Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Lysyl oxidase Lox"'
Autor:
Yingbiao Wu, Jun Luo, Xiang Song, Wei Gu, Saihua Wang, Shuwen Hao, Zhiwu Dong, Zhongping Ning
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 6, Pp 717-724 (2023)
Objective(s): Irisin was reported as a cardioprotective and anti-oxidative effector, while the effect on atrial fibrosis is unknown. The current research examined irisin’s function in atrial fibrillation (AF); atrial fibrosis brought on by Ang II c
Externí odkaz:
https://doaj.org/article/571f43e1b9854853addbfd8eed302156
Publikováno v:
European Cells & Materials, Vol 43, Pp 130-152 (2022)
Tendons are collagen-rich musculoskeletal tissues that possess the mechanical strength needed to transfer forces between muscles and bones. The mechanical development and function of tendons are impacted by collagen crosslinks. However, there is a li
Externí odkaz:
https://doaj.org/article/b9db7d5185b442709369d3023f1a5987
Akademický článek
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Autor:
Aitao Nai, Huihui Zeng, Qiong Wu, Zirui He, Shuwen Zeng, Shoaib Bashir, Feng Ma, Jie He, Wei Wan, Meng Xu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Gastric carcinoma is the fourth most prevalent cause of cancer-related deaths worldwide because of dismal prognosis and few therapeutic options. Accumulated studies have indicated that targeting lysyl oxidase (LOX) family members may serve as an anti
Externí odkaz:
https://doaj.org/article/0e3c1158dc53460890ec76a62f22b262
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1563 (2022)
Vascular smooth muscle cells (VSMCs) are the main stromal cells in the medial layer of the vascular wall. These cells produce the extracellular matrix (ECM) and are involved in many pathological changes in the vascular wall. Semicarbazide-sensitive a
Externí odkaz:
https://doaj.org/article/c862ab248cf44c07b9808abe8d60a3fc
Akademický článek
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Autor:
Rozalia Laczko, Katalin Csiszar
Publikováno v:
Biomolecules, Vol 10, Iss 8, p 1093 (2020)
Cu-dependent lysyl oxidase (LOX) plays a catalytic activity-related, primary role in the assembly of the extracellular matrix (ECM), a dynamic structural and regulatory framework which is essential for cell fate, differentiation and communication dur
Externí odkaz:
https://doaj.org/article/a8de0fbb99054085beea9cbcd5ae2762
Akademický článek
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Publikováno v:
Biomolecules; Volume 12; Issue 11; Pages: 1563
Vascular smooth muscle cells (VSMCs) are the main stromal cells in the medial layer of the vascular wall. These cells produce the extracellular matrix (ECM) and are involved in many pathological changes in the vascular wall. Semicarbazide-sensitive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab0967a31d43bc038f48a55b8bfe609
https://hdl.handle.net/2086/22262
https://hdl.handle.net/2086/22262
Autor:
Pelin Gülizar Ersan, Fatma Gundogdu, Aysegul Uner, Vitali Sikirzhytski, Unal Metin Tokat, Aysegul Kaymak, Phillip Buckhaults, Hayriye Tatlı Doğan, Gamze Aykut, Carolyn E. Banister, Kemal Kosemehmetoglu, Omer Dizdar, Suhail A. Ansari, Umar Raza, Mehmet Dogan, Ozge Saatci, Ozgur Sahin, Aynur Isik, Ozge Akbulut, Sercan Aksoy, Aytekin Akyol, Yasser Riazalhosseini, Pouria Jandaghi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Chemoresistance is a major obstacle in triple negative breast cancer (TNBC), the most aggressive breast cancer subtype. Here we identify hypoxia-induced ECM re-modeler, lysyl oxidase (LOX) as a key inducer of chemoresistance by developing chemoresist