Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lyudmila Sikora"'
Publikováno v:
Experimental Lung Research. 35:119-135
Exposure to environmental tobacco smoke (ETS) is known to contribute to and exacerbate inflammatory diseases of the lung such as chronic obstructive pulmonary disease (COPD) and asthma. The effect of ETS on angiogenesis and leukocyte recruitment, bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c1671828e67109068b56ceb8099c2b
https://doi.org/10.1080/01902140802449729
https://doi.org/10.1080/01902140802449729
Autor:
Nooshin S. Bahaie, P. Sriramarao, Lyudmila Sikora, Riaz I. Zuberi, Zhuangzhi Wang, Fu-Tong Liu, Savita P. Rao, Bruce L. Zuraw
Publikováno v:
The Journal of Immunology. 179:7800-7807
Allergic inflammation involves the mobilization and trafficking of eosinophils to sites of inflammation. Galectin-3 (Gal-3) has been shown to play a critical role in eosinophil recruitment and airway allergic inflammation in vivo. The role played by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a00e1956011044ed23ed651a11f3a47
https://doi.org/10.4049/jimmunol.179.11.7800
https://doi.org/10.4049/jimmunol.179.11.7800
Autor:
Lyudmila Sikora, Savita P. Rao, K.R. O'Neill, R.S. Pero, Michael T. Borchers, Hiam Abdala-Valencia, H.H. Shen, Sergei I. Ochkur, Karsten Spicher, Melvin I. Simon, Lutz Birnbaumer, Michael P. McGarry, Nancy A. Lee, James J. Lee, P. Sriramarao, Joan M. Cook-Mills
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4371-4376
The trafficking of leukocytes from the blood to sites of inflammation is the cumulative result of receptor-ligand-mediated signaling events associated with the leukocytes themselves as well as with the underlying vascular endothelium. Our data show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f743ac49b81312ef506b832fe3f25e
https://doi.org/10.1073/pnas.0700185104
https://doi.org/10.1073/pnas.0700185104
Publikováno v:
STEM CELLS. 24:2373-2381
The effect of sustained exposure to nicotine, a major constituent of cigarette smoke, on hematopoiesis in the bone marrow (BM) and spleen was evaluated in a murine model. BALB/c mice were exposed to nicotine subcutaneously using 21-day slow-release p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7753290d2c418fa6d666e6063c4e07
https://doi.org/10.1634/stemcells.2005-0447
https://doi.org/10.1634/stemcells.2005-0447
Autor:
Lyudmila Sikora, Ingrid U. Schraufstatter, P. Sriramarao, Bruce L. Zuraw, Richard G. DiScipio
Publikováno v:
International Immunopharmacology. 6:1109-1118
Matrix metalloproteinase 9 (MMP-9) is a crucial proteinase, utilized by both eosinophils and neutrophils, that mediates transmigration through extracellular basement membranes. We have found that neutralization of MMP-9 by a monoclonal antibody or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a52c8c953463543600830dd98ab6d04
https://doi.org/10.1016/j.intimp.2006.02.006
https://doi.org/10.1016/j.intimp.2006.02.006
Autor:
Lyudmila Sikora, Francisco M. Lio, Savita P. Rao, Karine Lavrador, Terlika S. Pandit, P. Sriramarao, Stefen A. Boehme
Publikováno v:
The Journal of Immunology. 173:3599-3603
Elevated levels of serotonin (5-hydroxytryptamine, 5-HT) are observed in the serum of asthmatics. Herein, we demonstrate that 5-HT functions independently as an eosinophil chemoattractant that acts additively with eotaxin. 5-HT2A receptor antagonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6672a3eefa308e02945b90165894300c
https://doi.org/10.4049/jimmunol.173.6.3599
https://doi.org/10.4049/jimmunol.173.6.3599
Publikováno v:
The American Journal of Pathology. 164:1183-1190
Efforts to treat tumors have routinely depended on disruption of cell proliferation by a variety of methods, many involving stimulation of apoptosis. We have previously shown that a truncated form of 24-kd basic fibroblast growth factor consisting of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc38dd8166e0e6fcb7542ee3ae725c9
https://doi.org/10.1016/s0002-9440(10)63206-3
https://doi.org/10.1016/s0002-9440(10)63206-3
Autor:
Ingrid U. Schraufstatter, P. Sriramarao, Hiroshi Takamori, Richard G. DiScipio, Lyudmila Sikora
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L494-L501
Pulmonary and activation-regulated chemokine (PARC/CCL18) belongs to the family of CC chemokines and shares 61% sequence identity with monocyte inflammatory protein (MIP)-1α. Produced by dendritic cells and macrophages primarily in the lung, PARC is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7ffe0b6ee6cce9bccb8033eedaa081
https://doi.org/10.1152/ajplung.00323.2002
https://doi.org/10.1152/ajplung.00323.2002
Autor:
David H. Broide, Savita P. Rao, Lyudmila Sikora, P. Sriramarao, Greg K. Hughes, Åsa Johansson
Publikováno v:
The American Journal of Pathology. 162:2019-2028
The cascade of leukocyte interactions under conditions of blood flow is well established in the systemic microcirculation, but not in lung microcirculation. We have developed a murine model to study lung microcirculation by transplanting lung tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579759ee4f7a639ba18b5c2eca7093fd
https://doi.org/10.1016/s0002-9440(10)64334-9
https://doi.org/10.1016/s0002-9440(10)64334-9
Publikováno v:
Blood. 101:863-868
The differentiation of eosinophils from hematopoietic precursors and their subsequent maturation, chemotaxis, and activation is primarily regulated by interleukin-5 (IL-5). To examine the effect of chronic IL-5 exposure on hematopoiesis, IL-5 transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ad78571b3bd962613c8282e73ac7a7
https://doi.org/10.1182/blood-2002-03-0735
https://doi.org/10.1182/blood-2002-03-0735