Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lyudmila Kancheva"'
Autor:
Antonín Pařízek, Jana Kubátová, Eva Králíková, Beata Racz, Martin Hill, M Salátová, Veronika Cirmanova, Lyudmila Kancheva, Michaela Duskova, Marta Velíková, Hana Pospisilova, H. Kazihnítková, Kateřina Šimůnková, Luboslav Stárka, Hana Hruskovicova
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Chronic smoking alters the circulating levels of sex hormones and possibly also the neuroactive steroids. However, the data available is limited. Therefore, a broad spectrum of free and conjugated steroids and related substances was quantified by GC-
Autor:
Lucie, Sosvorova, Radmila, Kanceva, Josef, Vcelak, Lyudmila, Kancheva, Milan, Mohapl, Luboslav, Starka, Eva, Havrdova
Publikováno v:
Neuro endocrinology letters. 36(6)
Cytokine production and immune activation are associated with various pathological conditions including neurodegenerative disorders. One of them is multiple sclerosis (MS), known autoimmune disease. Inflammatory changes were also reported in normal p
Autor:
Antonín Pařízek, Jana Kubátová, Martin Hill, Jana Vrbikova, Petr Marusic, Lyudmila Kancheva, Marta Velíková, Jana Zárubová, Michaela Duskova, Luboslav Stárka, Radmila Kancheva
Publikováno v:
Steroids. 76:1351-1357
Epilepsy in women may be associated with reproductive disorders and alterations in serum steroid levels. Some steroids can be induced by epilepsy and/or treatment with antiepileptic drugs; however, there are still limited data available concerning th
Autor:
Martin Hill, Lyudmila Kancheva, Luboslav Stárka, Zdenek Novak, Jan Chrastina, Radmila Kancheva
Publikováno v:
Neuroscience. 191:22-27
Some peripheral steroids penetrate the blood-brain barrier (BBB), providing at least substances for the CNS steroid metabolome. That is why the predictive value of the peripheral steroids appears to be comparable with that of the cerebrospinal fluid
Autor:
Petr Marusic, Michaela Duskova, Marta Velíková, Luboslav Stárka, Jana Kubátová, Kateřina Šimůnková, Jana Vrbikova, Radmila Kancheva, Martin Hill, Lyudmila Kancheva, Ludmila Zamrazilová, H. Kazihnítková, Jana Zárubová
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 122:239-252
Only limited data is available concerning the role of unconjugated Δ 5 C19-steroids and almost no data exists regarding the neuroactive C21 and C19 3α-hydroxy-5α/β-metabolites in men with epilepsy. To evaluate the alterations in serum neuroactive
Autor:
Luboslav Stárka, Marta Velíková, Radmila Kancheva, Ivo Říha, Jan Chrastina, Zdeněk Novák, Martin Hill, Lyudmila Kancheva
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 119:35-44
To compare the predictivity of the neuroactive steroids in the cerebrospinal fluid and peripheral blood for the diagnostics of CNS disturbances, eighteen unconjugated steroids were quantified in the cerebrospinal fluid (CSF) from the 3rd ventricle an
Autor:
Jana Vrbikova, Lyudmila Kancheva, Terezie Pelikanova, Helena Včeláková, Luboslav Stárka, Martin Hill
Publikováno v:
Steroids. 72:792-801
Certain androstane steroids (AS) modulate ionotropic receptors, as do the pregnane steroids. Whereas women produce significant amounts of neuroactive progesterone metabolites, the steroid neuromodulators in men originate mainly from the 3-oxo-4-ene C
Autor:
Antonin Parizek, Radmila Kancheva, Martin Hill, Helena Havlíková, Luboslav Stárka, Tomas Fait, Lyudmila Kancheva, David Cibula
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 105:166-175
This study addresses the question of whether changes in the biosynthesis and metabolism of neuroactive pregnanolone isomers (PIs) might participate in the timing of parturition in humans. The time profiles of unconjugated allopregnanolone (3alpha-hyd
Autor:
Vladimír Pouzar, Lyudmila Kancheva, Jana Vrbikova, Luboslav Stárka, Martin Hill, Radmila Kancheva, Ivan Černý, Helena Havlíková
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 96:187-200
7-Hydroxy-metabolites of dehydroepiandrosterone (DHEA) and 3beta,17beta-androstenediol (AD) possess immunomodulatory and neuroprotective properties; therefore, the measurement of these steroids in patients with autoimmune diseases or disturbances in