Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lyong Heo"'
Autor:
Dario Ferrari, Arunima Sengupta, Lyong Heo, Laszlo Pethö, Johann Michler, Thomas Geiser, Vinicio A. de Jesus Perez, Wolfgang M. Kuebler, Soheila Zeinali, Olivier T. Guenat
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106198- (2023)
Summary: The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)). Upon alteration of these biomechanical cues, endothelial
Externí odkaz:
https://doaj.org/article/3c2cdd3bf6914d0980ff44688f865d7c
Autor:
Maggie H Chasse, Benjamin K Johnson, Elissa A Boguslawski, Katie M Sorensen, Jessica E Rosien, Min H Kang, C Patrick Reynolds, Lyong Heo, Zachary B Madaj, Ian Beddows, Gabrielle E Foxa, Susan M Kitchen‐Goosen, Bart O Williams, Timothy J Triche, Patrick J Grohar
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-21 (2020)
Abstract Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic opti
Externí odkaz:
https://doaj.org/article/18bf94a3ea2d4e32b5861a62e60c62a8
Publikováno v:
International Journal of Genomics, Vol 2015 (2015)
Exome-based genotyping arrays are cost-effective and have recently been used as alternative platforms to whole-exome sequencing. However, the automated clustering algorithm in an exome array has a genotype calling problem in accuracy for identifying
Externí odkaz:
https://doaj.org/article/332eff33b066454282dca70a714ebc7b
Autor:
Katie M. Sorensen, Min H. Kang, Bart O. Williams, Lyong Heo, Patrick J. Grohar, Timothy J. Triche, Jessica E Rosien, C. Patrick Reynolds, Maggie H. Chasse, Zachary Madaj, Gabrielle E. Foxa, Benjamin K. Johnson, Ian Beddows, Elissa Boguslawski, Susan M. Kitchen-Goosen
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic options for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce177656448726f6f48983b706f49feb
https://pubmed.ncbi.nlm.nih.gov/33332735
https://pubmed.ncbi.nlm.nih.gov/33332735
Autor:
Lyong Heo, Chan Soo Shin, Kwang Joong Kim, Mi Yeong Hwang, Bong Jo Kim, Hyung Jin Choi, Yeon Jung Kim, Young Jin Kim
Publikováno v:
Genes & Genomics. 37:339-346
A 4 bp deletion in GNAS has known to be the causal mutation for pseudohypoparathyroidism. In this study, we performed sanger sequencing on exons of GNAS and identified the 4 bp causal deletion in Korean family with pseudohypoparathyroidism. Despite t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a692eeaeda9c68707063598d84f24ee
https://doi.org/10.1007/s13258-014-0261-2
https://doi.org/10.1007/s13258-014-0261-2
Autor:
Bok-Ghee Han, Bong-Jo Kim, Hye-Ja Lee, Tae Joon Park, Lyong Heo, Han Byul Jang, Kyung Hee Park, Ju Young Lee, Min Jin Go, Jihyun Song, Jae Heon Kang, Joo-Yeon Hwang
Publikováno v:
Genomics. 104:594-598
• A genome wide association study identifies a LEPR gene as a novel predisposing factor for childhood fasting plasma glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986b135fa897cb2ea0a87f63cf5c3ab3
https://doi.org/10.1016/j.ygeno.2014.09.001
https://doi.org/10.1016/j.ygeno.2014.09.001
Autor:
Ji-Young Lee, Bok-Soo Lee, Dong-Jik Shin, Kyung Woo Park, Young-Ah Shin, Kwang Joong Kim, Lyong Heo, Ji Young Lee, Yun Kyoung Kim, Young Jin Kim, Chang Bum Hong, Sang-Hak Lee, Dankyu Yoon, Hyo Jung Ku, Il-Young Oh, Bong-Jo Kim, Juyoung Lee, Seon-Joo Park, Jimin Kim, Hye-kyung Kawk, Jong-Eun Lee, Hye-kyung Park, Jae-Eun Lee, Hye-young Nam, Hyun-young Park, Chol Shin, Mitsuhiro Yokota, Hiroyuki Asano, Masahiro Nakatochi, Tatsuaki Matsubara, Hidetoshi Kitajima, Ken Yamamoto, Hyung-Lae Kim, Bok-Ghee Han, Myeong-Chan Cho, Yangsoo Jang, Hyo-Soo Kim, Jeong Euy Park, Jong-Young Lee
Publikováno v:
Journal of Human Genetics. 58:120-126
Although over 30 common genetic susceptibility loci have been identified to be independently associated with coronary artery disease (CAD) risk through genome-wide association studies (GWAS), genetic risk variants reported to date explain only a smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669a254f07c8933c7be5147460093525
https://doi.org/10.1038/jhg.2012.124
https://doi.org/10.1038/jhg.2012.124
Autor:
Benjamin K. Johnson, Yizhou Peter Huang, Lyong Heo, Hamid Bolouri, Rhonda E. Ries, Timothy J. Triche, Jason E. Farrar, Soheil Meshinchi
Publikováno v:
Blood. 132:2609-2609
Relapsing and refractory acute myeloid leukemia (AML) is responsible for dismal outcomes in both pediatric and adult patients. However, we (Bolouri, Farrar, Triche, Reis et al, Nature Medicine 2018) and others have demonstrated that the mutational bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3d3ce091ca4dcfdaf7a51dfcbe88f9
https://doi.org/10.1182/blood-2018-99-119323
https://doi.org/10.1182/blood-2018-99-119323
Publikováno v:
International Journal of Genomics, Vol 2015 (2015)
International Journal of Genomics
International Journal of Genomics
Exome-based genotyping arrays are cost-effective and have recently been used as alternative platforms to whole-exome sequencing. However, the automated clustering algorithm in an exome array has a genotype calling problem in accuracy for identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bdddcb85d1e64ce3357b0904027390
Autor:
Bok-Ghee Han, Il Ju Choi, Jong-Young Lee, Min Jin Go, Duk-Hwan Kim, Young-Woo Kim, Ju Young Lee, Bong-Jo Kim, Yeon-Su Lee, Sung Kim, Yongick Ji, Joobae Park, Jae Hyung Noh, Young-Jin Kim, Sook-Young Kim, Keun Won Ryu, Joo-Yeon Hwang, Tae Sung Sohn, Lyong Heo
Publikováno v:
Journal of Human Genetics. 58:233-235
Gastric cancer (GC) is the most common malignancy. The incidence rates remain remarkably high in East Asians. Although genome-wide association studies in the Han Chinese and Japanese populations have so far yielded susceptibility loci for GC, these f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ff15aec4737589c64b16869aa57f0e
https://doi.org/10.1038/jhg.2012.158
https://doi.org/10.1038/jhg.2012.158