Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lynnell Zempoaltecatl"'
Autor:
Joshua W. Parks, Ricardo Carrion, Jean P. Patterson, Holger Schmidt, Hong Cai, Lynnell Zempoaltecatl, Aaron R. Hawkins
Publikováno v:
CLEO: 2014.
Clinical Ebola RNAs are detected with virus concentration down to 6.25 t10^4pfu/ml on an optofluidic chip. Longer complementary pull-down DNA sequences provide better isolation and higher signals.
Publikováno v:
CLEO: 2014.
Lambda DNA (λ-DNA) molecules were labeled with SYBR Gold nucleic acid stain using a PDMS-based programmable microfluidic chip (Automaton). Single DNA molecules were detected in a vertically integrated liquid-core waveguide chip.
Publikováno v:
SPIE Proceedings.
Using silicon based microfabrication and materials we have developed a photonic platform capable of single bioparticle analysis. This platform combines liquid and hollow core waveguides on the micron-scale (5 μm x 12 μm) to isolate femtoliter sized
Publikováno v:
SPIE Newsroom.
Autor:
Lynnell Zempoaltecatl, Joseph W. Parks, Steven P. Miller, Holger Schmidt, Charles Y. Chiu, Aaron R. Hawkins, Philip Measor, Samia N. Naccache
Publikováno v:
CLEO: 2013.
We demonstrate strain-specific detection of single virus nucleic acid molecules from clinical influenza samples using an optofluidic chip. We observe a limit of detection of 104 virus copies/mL and 10 orders of magnitude dynamic range.
Autor:
Damla Ozcelik, Lynnell Zempoaltecatl, Joseph W. Parks, Holger Schmidt, Jennifer A. Black, Y. Lim, Kaelyn D. Leake, Aaron R. Hawkins
Publikováno v:
CLEO: 2013.
Fluorescence detection with enhanced sensitivity is demonstrated on liquid-core waveguide chips using Y-splitters to create multiple excitation spots and applying a single signal processing step. The signal-to-noise ratio is enhanced by 200 times.
Autor:
Samia N. Naccache, Aaron R. Hawkins, Shuo Liu, Hong Cai, Charles Y. Chiu, Holger Schmidt, Damla Ozcelik, Philip Measor, Lynnell Zempoaltecatl, Joshua W. Parks
Publikováno v:
Scopus-Elsevier
Recent progress in developing optofluidic waveguide devices for single particle analysis with emphasis on biomedical applications will be discussed.
Autor:
Aaron R. Hawkins, Kaelyn D. Leake, Lynnell Zempoaltecatl, Joshua W. Parks, Hong Cai, Holger Schmidt, T. D. Yuzvinsky
Publikováno v:
Lab on a Chip. 13:4118
Complete integration of microfluidic and optical functions in a single lab-on-chip device is one goal of optofluidics. Here, we demonstrate the hybrid integration of a PDMS-based fluid handling layer with a silicon-based optical detection layer in a
Autor:
Hong Cai, Joseph W. Parks, Aaron R. Hawkins, Lynnell Zempoaltecatl, Richard A. Mathies, Damla Ozcelik, Jungkyu Kim, Holger Schmidt
Publikováno v:
Scopus-Elsevier
Integrated fluidic control and optical detection are presented through the synthesis of microfluidic automata and optofluidic waveguides. Analyte mixing and fluid velocity are controlled on Automaton while optical detection is achieved via liquid-cor
Externí odkaz:
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