Zobrazeno 1 - 10
of 2 192
pro vyhledávání: '"Lysosomal enzymes"'
Autor:
Kurhaluk Natalia, Grudniewska Joanna, Pękala-Safińska Agnieszka, Pajdak-Czaus Joanna, Terech-Majewska Elżbieta, Platt-Samoraj Aleksandra, Tkaczenko Halina
Publikováno v:
Journal of Veterinary Research, Vol 68, Iss 3, Pp 325-336 (2024)
This study aimed to evaluate biomarkers of oxidative stress (2-thiobarbituric acid reactive substances, aldehyde and ketone derivatives of oxidatively modified proteins and total antioxidant capacity), the activity of antioxidant enzymes (superoxide
Externí odkaz:
https://doaj.org/article/b402b34759674097a581921ab4b70b67
Autor:
Tkaczenko Halina, Grudniewska Joanna, Pękala-Safińska Agnieszka, Terech-Majewska Elżbieta, Kurhaluk Natalia
Publikováno v:
Fisheries & Aquatic Life, Vol 31, Iss 3, Pp 133-146 (2023)
This study analyzed time-dependent effects of vaccination against Y. ruckeri on the oxidative mechanism underlying those effects by detecting relevant lipid peroxidation (2-thiobarbituric acid reactive substances, TBARS) and protein oxidation biomark
Externí odkaz:
https://doaj.org/article/4880df625be14989a7fd4c9e0153dfb1
Autor:
Eleonora Calzoni, Giada Cerrotti, Krizia Sagini, Federica Delo, Sandra Buratta, Roberto Maria Pellegrino, Husam B. R. Alabed, Federica Fratini, Carla Emiliani, Lorena Urbanelli
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 6, p 153 (2024)
Extracellular vesicles (EVs) can be isolated from biological fluids and cell culture medium. Their nanometric dimension, relative stability, and biocompatibility have raised considerable interest for their therapeutic use as delivery vehicles of macr
Externí odkaz:
https://doaj.org/article/4a60c4be7a2b40a4a1f15b07c4d54926
Autor:
Elize Dadaya, Benoit Bargui Koubala, Herve Ngatanko Abaissou, Stéphane Zingue, Dieudonne Ndjonka
Publikováno v:
Journal of HerbMed Pharmacology, Vol 10, Iss 4, Pp 383-393 (2021)
Introduction: Siphonochilus aethiopicus is a medicinal plant widely used in the treatment of many inflammatory conditions such as arthritis. The objective of this study was therefore to evaluate the antioxidant and anti-inflammatory properties of met
Externí odkaz:
https://doaj.org/article/fd7604aee05945f5b666e31a0ae9ed22
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2607 (2023)
Approximately 50% of all global blindness is caused by cataract in adults aged ≥50 years. The mechanisms of the disease are most arguably related to a redox imbalance and inflammation; therefore, the aim of the study was to evaluate the processes a
Externí odkaz:
https://doaj.org/article/e35aa5056e594be0aa37ca6fae4de0c3
Autor:
Ahmet Özer, Asli Aykac, Sermin Tetik, Omer Yiginer, Sule Cetinel, Naziye Ozkan, Mustafa Akkiprik, Zehra Kaya, Berrak Yegen, Mehmet Tezcan, Göksel Şener
Publikováno v:
İstanbul Kuzey Klinikleri, Vol 7, Iss 4, Pp 313-320 (2020)
OBJECTIVE: The present study aims to investigate the therapeutic effects of resveratrol (RES) on isoproterenol (ISO) induced myocardial injury rat model. METHODS: Catecholamine-induced heart damage was induced by ISO treatment for 30 days. The rats w
Externí odkaz:
https://doaj.org/article/e1292ff8b6ec41deb515efdfc35ceb55
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Autor:
Marialuisa Zedde, Rosario Pascarella, Francesco Cavallieri, Francesca Romana Pezzella, Sara Grisanti, Alessio Di Fonzo, Franco Valzania
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3132 (2022)
Anderson–Fabry disease (AFD) is an inherited lysosomal storage disorder characterized by a composite and multisystemic clinical phenotype and frequent involvement of the central nervous system (CNS). Research in this area has largely focused on the
Externí odkaz:
https://doaj.org/article/dad4f9439f7d4acb86a58eef7b7cbf75
Autor:
Marta Pawłowska, Celestyna Mila-Kierzenkowska, Tomasz Boraczyński, Michał Boraczyński, Karolina Szewczyk-Golec, Paweł Sutkowy, Roland Wesołowski, Marlena Budek, Alina Woźniak
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2445 (2022)
Physical activity has a positive effect on human health and well-being, but intense exercise can cause adverse changes in the organism, leading to the development of oxidative stress and inflammation. The aim of the study was to determine the effect
Externí odkaz:
https://doaj.org/article/114b455e7c5a4d37b1c5af0224d1f30f
Autor:
Tulasi Yadati, Tom Houben, Albert Bitorina, Yvonne Oligschlaeger, Marion J. Gijbels, Ronny Mohren, Dieter Lütjohann, Princy Khurana, Sandeep Goyal, Aditya Kulkarni, Jan Theys, Berta Cillero-Pastor, Ronit Shiri-Sverdlov
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background & AimsThe lysosomal enzyme, cathepsin D (CTSD) has been implicated in the pathogenesis of non-alcoholic steatohepatitis (NASH), a disease characterised by hepatic steatosis and inflammation. We have previously demonstrated that specific in
Externí odkaz:
https://doaj.org/article/cf1bfc25035041d38fc19938d67eb7f4