Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lyudmyla M Antypenko"'
Autor:
Oleksii M. Antypenko, Lyudmyla M. Antypenko, Sergiy I. Kovalenko, Andrey M. Katsev, Olena M. Achkasova
Publikováno v:
Arabian Journal of Chemistry, Vol 9, Iss 6, Pp 792-805 (2016)
The death rate from cancer and infectious diseases is still very high, therefore research in this area is extremely important and promising as in medical, so in economic point of view. Thus, potassium salt of tetrazolo[1,5-c]quinazolin-5-thion was mo
Externí odkaz:
https://doaj.org/article/4dba385302d148c18f0a04a0dcdaba1a
Publikováno v:
Acta Chimica Slovenica, Vol 66, Iss 4, Pp 784-791 (2019)
Tacrolimus (FK506) is an immunosuppressant drug widely used to avoid organ rejection in transplant patients. It has a profound influence on the cellular stress response by interfering with the calmodulin-calcineurin signaling pathway. In this context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246e59036562d62be0788176b5ab3a3
https://journals.matheo.si/index.php/ACSi/article/view/4723
https://journals.matheo.si/index.php/ACSi/article/view/4723
Autor:
Fatuma A. Hassan, Zhanar Sadykova, Leif-Alexander Garbe, Lyudmyla M. Antypenko, Karl G. Steffens
Publikováno v:
Acta Chimica Slovenica, Vol 65, Iss 4, Pp 836-841 (2018)
Antifungal activity of suberic acid monomethyl ester (monomethyl suberate) was investigated in a growth inhibition assay comprising of 11 different fungi and 3 Phytophthora oomycetes strains relevant in agriculture. In comparison to standard antifung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fc0b328932226af80f9377b1041df6
https://doi.org/10.17344/acsi.2018.4440
https://doi.org/10.17344/acsi.2018.4440
Publikováno v:
Dhaka University Journal of Pharmaceutical Sciences. 16:37-42
A simple and low-cost UV-spectrophotometric method has been developed and validated for the quantification of Octopirox in bulk. The linearity was found at 307 ± 1 nm in 10-50 ?g/ml solution of ethanol-water (1:3, v:v) with r2 = 0.99. The limit of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006ed2ea206494711a25e5aae5dc0b6d
https://doi.org/10.3329/dujps.v16i1.33380
https://doi.org/10.3329/dujps.v16i1.33380
Autor:
Lyudmyla M. Antypenko, Sergiy Kovalenko, Oleksii M. Antypenko, Konstantin P. Schabelnyk, S. V. Kholodnyak
Publikováno v:
Chemistry of Heterocyclic Compounds. 53:292-309
This review offers summary and analysis of the data on the synthesis of 2-(azolyl)anilines published from 1942 to 2016. It is shown, that they act as effective 1,5-nucleophiles in cyclocondensation reactions. Besides, biological activity data on 2-(a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43dfc03a9bc919986e32b4f7bbaa2ce3
https://doi.org/10.1007/s10593-017-2051-7
https://doi.org/10.1007/s10593-017-2051-7
Autor:
Lyudmyla M. Antypenko, Leif-Alexander Garbe, Karl G. Steffens, Fatuma Meyer, Sergiy Kovalenko, Kostiantyn Shabelnyk, Vera Meyer, Zhanar Sadykova
Publikováno v:
Archiv der Pharmazie. 352(10)
Due to their high specificity and efficacy, triazoles have become versatile antifungals to treat fungal infections in human healthcare and to control phytopathogenic fungi in agriculture. However, azole resistance is an emerging problem affecting hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b696f0bc4b92ec10f405540304c31fa
https://pubmed.ncbi.nlm.nih.gov/31463959
https://pubmed.ncbi.nlm.nih.gov/31463959
Publikováno v:
Journal of Heterocyclic Chemistry. 54:1267-1278
Enduring the novel effective antimicrobial agents search, N-(phenyl, benzyl, hetaryl)-2-([1,2,4]triazolo[1,5-c]quinazolin-2-ylthio)acetamides were synthesized, evaluated for structure (LC-MS, IR, 1H-NMR spectra and elemental analysis), and investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a5007ee6ce05099b1c94624d3d67c2
https://doi.org/10.1002/jhet.2702
https://doi.org/10.1002/jhet.2702
Autor:
Oleksii M. Antypenko, Sergiy Kovalenko, Vladyslav O. Nikitin, Lyudmyla M. Antypenko, Oleksandr V. Karpenko
Publikováno v:
Helvetica Chimica Acta. 99:621-631
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01259cd90d54db7f1c8a3c55c5a6c0eb
https://doi.org/10.1002/hlca.201600062
https://doi.org/10.1002/hlca.201600062
Autor:
S. I. Kovalenko, V. M. Shvets, Lyudmyla M. Antypenko, O. Yu. Voskoboynik, G. G. Berest, I. S. Nosulenko, O. V. Krivoschey
Publikováno v:
Vìsnik farmacìï. :54-58
It has been found that 6-[(b-dialkylaminoethylthio]-3-R-2H-[1,2,4]triazino[2,3-c]quinazolin-2-ones exhibit the antiviral activity against respiratory and the biodefence virus panel (EC50 3.2-36.0 mg/ml) and the influenza type A and B (EC50 1.1-18.0 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73afb06e8abb2adbebf0826fbc7c6e61
https://doi.org/10.24959/nphj.16.2093
https://doi.org/10.24959/nphj.16.2093
Autor:
Lyudmyla M. Antypenko, Sergiy Kovalenko, Andrew M. Katsev, Volodymyr Novikov, Natalia S. Fedyunina, Oleksandr Karpenko
Publikováno v:
Current Computer Aided-Drug Design. 12:29-41
The increasing mortality due to antibacterial resistance necessitates the search for novel antimicrobial agents. Hence, series of 1-R-2-([1,2,4]triazolo[1,5-c]quinazoline-2-ylthio)etanon(ol)s were synthesized, evaluated by spectral data and studied a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b5206e283c15629a8486263c7b1b610
https://doi.org/10.2174/1573409912666160126142236
https://doi.org/10.2174/1573409912666160126142236