Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lynne V. Mayne"'
Publikováno v:
Alcoholism: Clinical and Experimental Research. 32:1186-1196
Background: The largest cause of neurological damage to children is prenatal exposure to alcohol and chronic alcohol use in adults is associated with neurodegeneration, dementia and long-term behavioral changes. Microarray analysis identified the DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586740b512ea03f07ba7c4268cc3688c
https://doi.org/10.1111/j.1530-0277.2008.00673.x
https://doi.org/10.1111/j.1530-0277.2008.00673.x
Publikováno v:
Brain Research. 1102:39-43
Studies analysing the effects of acute treatments on animal behaviour and brain biochemistry frequently use pairwise comparisons between sham-treated and -untreated animals. In this study, we analyse expression of tPA, Grik2, Smarca2 and the transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0d6bb31adf29186f4a7965360863ba
https://doi.org/10.1016/j.brainres.2006.05.011
https://doi.org/10.1016/j.brainres.2006.05.011
Publikováno v:
Genes, Brain and Behavior. 5:257-273
DNA microarray analysis was used to identify candidate ethanol-regulated genes, as a first step towards exploring how transcriptional changes might lead to ethanol-induced changes in behaviour. Mice were treated with a single acute intraperitoneal et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f245ed9374842701f53222d89fc05ce2
https://doi.org/10.1111/j.1601-183x.2005.00157.x
https://doi.org/10.1111/j.1601-183x.2005.00157.x
Publikováno v:
Molecular and Cellular Neuroscience. 13:119-130
Nerve growth factor (NGF)-induced differentiation of the rat pheochromocytoma, PC12, cell line presents a model system for the study of early gene expression changes involved in neuronal differentiation. Rapid alterations in mRNA expression patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f227907386a3ffc8998aadba91b634ba
https://doi.org/10.1006/mcne.1999.0736
https://doi.org/10.1006/mcne.1999.0736
Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: do the genes explain the diseases?
Autor:
Gilbert Chu, Lynne V. Mayne
Publikováno v:
Trends in Genetics. 12:187-192
Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy are three distinct human syndromes associated with sensitivity to ultraviolet radiation. We review evidence that these syndromes overlap with each other and arise from mutations in gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4591e5a869eb4453097c09d774950078
https://doi.org/10.1016/0168-9525(96)10021-4
https://doi.org/10.1016/0168-9525(96)10021-4
Publikováno v:
Experimental Cell Research. 223:308-313
The in vitro life span of human cells is under genetic control and limited. Immortalized cells, however, can be obtained at a low frequency following expression of the SV40 T antigen gene though the steps that lead to immortality are not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4402e6f151ba14b5b1ee301b4e311dc
https://doi.org/10.1006/excr.1996.0086
https://doi.org/10.1006/excr.1996.0086
Autor:
Lisa D. McDaniel, Roger A. Schultz, Karla A. Henning, Lynne V. Mayne, Michael S. Reagan, Miria Stefanini, Lei Li, Narayan V. Iyer, Randy J. Legerski, Errol C. Friedberg, Alan R. Lehmann
Publikováno v:
Cell. 82:555-564
The hereditary disease Cockayne syndrome (CS) is characterized by a complex clinical phenotype. CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. The cloned CSB gene encodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718c63715e164eca53106d2c08f2439e
https://doi.org/10.1016/0092-8674(95)90028-4
https://doi.org/10.1016/0092-8674(95)90028-4
Autor:
Lynne V. Mayne, Mike Hubank
Publikováno v:
Developmental Brain Research. 81:66-76
Expression of the human ERCC3 (excision repair cross-complementing) gene in cells from patients with xeroderma pigmentosum (XP) group B (XP-B) corrects the defect in repair of UV light-induced DNA damage. XP-B is one of three groups of XP which exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f032e8c7918fe291b4252443bc4ed67
https://doi.org/10.1016/0165-3806(94)90069-8
https://doi.org/10.1016/0165-3806(94)90069-8
AMPA receptor GluR2, but not GluR1, subunit deletion impairs emotional response conditioning in mice
Autor:
Stuart L. Rulten, Daniel Zamanillo, Claire I. Dixon, David N. Stephens, H.V. Morris, Andy N. Mead, Lynne V. Mayne
Publikováno v:
Behavioral neuroscience. 120(2)
Deletions of gria1 or gria2 genes encoding alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic-acid-receptor subunits differ in their effects on appetitive conditioning. The authors investigated whether similar differences would occur in an aversive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530e8acbc77df8e4912022fadefb1a8d
https://pubmed.ncbi.nlm.nih.gov/16719688
https://pubmed.ncbi.nlm.nih.gov/16719688
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 35(5)
Studies of brain cell function and physiology are hampered by the limited availability of immortal human brain-derived cell lines, as a result of the technical difficulties encountered in establishing immortal human cells in culture. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db0d35444f8d43d18a5a0a5a59cf08e
https://pubmed.ncbi.nlm.nih.gov/10475274
https://pubmed.ncbi.nlm.nih.gov/10475274