Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lynsey M. Fettig"'
Autor:
Ashley V. Ward, Shawna B. Matthews, Lynsey M. Fettig, Duncan Riley, Jessica Finlay-Schultz, Peter Kabos, Matthew Jackman, Paul S. MacLean, Carol A. Sartorius
Metabolic reprogramming remains largely understudied in relation to hormones in estrogen receptor (ER) and progesterone receptor (PR) positive breast cancer. In this study, we investigated how estrogens, progestins, or the combination, impact metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7639ecc435ccfd3320f0ce7d49209482
https://doi.org/10.21203/rs.2.23619/v3
https://doi.org/10.21203/rs.2.23619/v3
Autor:
Ashley V. Ward, Shawna B. Matthews, Lynsey M. Fettig, Duncan Riley, Jessica Finlay-Schultz, Kiran V. Paul, Matthew Jackman, Peter Kabos, Paul S. MacLean, Carol A. Sartorius
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1776
Metabolic reprogramming remains largely understudied in relation to hormones in estrogen receptor (ER) and progesterone receptor (PR) positive breast cancer. In this study, we investigated how estrogens, progestins, or the combination, impact metabol
Autor:
Sylaja Murikipudi, Andrea R Delpero, Thomas M. Lancaster, Xihong Zhang, Kelly LaPara, Lynsey M. Fettig, Douglas Yee, Todd C. Zion
Publikováno v:
Cancer Research. 80:P1-21
A link between obesity, metabolic dysfunction, and an increased risk in cancer mortality has been well established in several cancer types including, breast, colon, pancreatic, and prostate cancers. A likely mechanism driving this elevated risk is th
Autor:
Kiran V. Paul, Olivia McGinn, Ashley V. Ward, Lynsey M. Fettig, Peter Kabos, Jessica Finlay-Schultz, Carol A. Sartorius, Duncan Riley, Joshua J. Ivie
Publikováno v:
Oncogene
Estrogen receptor (ER) positive breast cancers often contain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5). CK5+ cells are enriched in cancer stem cell (CSC) properties, can be induced by progestins, and p
Autor:
Jingran Cao, Lynsey M. Fettig, Kelly LaPara, Xihong Zhang, Sylaja Murikipudi, Andrea R. Delpero, Thomas M. Lancaster, Todd C. Zion, Douglas Yee
Publikováno v:
Cancer Research. 82:P4-02
Obesity and metabolic dysfunction are on the rise in the United States. Hyperinsulinemia, frequently seen in these conditions, correlates with an increased risk of development and mortality from estrogen receptor (ER) positive breast cancer. Expressi
Autor:
Matthew Jackman, Paul S. MacLean, Peter Kabos, Ashley V. Ward, Shawna B. Matthews, Lynsey M. Fettig, Carol A. Sartorius, Jessica Finlay-Schultz
Progesterone receptors (PR) profoundly influence breast cancer biology by modifying estrogen receptor (ER) gene regulation, and, under some contexts, increasing populations of cancer stem cells. Abnormal metabolism is a cancer hallmark that has large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198ecd9cca5f696de14ce582783040f4
https://doi.org/10.21203/rs.2.23619/v2
https://doi.org/10.21203/rs.2.23619/v2
Autor:
Matthew Jackman, Paul S. MacLean, Ashley V. Ward, Peter Kabos, Lynsey M. Fettig, Carol A. Sartorius, Shawna B. Matthews, Jessica Finlay-Schultz
Background Progestins generally suppress the growth of estrogen receptor (ER) and progesterone receptor (PR) positive breast cancers and are occasionally used as treatments. However, progestins also increase populations of therapy-resistant cancer st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::530ef48ff22a3f55f90455206ccf0cf5
https://doi.org/10.21203/rs.2.23619/v1
https://doi.org/10.21203/rs.2.23619/v1
Autor:
Lynsey M. Fettig, Douglas Yee
Publikováno v:
Adv Cancer Res
The insulin and insulin-like growth factor (IGF) family of proteins are part of a complex network that regulates cell proliferation and survival. While this system is undoubtedly important in prenatal development and postnatal cell growth, members of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c8b10b5b00d90800160175fd77a672
https://doi.org/10.1016/bs.acr.2020.04.005
https://doi.org/10.1016/bs.acr.2020.04.005
Autor:
Daniel V. LaBarbera, Carol A. Sartorius, Lynsey M. Fettig, S K Nordeen, Jessica Finlay-Schultz, Olivia McGinn
Publikováno v:
Oncogene. 36:6074-6084
Half of estrogen receptor-positive breast cancers contain a subpopulation of cytokeratin 5 (CK5)-expressing cells that are therapy resistant and exhibit increased cancer stem cell (CSC) properties. We and others have demonstrated that progesterone (P
Autor:
Lisa R. Young, Mark W. Geraci, Naoko Hara, David S. Conklin, Amber Cornelius, Tzu L. Phang, Elizabeth A. Mickler, Robert S Stearman, Lynsey M. Fettig, Xiao Lu
Publikováno v:
Am J Respir Crit Care Med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5332a37762c7c05d89ecee2d2e75f19a
https://europepmc.org/articles/PMC6835081/
https://europepmc.org/articles/PMC6835081/