Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lysandra Castro"'
Autor:
Zaniya A. Mark, Linda Yu, Lysandra Castro, Xiaohua Gao, Noelle R. Rodriguez, Deloris Sutton, Erica Scappini, Charles J. Tucker, Rob Wine, Yitang Yan, Evangeline Motley, Darlene Dixon
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4902 (2024)
High-risk human papillomavirus (HR-HPV; HPV-16) and cigarette smoking are associated with cervical cancer (CC); however, the underlying mechanism(s) remain unclear. Additionally, the carcinogenic components of tobacco have been found in the cervical
Externí odkaz:
https://doaj.org/article/f0e026734b7c443983bb02a139b3b7a6
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 917 (2022)
Cadmium (Cd) is one of the most prevalent environmental heavy metal contaminants and is considered an endocrine disruptor and carcinogen. In women with uterine fibroids, there is a correlation between blood Cd levels and fibroid tumor size. In this s
Externí odkaz:
https://doaj.org/article/86f436343bce470db556a61d865d8aa8
Publikováno v:
Nutrients, Vol 13, Iss 9, p 3048 (2021)
Advanced research in recent years has revealed the important role of nutrients in the protection of women’s health and in the prevention of women’s diseases. Genistein is a phytoestrogen that belongs to a class of compounds known as isoflavones,
Externí odkaz:
https://doaj.org/article/44e043ba289b4b7889570c7cc390d8a6
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186078 (2017)
ERα36 is a naturally occurring, membrane-associated, isoform of estrogen receptor α. The expression of ERα36 is due to alternative splicing and different promoter usage. ERα36 is a dominant-negative effector of ERα66-mediated transactivational a
Externí odkaz:
https://doaj.org/article/191cdfc97f864f2eb7f312a4e41fd0ad
Publikováno v:
Archives of Toxicology
Cadmium (Cd) is a toxic metal reported to act as an estrogen “mimic” in the rat uterus and in vitro. We have reported that Cd stimulates proliferation of estrogen-responsive human uterine leiomyoma (ht-UtLM; fibroid) cells through nongenomic sign
Autor:
Julie F. Foley, Min Shi, Jingli Liu, Lindsay A Santiago, Lysandra Castro, Michael Staup, Linda Yu, Trey Saddler, Linda S. Birnbaum, William Xue, Alanna Burwell, Darlene Dixon, Norris D Flagler
Publikováno v:
Toxicol Res Appl
Toxicology Research and Application, Vol 5 (2021)
Toxicology Research and Application, Vol 5 (2021)
Tetrabromobisphenol A (TBBPA) is a brominated flame retardant that induces endometrial adenocarcinoma and other uterine tumors in Wistar Han rats; however, early molecular events or biomarkers of TBBPA exposure remain unknown. We investigated the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d289bf433bda9dad3e101b0e75bcded
https://europepmc.org/articles/PMC8774279/
https://europepmc.org/articles/PMC8774279/
Autor:
Yitang Yan, Jingli Liu, Lysandra Castro, Carl D. Bortner, Maria I. Sifre, Darlene Dixon, Linda Yu
Publikováno v:
Arch Toxicol
Cadmium (Cd) is a ubiquitous environmental metal that is reported to be a “metalloestrogen.” Uterine leiomyomas (fibroids) are estrogen-responsive gynecologic neoplasms that can be the target of xenoestrogens. Previous epidemiology studies have s
Autor:
Xiaohua Gao, Darlene Dixon, Deloris Sutton, Linda Yu, Yitang Yan, Lysandra Castro, Alicia B. Moore, Connie A. Cummings
Publikováno v:
Genes, Chromosomes and Cancer. 55:397-406
Histone phosphorylation has a profound impact on epigenetic regulation of gene expression, chromosome condensation and segregation, and maintenance of genome integrity. Histone H3 Serine 10 is evolutionally conserved and heavily phosphorylated during
Autor:
Natasha P. Clayton, Jingli Liu, Lysandra Castro, Linda Yu, Darlene Dixon, Norris D. Flagler, Stephen S. Li, Pierre R. Bushel, Erica Scappini, Yitang Yan
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186078 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186078 (2017)
ERα36 is a naturally occurring, membrane-associated, isoform of estrogen receptor α. The expression of ERα36 is due to alternative splicing and different promoter usage. ERα36 is a dominant-negative effector of ERα66-mediated transactivational a