Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lyra B. Olson"'
Autor:
Lingye Chen, Lyra B. Olson, Ibtehaj A. Naqvi, Bruce A. Sullenger, Loretta G. Que, Thomas N. Denny, Bryan D. Kraft
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Severe COVID-19 carries a high morbidity and mortality. Previous studies have shown an association between COVID-19 severity and SARS-CoV-2 viral load (VL). We sought to measure VL in multiple compartments (urine, plasma, lower re
Externí odkaz:
https://doaj.org/article/8a7d334a2f224a689d615104e20f3409
Autor:
Aditya A. Mohan, BSc, Lyra B. Olson, PhD, Ibtehaj A. Naqvi, MD, PhD, Sarah A. Morrison, PhD, Bryan D. Kraft, MD, Lingye Chen, MD, Loretta G. Que, MD, Qing Ma, PhD, Christina E. Barkauskas, MD, Allan Kirk, MD, PhD, Smita K. Nair, PhD, Bruce A. Sullenger, PhD, George Kasotakis, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 4, Iss 12, p e0799 (2022)
OBJECTIVES:. The COVID-19 pandemic has claimed over eight hundred thousand lives in the United States alone, with older individuals and those with comorbidities being at higher risk of severe disease and death. Although severe acute respiratory syndr
Externí odkaz:
https://doaj.org/article/dc9548d080d84b5c94caf1198546cf58
Autor:
Lyra B. Olson, Nicole I. Hunter, Rachel E. Rempel, Haixiang Yu, Diane M. Spencer, Cynthia Z. Sullenger, William S. Greene, Anastasia K. Varanko, Seyed A. Eghtesadi, Ashutosh Chilkoti, David S. Pisetsky, Jeffrey I. Everitt, Bruce A. Sullenger
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105542- (2022)
Summary: Nucleic acid-binding polymers can have anti-inflammatory properties and beneficial effects in animal models of infection, trauma, cancer, and autoimmunity. PAMAM G3, a polyamidoamine dendrimer, is fully cationic bearing 32 protonable surface
Externí odkaz:
https://doaj.org/article/c47c0949e0684823b161722dd21838e4
Publikováno v:
Case Reports in Infectious Diseases, Vol 2019 (2019)
We present the case of a 92-year-old man with septic arthritis of a prosthetic hip joint due to Streptococcus salivarius one week following a high-risk dental procedure despite preprocedure amoxicillin. S. salivarius is a commensal bacterium of the h
Externí odkaz:
https://doaj.org/article/b078fb368aec4acda05adeb132558f5b
Autor:
Kristin M. Corey, Lyra B. Olson, Ibtehaj A. Naqvi, Sarah A. Morrison, Connor Davis, Shahid M. Nimjee, Loretta G. Que, Robin E. Bachelder, Bryan D. Kraft, Lingye Chen, Smita K. Nair, Jerrold H. Levy, Bruce A. Sullenger
Publikováno v:
Anesthesiology
Background COVID-19 causes hypercoagulability, but the association between coagulopathy and hypoxemia in critically ill patients has not been thoroughly explored. This study hypothesized that severity of coagulopathy would be associated with acute re
Autor:
Charlene V. Chabata, James W. Frederiksen, Lyra B. Olson, Ibtehaj A. Naqvi, Sharon E. Hall, Ruwan Gunaratne, Bryan D. Kraft, Loretta G. Que, Lingye Chen, Bruce A. Sullenger
Publikováno v:
Nucleic Acid Ther
Known limitations of unfractionated heparin (UFH) have encouraged the evaluation of anticoagulant aptamers as alternatives to UFH in highly procoagulant settings such as cardiopulmonary bypass (CPB). Despite progress, these efforts have not been tota
Publikováno v:
Transl Res
Systemic lupus erythematosus (SLE) is a chronic and often progressive autoimmune disorder marked clinically by a variable constellation of symptoms including fatigue, rash, joint pains, and kidney damage. The lungs, heart, gastrointestinal system, an
Autor:
Lingye Chen, Lyra B. Olson, Ibtehaj A. Naqvi, Bruce A. Sullenger, Smita K Nair, Loretta G. Que, Thomas N. Denny, Bryan D. Kraft
COVID-19 can cause acute respiratory distress syndrome (ARDS) associated with high morbidity and mortality. Previous studies have shown an association between plasma viral load (VL) of severe acute respiratory distress (SARS-Cov2) and disease severit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6080b56c38f2a4023b4f60f4b786a2a8
https://doi.org/10.21203/rs.3.rs-2362894/v1
https://doi.org/10.21203/rs.3.rs-2362894/v1
Autor:
Jerrold H. Levy, Jean M. Connors, Kamrouz Ghadimi, Kristen M Corey, Lyra B. Olson, Toshiaki Iba
Publikováno v:
International Journal of Laboratory Hematology
Vascular endothelial injury is a hallmark of acute infection at both the microvascular and macrovascular levels. The hallmark of SARS‐CoV‐2 infection is the current COVID‐19 clinical sequelae of the pathophysiologic responses of hypercoagulabil
Autor:
Imran Ozer, George A. Pitoc, Juliana M. Layzer, Angelo Moreno, Lyra B. Olson, Kyle D. Layzer, Angus M. Hucknall, Bruce A. Sullenger, Ashutosh Chilkoti
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(10)
Ribonucleic acid (RNA) therapeutics are an emerging class of drugs. RNA aptamers are of significant therapeutic and clinical interest because their activity can be easily reversed in vivo-a useful feature that is difficult to achieve using other ther