Výsledky vyhledávání - "Lynne P. Rutzky"

Purification of tumor-specific antigens. An overview of the relevance to human colon carcinoma

Autor: Lynne P. Rutzky, Barry D. Kahan, Neal R. Pellis, Margalit B. Mokyr, Baldwin H. Tom

Publikováno v: Cancer. 36:2449-2454

Methods which dissociate intramolecular noncovalent bonds have been used to prepare soluble derivatives of cell-surface antigens. Applications of these techniques to human colon carcinoma are underway. Continuous tissue-culture strains derived from p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d596a5981f3dcf429dcec15a10ca1490
https://doi.org/10.1002/1097-0142(197512)36:6<2449::aid-cncr2820360629>3.0.co

Zobrazit plný text záznamu

Novel sphingosine-1-phosphate receptor modulator KRP203 combined with locally delivered regulatory T cells induces permanent acceptance of pancreatic islet allografts

Autor: Lynne P. Rutzky, Stanislaw M. Stepkowski, Barry D. Kahan, Tammy Phan, Ronghai Deng, Mithun Khattar, Paul M. Schroder

Publikováno v: Transplantation. 95(7)

Background KRP203, a structural FTY720 analogue, has 5-fold greater selectivity for binding to sphingosine-1-phosphate receptor (S1PR) 1 (S1PR(1)) versus S1PR3 and 100-fold greater selectivity over S1PR(2) and S1PR(5). Although the immunoregulatory e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7240db4efe29d9c9af0ff8409401653
https://pubmed.ncbi.nlm.nih.gov/23545505

Zobrazit plný text záznamu

Challenges in Cyclosporine Therapy: The Role of Therapeutic Monitoring by Area Under the Curve Monitoring

Autor: Lynne P. Rutzky, Barry D. Kahan, Maria Welsh

Publikováno v: Therapeutic Drug Monitoring. 17:621-624

Cyclosporine has revolutionized the practice of transplantation, but its clinical application has been beclouded by a narrow therapeutic window between immunosuppressive and nephrotoxic concentrations. Marked intra-and interindividual pharmacokinetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1469d58b0323d14203317b11f442036f
https://doi.org/10.1097/00007691-199512000-00013

Zobrazit plný text záznamu

THE ABILITY OF PRETRANSPLANT TEST-DOSE PHARMACOKINETIC PROFILES TO REDUCE EARLY ADVERSE EVENTS AFTER RENAL TRANSPLANTATION1, 2

Autor: Stephen M. Katz, Joachim Grevel, C. T. Van Buren, Russell E. Lewis, Richard J. Knight, Barry D. Kahan, Maria Welsh, Kimberly L. Napoli, Lynne P. Rutzky

Publikováno v: Transplantation. 53:345-351

Pretransplant test-dose pharmacokinetic profiles were used to determine individual cyclosporine drug bioavailability and clearance rates in renal transplant patients. Assuming a linear relation between dose and area under the concentration curve (AUC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9540bef175f3087eae7735071d3b3b29
https://doi.org/10.1097/00007890-199202010-00016

Zobrazit plný text záznamu

Immature syngeneic dendritic cells potentiate tolerance to pancreatic islet allografts depleted of donor dendritic cells in microgravity culture condition

Autor: Tammy Phan, Stanislaw M. Stepkowski, Huimin Zhang, Yuhua Qi, Malgorzata Kloc, Szczepan M. Bilinski, Stephen M. Katz, Lynne P. Rutzky

Publikováno v: Transplantation. 82(12)

Background Previously we showed that pancreatic islets cultured for seven days in rotating bioreactors survived for >100 days in allogeneic recipients without immunosuppression. This survival coincided with almost complete elimination of "passenger"

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d26b51d3b99870dc62fac756b93d58
https://pubmed.ncbi.nlm.nih.gov/17198272

Zobrazit plný text záznamu

In vitro correlates of in vivo therapy with cyclosporine to immunosuppress rejection of heterotopic rat cardiac allografts across strong (RT-1) plus weak (non-RT-1) histocompatibility differences

Autor: Barry D. Kahan, Stanislaw M. Stepkowski, Lynne P. Rutzky, Joseph Lawen, Shuji Miyagawa

Publikováno v: Transplantation. 52(5)

This study correlated different oral cyclosporine doses with in vivo graft survival, blood and tissue drug levels, and in vitro immune performances. Wistar-Furth (WFu, RT-1u) hosts engrafted with heterotopic cardiac transplants from strongly histoinc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f09b2a6c2e64b52d215ee43dca384b0
https://pubmed.ncbi.nlm.nih.gov/1835196

Zobrazit plný text záznamu

IMPACT OF MICROGRAVITY CULTURE ON SURVIVAL OF ALLOGENEIC MOUSE PANCREATIC ISLET TRANSPLANTS

Autor: Tammy Phan, Stephen M. Katz, Lynne P. Rutzky, Szczepan M. Bilinski, Stanislaw M. Stepkowski, Haonan Zhang, Malgorzata Kloc

Publikováno v: Transplantation. 78:441

survival time of transplanted cells. Methods: 6weeks old male Nagase Analbuminemic rats (NAR) were injected subcutaneously every 3.5 days with CCl4 dissolved in equal volume of olive oil at a dose of 2.0 ml/kg body weight for 8weeks. Repeated intrapo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8e9057e21770885fbf581d4efca29ed
https://doi.org/10.1097/00007890-200407271-01180

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání