Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

Autor: Olivier Hermine, Françoise Baleux, Bernard Lagane, Julie Harriague, Lysiane Klemm, Karl Balabanian, Françoise Bachelerie, Angélique Levoye, Fernando Arenzana-Seisdedos

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2008, 10, pp.1172-1183
Journal of Clinical Investigation, American Society for Clinical Investigation, 2008, 118 (3), pp.1074-84. ⟨10.1172/JCI33187⟩
Journal of Clinical Investigation, 2008, 118 (3), pp.1074-84. ⟨10.1172/JCI33187⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2008, 118 (3), pp.1074-84. 〈10.1172/JCI33187〉

International audience; Leukocytes from individuals with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a rare immunodeficiency, and bearing a wild-type CXCR4 ORF (WHIM(WT)) display impaired CXCR4 internalization and des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654ee31884a581ba7a718c265f938511
https://doi.org/10.1172/jci33187