Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lysidine"'
Publikováno v:
Angewandte Chemie (International Ed. in English)
A major challenge in the field of RNA chemistry is the identification of selective and quantitative conversion reactions on RNA that can be used for tagging and any other RNA tool development. Here, we introduce metal‐free diazotransfer on native R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286e53c9990e1c7b7c8a191151f5592c
https://doi.org/10.1002/anie.202015034
https://doi.org/10.1002/anie.202015034
Autor:
Rebecca W. Alexander, Emil M. Nilsson
Publikováno v:
IUBMB Life
Nucleotides of transfer RNAs (tRNAs) are highly modified, particularly at the anticodon. Bacterial tRNAs that read A-ending codons are especially notable. The U34 nucleotide canonically present in these tRNAs is modified by a wide range of complex ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4023fecb54ee9caf7cc87fc54b476594
https://doi.org/10.1002/iub.2120
https://doi.org/10.1002/iub.2120
Publikováno v:
Biomolecules, Vol 7, Iss 2, p 35 (2017)
Transfer RNAs (tRNAs) are central players in translation, functioning as adapter molecules between the informational level of nucleic acids and the functional level of proteins. They show a highly conserved secondary and tertiary structure and the hi
Externí odkaz:
https://doaj.org/article/8e62ef8acb2f4d0fb971191e917239be
Autor:
Thomas Carell, Milda Nainyte
Publikováno v:
Helvetica Chimica Acta
Lysidine (k2C) is one of the most modified pyrimidine RNA bases. It is a cytidine nucleoside, in which the 2‐oxo functionality of the heterocycle is replaced by the ϵ‐amino group of the amino acid lysine. As such, lysidine is an amino acid‐con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0113d24252e5edf6139c2bf87cb8ef
Autor:
Mohammed Imam, Bandar Alrashid, Faizal Patel, Ahmed S. A. Dowah, Nathan Brown, Andrew Millard, Martha R. J. Clokie, Edouard E. Galyov
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 10 (2019)
Frontiers in Microbiology, Vol 10 (2019)
Phages are the most abundant biological entity on Earth. There are many variants in phage virion sizes, morphology, and genome sizes. Large virion sized phages, with genome sizes greater than 200 kbp have been identified and termed as Jumbo phages. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f340296e7f7b366abae19801531206b
http://europepmc.org/articles/PMC6892783
http://europepmc.org/articles/PMC6892783
Autor:
Joseph B. Sweeney, Scarlett M. Walton, Paul A. Bethel, Duncan M. Gill, Agata M. Ochocinska, Anthony E. J. Walsh
Publikováno v:
Organic letters. 21(7)
Anhydrouridines react with aliphatic amines to give N-alkyl isocytosines, but reported procedures often demand very long reaction times and can be low yielding, with narrow scope. A modified procedure for such reactions has been developed, using micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796d7330f5374b051a455454144271a7
https://pubmed.ncbi.nlm.nih.gov/30859822
https://pubmed.ncbi.nlm.nih.gov/30859822
Publikováno v:
Viruses
Volume 12
Issue 10
Viruses, Vol 12, Iss 1173, p 1173 (2020)
Volume 12
Issue 10
Viruses, Vol 12, Iss 1173, p 1173 (2020)
Viruses rely on their host&rsquo
s translation machinery for the synthesis of their own proteins. Problems belie viral translation when the host has a codon usage bias (CUB) that is different from an infecting virus due to differences in the GC
s translation machinery for the synthesis of their own proteins. Problems belie viral translation when the host has a codon usage bias (CUB) that is different from an infecting virus due to differences in the GC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bccd2f005dbd99ffed983198138953
https://doi.org/10.3390/v12101173
https://doi.org/10.3390/v12101173
Akademický článek
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Akademický článek
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Autor:
Kailas D. Sonawane, Susmit B. Sambhare
Publikováno v:
Integrative Biology. 7:1387-1395
Hypermodified nucleosides lysidine (L) and N(6)-threonylcarbamoyladenosine (t(6)A) influence codon-anticodon interactions during the protein biosynthesis process. Lysidine prevents the misrecognition of the AUG codon as isoleucine and that of AUA as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e79b8165a7e078c48a2145f91c6646f
https://doi.org/10.1039/c5ib00058k
https://doi.org/10.1039/c5ib00058k