Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Lysosomal compartment"'
Autor:
Catarina Sabino, Michael Basic, Daniela Bender, Fabian Elgner, Kiyoshi Himmelsbach, Eberhard Hildt
Publikováno v:
Viruses, Vol 11, Iss 6, p 524 (2019)
Zika virus (ZIKV) is a highly transmissive virus that belongs to the Flaviviridae family, which comprises several other pathogens that threaten human health. This re-emerging virus gained attention during the outbreak in Brazil in 2016, where a consi
Externí odkaz:
https://doaj.org/article/28574d2f603b4ac6a484e1c30c2e19ae
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100916-(2021)
STAR Protocols
STAR Protocols
Summary The lysosomal compartment is a key hub for cell metabolism, and morphological alterations have been described in several pathological conditions. Here, we describe the use of amino acid analogs modified by the presence of a methyl ester group
Autor:
Ruth E. Carmichael, Laura DiGiovanni, Michael Schrader, Peter K. Kim, Rechal Kumar, Beatriz S.C. Silva
Publikováno v:
Biochim Biophys Acta Mol Cell Res
Biochimica et Biophysica Acta. Molecular Cell Research
Biochimica et Biophysica Acta. Molecular Cell Research
Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate and facilitate cellular functions. The formation of close contacts, termed “membrane contact sites” (MCSs), represents an intriguing strategy for organelle in
Publikováno v:
Sensors and Actuators B: Chemical. 260:460-464
Iron-rich lysosomal compartment causes a significant amount of cellular damage. A lysosome targetable, pH sensitive fluorescent chemosensor based on naphthalimide dye containing a catechol and morpholine moiety has been synthesized, which selectively
Autor:
Sebastian Müller, Ana M. Cuadro, Juan J. Vaquero, Raul Custodio, Emmanouil Zacharioudakis, Raphaël Rodriguez, Tatiana Cañeque
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:203-207
We have synthesized a collection of quinolizinium fluorescent dyes for the purpose of cell imaging. Preliminary biological studies in human U2OS osteosarcoma cancer cells have shown that different functional groups appended to the cationic quinolizin
Autor:
Kiyoshi Himmelsbach, Catarina Sabino, Fabian Elgner, Michael Basic, Daniela Bender, Eberhard Hildt
Publikováno v:
Viruses
Volume 11
Issue 6
Viruses, Vol 11, Iss 6, p 524 (2019)
Volume 11
Issue 6
Viruses, Vol 11, Iss 6, p 524 (2019)
Zika virus (ZIKV) is a highly transmissive virus that belongs to the Flaviviridae family, which comprises several other pathogens that threaten human health. This re-emerging virus gained attention during the outbreak in Brazil in 2016, where a consi
Autor:
Veronika Talianová, Vladimír Král, Pavel Martásek, Tomáš Bříza, Martin Havlík, Jarmila Králová, Bohumil Dolenský, Robert Kaplánek
Publikováno v:
Chemical communications (Cambridge, England). 55(18)
Four novel fluorescent cores bearing a transformable functional group based on a π-expanded naphthalimide including a fused pyranone or furan ring have been prepared. Fluorescent probes LysoSers 13–16 for lysosomal targeting have been tested. Co-l
Autor:
Wojciech, Trybus, Grzegorz, Król, Ewa, Trybus, Anna, Stachurska, Anna, Kopacz- Bednarska, Teodora, Król
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Aloe-emodin belongs to the group of anthraquinones having extremely high biological activity. The aim of this study was to evaluate the range of morphological and biochemical changes in HeLa cells treated with aloe-emodin, especially with
Publikováno v:
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 9(5)
Using nanoparticles to deliver drugs to cells has the potential to revolutionize the treatment of many diseases, including HIV, cancer, and diabetes. One of the major challenges facing this field is controlling where the drug is trafficked once the n
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