Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung

Autor: Mario P. Tschan, Anna M. Schläfli, Sabina Berezowska, Ralph A. Schmid, Tereza Losmanová, Magali Humbert, Félice A. Janser, Rupert Langer, Christina Neppl, Igor Tokarchuk

Publikováno v: Oxidative Medicine and Cellular Longevity
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Oxidative medicine and cellular longevity, vol. 2020, pp. 8506572
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)

LAMP2A and HSC70 are crucial players in chaperone-mediated autophagy (CMA), a targeted, lysosome-dependent protein degradation pathway. Elevated LAMP2A levels, indicative of increased CMA activity, are observed in several malignancies, and CMA downre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f7c444a62405c2d5a9f291e5553505
http://europepmc.org/articles/PMC7527932