neves Rebello Alves, Marcos Pereira, Jéssica Aflávio dos Santos, Eldamária de Vargas Wolfgramm dos Santos, Gisele Queiroz Carvalho, Jerusa da Mota Santana, Eric Arrivabene Tavares, Marcilio Delan Baliza Fernandes, Djanilson Barbosa dos Santos, Iúri Drumond Louro

Publikováno v: Jornal de Pediatria, Vol 98, Iss 3, Pp 296-302 (2022)

Objectives: To contribute to a better understanding of the maternal genetic mechanisms that influence obstetric outcomes and that are involved in maternal and child health, this study aimed to evaluate the association between maternal genetic variant

Externí odkaz: https://doaj.org/article/e41c6436fd78449b928aead997d66e03

Hypermethylation status of DAPK, MGMT and RUNX3 in HPV negative oral and oropharyngeal squamous cell carcinoma

Autor: Raquel Silva dos Reis, Jéssica Aflávio dos Santos, Priscila Marinho de Abreu, Raquel Spinassé Dettogni, Eldamária de Vargas Wolfgramm dos Santos, Elaine Stur, Lidiane Pignaton Agostini, Quézia Silva Anders, Lyvia Neves Rebello Alves, Isabella Bittencourt do Valle, Marília Arantes Lima, Evandro Duccini Souza, José Roberto Vasconcelos de Podestá, Sandra Ventorin von Zeidler, Melissa de Freitas Cordeiro-Silva, Iúri Drumond Louro

Publikováno v: Genetics and Molecular Biology, Vol 43, Iss 3 (2020)

Abstract Squamous cell carcinoma of the oral cavity and oropharynx is the sixth most common type of cancer in the world. During tumorigenesis, gene promoter hypermethylation is considered an important mechanism of transcription silencing of tumor sup

Externí odkaz: https://doaj.org/article/96f24bf2aa254582852e58a0f8128260

Computational Biology Helps Understand How Polyploid Giant Cancer Cells Drive Tumor Success

Autor: Matheus Correia Casotti, Débora Dummer Meira, Aléxia Stefani Siqueira Zetum, Bruno Cancian de Araújo, Danielle Ribeiro Campos da Silva, Eldamária de Vargas Wolfgramm dos Santos, Fernanda Mariano Garcia, Flávia de Paula, Gabriel Mendonça Santana, Luana Santos Louro, Lyvia Neves Rebello Alves, Raquel Furlani Rocon Braga, Raquel Silva dos Reis Trabach, Sara Santos Bernardes, Thomas Erik Santos Louro, Eduardo Cremonese Filippi Chiela, Guido Lenz, Elizeu Fagundes de Carvalho, Iúri Drumond Louro

Publikováno v: Genes. 14:801

Precision and organization govern the cell cycle, ensuring normal proliferation. However, some cells may undergo abnormal cell divisions (neosis) or variations of mitotic cycles (endopolyploidy). Consequently, the formation of polyploid giant cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe7dc18873e00c358f2383d5f9693a44
https://doi.org/10.3390/genes14040801

Hypermethylation status of DAPK, MGMT and RUNX3 in HPV negative oral and oropharyngeal squamous cell carcinoma

Autor: Lyvia Neves Rebello Alves, Raquel Silva dos Reis, Marília Arantes Lima, Eldamária de Vargas Wolfgramm dos Santos, Sandra Ventorin Von Zeidler, Melissa de Freitas Cordeiro-Silva, Quézia Silva Anders, Jéssica Aflávio dos Santos, Isabella Bittencourt do Valle, José Roberto Vasconcelos de Podestá, Elaine Stur, Priscila Marinho de Abreu, Raquel Spinassé Dettogni, Lidiane Pignaton Agostini, Iúri Drumond Louro, Evandro Duccini Souza

Publikováno v: Genetics and Molecular Biology, Volume: 43, Issue: 3, Article number: e20190334, Published: 21 AUG 2020
Genetics and Molecular Biology, Vol 43, Iss 3 (2020)
Genetics and Molecular Biology
Genetics and Molecular Biology v.43 n.3 2020
Sociedade Brasileira de Genética (SBG)
instacron:SBG

Squamous cell carcinoma of the oral cavity and oropharynx is the sixth most common type of cancer in the world. During tumorigenesis, gene promoter hypermethylation is considered an important mechanism of transcription silencing of tumor suppressor g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e63bb7f1e251e9b415df0d4ea3f1ac
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000500108&lng=en&tlng=en