Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lynnelle Thorpe"'
Autor:
Jodie M. Fleming, Charles M. Perou, Melissa A. Troester, David McDonald, Jyla Hicks, Lynnelle Thorpe, Michael Bereman, Dereje D. Jima, Katerina D. Fagan-Solis, Katherine A. Hoadley, Denise K. Reaves
Supplementary Table 1. Mutations in LSR from Human Cancer Samples. Supplementary Table 2. Potential post-translational modification sites of LSR transcript variants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba4ab2e5d01dfc8e5347f106d3e0252
https://doi.org/10.1158/1541-7786.22511797.v1
https://doi.org/10.1158/1541-7786.22511797.v1
Autor:
Jodie M. Fleming, Charles M. Perou, Melissa A. Troester, David McDonald, Jyla Hicks, Lynnelle Thorpe, Michael Bereman, Dereje D. Jima, Katerina D. Fagan-Solis, Katherine A. Hoadley, Denise K. Reaves
Lipolysis-stimulated lipoprotein receptor (LSR) has been found in the plasma membrane and is believed to function in lipoprotein endocytosis and tight junctions. Given the impact of cellular metabolism and junction signaling pathways on tumor phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d7e8d3ce895b29e51f9dc2fa25af6f
https://doi.org/10.1158/1541-7786.c.6540046.v1
https://doi.org/10.1158/1541-7786.c.6540046.v1
Autor:
Jodie M. Fleming, Charles M. Perou, Melissa A. Troester, David McDonald, Jyla Hicks, Lynnelle Thorpe, Michael Bereman, Dereje D. Jima, Katerina D. Fagan-Solis, Katherine A. Hoadley, Denise K. Reaves
S1. QPCR analysis of luminal progenitor and cancer stem cell genes. Primers were designed against the indicated genes. S2. Representative Z-stack projections of MCF7 breast cancer and MCF10AI breast epithelial cells generated from deconvolved slices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafe6fdba6802f38d63e2374029ad22b
https://doi.org/10.1158/1541-7786.22511803.v1
https://doi.org/10.1158/1541-7786.22511803.v1
Autor:
Jodie M. Fleming, Charles M. Perou, Melissa A. Troester, David McDonald, Jyla Hicks, Lynnelle Thorpe, Michael Bereman, Dereje D. Jima, Katerina D. Fagan-Solis, Katherine A. Hoadley, Denise K. Reaves
Supplementary Information including supplementary figure legends and supplementary table titles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764e54e1792aedbfac06b8fde155eb7e
https://doi.org/10.1158/1541-7786.22511800
https://doi.org/10.1158/1541-7786.22511800
Autor:
Gary E. Gallick, Christopher J. Logothetis, Sue-Hwa Lin, Mian Alauddin, Yiping Shao, Bogdan A. Czerniak, Menashe Bar Eli, Sankar N. Maity, Lynnelle Thorpe, Sanchaika Gaur, Anh G. Hoang, Ana Aparicio, Yu-Chen Lee, Jian H. Song, Eleni Efstathiou, Nila U. Parikh, Paul G. Corn, Andreas Varkaris
Supplemental Figure 1 (fig. S1). Representative whole body NaF-18 PET scan images after 44 days of (A) vehicle-treated and (B) cabozantinib-treated animals. Supplemental Figure 2 (fig. S2). Effect of cabozantinib on PDX tumor growth, animal weight, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1771a12684127acc4701f3e4133b4f8d
https://doi.org/10.1158/1078-0432.22461362
https://doi.org/10.1158/1078-0432.22461362
Autor:
Gary E. Gallick, Christopher J. Logothetis, Sue-Hwa Lin, Mian Alauddin, Yiping Shao, Bogdan A. Czerniak, Menashe Bar Eli, Sankar N. Maity, Lynnelle Thorpe, Sanchaika Gaur, Anh G. Hoang, Ana Aparicio, Yu-Chen Lee, Jian H. Song, Eleni Efstathiou, Nila U. Parikh, Paul G. Corn, Andreas Varkaris
Purpose: We performed parallel investigations in cabozantinib-treated patients in a phase II trial and simultaneously in patient-derived xenograft (PDX) models to better understand the roles of MET and VEGFR2 as targets for prostate cancer therapy.Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f627afa09d75e41a7e6ac87ed12b9c4
https://doi.org/10.1158/1078-0432.c.6524774
https://doi.org/10.1158/1078-0432.c.6524774
Autor:
Gary E. Gallick, Christopher J. Logothetis, Sue-Hwa Lin, Mian Alauddin, Yiping Shao, Bogdan A. Czerniak, Menashe Bar Eli, Sankar N. Maity, Lynnelle Thorpe, Sanchaika Gaur, Anh G. Hoang, Ana Aparicio, Yu-Chen Lee, Jian H. Song, Eleni Efstathiou, Nila U. Parikh, Paul G. Corn, Andreas Varkaris
supplementary materials and methods, supplementary tables and supplementary figure legends Supplemental Table 1: Patient Characteristics. Supplemental Table 2: Targeting sequences for c-met. Supplemental Table 3: Antibodies and Sources. Supplemental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22eaeb0f86f14ce9b6ab154dcb5972a4
https://doi.org/10.1158/1078-0432.22461359
https://doi.org/10.1158/1078-0432.22461359
Autor:
Denise K. Reaves, Jyla Hicks, Lynnelle Thorpe, David A. McDonald, Michael S. Bereman, Katherine A. Hoadley, Jodie M. Fleming, Katerina D. Fagan-Solis, Dereje D. Jima, Melissa A. Troester, Charles M. Perou
Publikováno v:
Molecular cancer research : MCR. 15(2)
Lipolysis-stimulated lipoprotein receptor (LSR) has been found in the plasma membrane and is believed to function in lipoprotein endocytosis and tight junctions. Given the impact of cellular metabolism and junction signaling pathways on tumor phenoty
Autor:
Lynnelle Thorpe, Nicole L. Pinaire, Mark J. Routbort, Nikhil S. Chari, L. Jeffrey Medeiros, Timothy J. McDonnell
Publikováno v:
Apoptosis : an international journal on programmed cell death. 14(4)
The molecular subversion of cell death is acknowledged as a principal contributor to the development and progression of cancer. The p53 tumor suppressor protein is among the most commonly altered proteins in human cancer. The p53 protein mediates cri
Publikováno v:
Cancer Research. 72:A65-A65
Background: Prostate cancer (PCa) is the second leading cause of cancer deaths. Deaths invariably result from metastasis, most commonly to the bone. Tumor-microenvironment interactions of metastatic PCa in the bone are critical for growth at the meta