Comparison of cerebrospinal fluid biomarkers relevant to neurodegenerative diseases in healthy cynomolgus and rhesus macaque monkeys

Autor: Brittney Armitage-Brown, Andrew Winterborn, Susan E. Boehnke, De Felice Fg, Douglas J. Cook, Lyra e Silva Nm, Douglas P. Munoz, Robertson El

Structured AbstractINTRODUCTIONNon-human primates are important translational models of neurodegenerative disease. We characterized how species, sex, age, and site of sampling affected concentrations of key biomarkers of neurodegeneration.METHODSAmyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63be9cac5dec3af9cb96dabe599d8e52
https://doi.org/10.1101/2021.03.01.433384

Inflammation at the crossroads of COVID-19, cognitive deficits and depression.

Autor: Lyra E Silva NM; Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada; Department of Psychiatry, Queen's University, Kingston, ON, Canada. Electronic address: ndml@queensu.ca., Barros-Aragão FGQ; D'OR Institute for Research & Education, RJ, Brazil; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, RJ, Brazil. Electronic address: fernanda.aragao@idor.org., De Felice FG; Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada; Department of Psychiatry, Queen's University, Kingston, ON, Canada; D'OR Institute for Research & Education, RJ, Brazil; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, RJ, Brazil., Ferreira ST; D'OR Institute for Research & Education, RJ, Brazil; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, RJ, Brazil; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, RJ, Brazil.

Publikováno v: Neuropharmacology [Neuropharmacology] 2022 May 15; Vol. 209, pp. 109023. Date of Electronic Publication: 2022 Mar 04.

Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease.

Autor: Lyra E Silva NM; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada., Gonçalves RA; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada., Pascoal TA; Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, Douglas Mental Health University Institute, Montreal, Quebec, Canada., Lima-Filho RAS; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Resende EPF; Behavioral and Cognitive Neurology Research Group, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Vieira ELM; Centre of Addiction and Mental Health (CAMH), Toronto, ON, Canada., Teixeira AL; Neuropsychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Santa Casa BH Ensino e Pesquisa, Belo Horizonte, MG, Brazil., de Souza LC; Behavioral and Cognitive Neurology Research Group, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Peny JA; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Fortuna JTS; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Furigo IC; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Hashiguchi D; Department of Physiology, Federal University of São Paulo, São Paulo, SP, Brazil., Miya-Coreixas VS; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Clarke JR; School of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Abisambra JF; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease University of Florida, Gainesville, FL, USA., Longo BM; Department of Physiology, Federal University of São Paulo, São Paulo, SP, Brazil., Donato J Jr; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Fraser PE; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, Douglas Mental Health University Institute, Montreal, Quebec, Canada., Caramelli P; Behavioral and Cognitive Neurology Research Group, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Ferreira ST; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. ferreira@bioqmed.ufrj.br.; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. ferreira@bioqmed.ufrj.br., De Felice FG; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil. felice@bioqmed.ufrj.br.; Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada. felice@bioqmed.ufrj.br.; Department of Psychiatry, Queen's University, Kingston, ON, Canada. felice@bioqmed.ufrj.br.; Department of Biomedical and Molecuar Sciences, Queen's University, Kingston, ON, Canada. felice@bioqmed.ufrj.br.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2021 Apr 28; Vol. 11 (1), pp. 251. Date of Electronic Publication: 2021 Apr 28.

Linking the reversal of gestational insulin resistance to postpartum depression.

Autor: Abeysekera, Minoli Vinoda¹ (AUTHOR), Ni, Duan^1,2 (AUTHOR), Gilbert, Leah³ (AUTHOR), Hibbert, Emily^1,2,3 (AUTHOR), Nanan, Ralph^1,2,3 (AUTHOR) ralph.nanan@sydney.edu.au

Publikováno v: BMC Medicine. 10/8/2024, Vol. 22 Issue 1, p1-6. 6p.

Inhibitory activities of Aruncus dioicus alkaloidal glycosides against protein tyrosine phosphatase 1B and α-glucosidase: A methodical theory-experiment investigation.

Autor: Phi-Hung Nguyen^1,2,3 nguyenphihung@inpc.vast.vn, Bui, Thanh Q.⁴, Thi-Tuyen Tran¹, Thi-Thuc Bui^1,2, Thi-Thuy Do³, Dao-Cuong To⁵, Manh Hung Tran⁶, Phan Tu Quy⁷, Nguyen Quang Co⁸, Nguyen Vinh Phu⁹, Nguyen Thi Ai Nhung⁴ ntanhung@hueuni.edu.vn

Publikováno v: Natural Product Communications. Aug2024, Vol. 19 Issue 8, p1-17. 17p.