Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lynnea R. Waters"'
Publikováno v:
iScience, Vol 5, Iss , Pp 99-109 (2018)
Summary: B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response.
Externí odkaz:
https://doaj.org/article/558153aa07ac42aba37a7a0d62887f41
Autor:
Thomas G. Graeber, Diane N. H. Kim, Jason S. Hong, Fasih M. Ahsan, Michael A. Teitell, Johanna ten Hoeve, Daniel Braas, Lynnea R. Waters, Aspram Minasyan, Thomas A. Zangle
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific reports, vol 9, iss 1
Scientific Reports
Scientific reports, vol 9, iss 1
Scientific Reports
Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic processes. Recently, we showed that Lkb1, an understudied kinase in B lymphocytes and a major u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c979b7020c104fa3f91326e4c6a296c7
http://link.springer.com/article/10.1038/s41598-019-43985-y
http://link.springer.com/article/10.1038/s41598-019-43985-y
Publikováno v:
iScience, Vol 5, Iss, Pp 99-109 (2018)
Summary: B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88541e8a98824399cb6484b6272036e
http://www.sciencedirect.com/science/article/pii/S2589004218300932
http://www.sciencedirect.com/science/article/pii/S2589004218300932
Publikováno v:
Gene Reports. 4:272-279
Yme1-like 1 (yme1L1) is a mouse ortholog of Saccharomyces cerevisiae yme1p, a protein that degrades unfolded or misfolded mitochondrial gene products and is essential for protecting mitochondrial morphology and mitochondrial genome integrity. Other y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295946880c759701df6cec7ba110715e
https://doi.org/10.1016/j.genrep.2016.07.012
https://doi.org/10.1016/j.genrep.2016.07.012
Publikováno v:
Cancer Immunology Research. 6:B46-B46
Defense from infection or cancer is provided by coordinated actions of the innate and adaptive immune system, including B lymphocytes that generate antibodies (Abs) against pathogens or tumor antigens. B cells establish immune synapses with antigen-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf7d856a1c713afe3b8ab8e348915e11
https://doi.org/10.1158/2326-6074.tumimm17-b46
https://doi.org/10.1158/2326-6074.tumimm17-b46
Autor:
David G. Brooks, Cameron R. Cunningham, Jerold E. Rehg, Lynnea R. Waters, Michael A. Teitell, Herbert C. Morse, Jessica Fowler, Mark Lin, Nicole C Walsh
T‐cell‐dependent antigenic stimulation drives the differentiation of B cells into antibody‐secreting plasma cells and memory B cells, but how B cells regulate this process is unclear. We show that LKB1 expression in B cells maintains B‐cell q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507239640a5b86092f321454c8b8c66d
https://europepmc.org/articles/PMC4467859/
https://europepmc.org/articles/PMC4467859/
Publikováno v:
Cell Cycle. 14:2183-2184
Mature naive B cells are quiescent until activated by antigen receptor engagement. Once activated, follicular B cells rapidly proliferate and undergo immunoglobulin (IG) locus gene modifications to...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89dceb81356a61162af5d621920dc786
https://doi.org/10.1080/15384101.2015.1056610
https://doi.org/10.1080/15384101.2015.1056610