Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Lynsey M Cree"'
Autor:
Donna L Nile, Audrey E Brown, Meutia A Kumaheri, Helen R Blair, Alison Heggie, Satomi Miwa, Lynsey M Cree, Brendan Payne, Patrick F Chinnery, Louise Brown, David A Gunn, Mark Walker
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115433 (2014)
Type 2 diabetes is characterised by an age-related decline in insulin secretion. We previously identified a 50% age-related decline in mitochondrial DNA (mtDNA) copy number in isolated human islets. The purpose of this study was to mimic this degree
Externí odkaz:
https://doaj.org/article/a5d3b7f6a6c14dbcae578e14fc6d4ae3
Publikováno v:
Molecular Human Reproduction.
Currently, our understanding of hormonal regulation within the female reproductive system is largely based on our knowledge of estrogen and progesterone signalling. However, while the important functions of androgens in male physiology are well known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312a42fbba77c36dd3ff5e3a3946223f
https://doi.org/10.1093/molehr/gaad017
https://doi.org/10.1093/molehr/gaad017
Autor:
Lynsey M. Cree
Publikováno v:
Human Reproduction. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe0c7617b2f477a4731cba7b2f50234
https://doi.org/10.1093/humrep/deab126.037
https://doi.org/10.1093/humrep/deab126.037
Publikováno v:
Systems Biology in Reproductive Medicine. 65:451-457
Sperm DNA integrity is important for fertility, however the incidence of high levels of DNA fragmentation (DNA fragmentation index (DFI)30%) is not well described. In 2011, our clinics implemented guidelines for sperm DNA fragmentation (SDF) testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651167136b6dc0fe3e416ff8a8e8a13b
https://doi.org/10.1080/19396368.2019.1668077
https://doi.org/10.1080/19396368.2019.1668077
Publikováno v:
J Assist Reprod Genet
RESEARCH QUESTION: To investigate whether patient factors influence the decision to freeze a blastocyst with low implantation potential. DESIGN: This experimental study assessed 170 practicing embryologists from a variety of countries who were recrui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f5198ed3c2a1222ed2f1e6a56a1750
https://europepmc.org/articles/PMC7468049/
https://europepmc.org/articles/PMC7468049/
Publikováno v:
Human Reproduction. 33:991-997
Extended culture to the blastocyst stage is widely practised, improving embryo selection and promoting single embryo transfer. Selection of useable blastocysts typically occurs on Days 5 and 6 of embryo culture. Embryos not suitable for transfer, bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e485c0279493733fdb45c5124167f0
https://doi.org/10.1093/humrep/dey091
https://doi.org/10.1093/humrep/dey091
Autor:
Lynsey M. Cree, Qi Chen, Caroline L. Johansson, Peter Stone, Lawrence W. Chamley, Mancy Tong, Fengyi Xiao, Joanna L. James
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
The pathogenesis of preeclampsia remains unclear but placental factors are known to play a crucial role causing maternal endothelial cell dysfunction. One potential factor is placental micro-and nano-vesicles. Antiphospholipid antibodies (aPL) increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58e728dd8e6e5290c1b2375334faf97
http://link.springer.com/article/10.1038/s41598-017-16448-5
http://link.springer.com/article/10.1038/s41598-017-16448-5
Autor:
Cindy Farquhar, Lynsey M. Cree
Publikováno v:
Fertility and sterility. 113(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b30abc3f7c5de4360dba5aa2ee97e05
https://pubmed.ncbi.nlm.nih.gov/32106973
https://pubmed.ncbi.nlm.nih.gov/32106973
Publikováno v:
Human Reproduction. 31:1653-1661
The ability to screen embryos for aneuploidy or inherited disorders in a minimally invasive manner may represent a major advancement for the future of embryo viability assessment. Recent studies have demonstrated that both blastocoele fluid and embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02721daf4c56ee91238a8fd5ec7217b7
https://doi.org/10.1093/humrep/dew132
https://doi.org/10.1093/humrep/dew132
Autor:
Lynsey M. Cree, Ian A. Trounce, David R. Powell, Kanokwan Srirattana, Fernando J. Rossello, Gael Cagnone, Te-Sha Tsai, Gary A. Rohrer, Justin C. St. John
Publikováno v:
Genetics. 202:931-944
The maternally inherited mitochondrial genome (mtDNA) is present in multimeric form within cells and harbors sequence variants (heteroplasmy). While a single mtDNA variant at high load can cause disease, naturally occurring variants likely persist at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fa7b34b79fac07f6400cbb04bb075d
https://doi.org/10.1534/genetics.115.181321
https://doi.org/10.1534/genetics.115.181321