Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lynne Gilfillan"'
Autor:
Peter B Madrid, Sidharth Chopra, Ian D Manger, Lynne Gilfillan, Tiffany R Keepers, Amy C Shurtleff, Carol E Green, Lalitha V Iyer, Holli Hutcheson Dilks, Robert A Davey, Andrey A Kolokoltsov, Ricardo Carrion, Jean L Patterson, Sina Bavari, Rekha G Panchal, Travis K Warren, Jay B Wells, Walter H Moos, Raelyn L Burke, Mary J Tanga
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60579 (2013)
BACKGROUND: The rapid development of effective medical countermeasures against potential biological threat agents is vital. Repurposing existing drugs that may have unanticipated activities as potential countermeasures is one way to meet this importa
Externí odkaz:
https://doaj.org/article/8f664db31ceb45f1adcae9b7d13042df
Autor:
Mary J. Tanga, Amy C. Shurtleff, Lynne Gilfillan, Sina Bavari, Travis K. Warren, Peter B. Madrid, Robert A. Davey, Aaron N. Endsley, Andrey A. Kolokoltsov, Ian D. Manger, Carol E. Green, Rekha G. Panchal
Publikováno v:
ACS Infectious Diseases. 1:317-326
A systematic screen of FDA-approved drugs was performed to identify compounds with in vitro antiviral activities against Ebola virus (EBOV). Compounds active (>50% viral inhibition and
Autor:
Lutz Frank Schweiger, Andrew Sutherland, Adele Blair, Sally L. Pimlott, Judith A. Pratt, Brian J. Morris, Lynne Gilfillan
Publikováno v:
Med. Chem. Commun.. 4:1118-1123
A focused library of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones containing sites for 11C-, 18F- and 123I-labelling have been prepared and evaluated against membrane expressing human recombinant metabotropic glutamate 2 receptor (mGluR2). The compo
Autor:
Alison Harris, Katherine Anderson, Karen Tudge, Wendy Pepper, Helen Nutting, Lynne Perkins, Lynne Gilfillan, Dawn Griffiths
Publikováno v:
Patient Care.
Introduction The inpatient unit has introduced the three foundation modules from the Productive Ward programme, Patient Status at a Glance, The Well Organised Ward and Knowing How we are Doing. The project commenced in 2014 and continues to develop.
Publikováno v:
Drug Development Research. 70:327-334
In spite of significant increases in biodefense spending in the 7 years since the 2001 anthrax attacks, the United States may not yet be fully prepared to respond effectively to many potential biothreats. The principal reasons appear to be that: (1)
Publikováno v:
Drug Development Research. 70:303-326
Coordinated small-molecule drug discovery research efforts for the treatment of botulism by the public sector, especially the U.S. Department of Defense (DoD) and Department of Health and Human Services (DHHS), began in the 1990s and represent a sign
Autor:
Lynne Gilfillan, Alexander H. Harkiss, Raik Artschwager, Rob M. J. Liskamp, Andrew Sutherland
Publikováno v:
ChemInform. 46
Using the regioselective transformation of L-aspartic acid derived β-aryl α,β-unsaturated ketones (I) with phenyl hydrazine as a key step, a synthesis of pyrazole-containing α-amino acids (II) is developed.
Autor:
Lynne Gilfillan
Publikováno v:
Drug Development Research. 70:221-223
Autor:
Eric T. Jones, Larry A. Scarff, Lynne Gilfillan, Cullen Jackson, Stephanie Pratt, Shawn Weil, Dustin Burke, Stephen M. Fiore
Publikováno v:
SPIE Proceedings.
Most intelligence analysts currently use Information Products (IP) from multiple sources with very different characteristics to perform a variety of intelligence tasks. In order to maximize the analysts’ efficacy (and ultimately provide intelligent
Autor:
Robert A. Davey, Travis K. Warren, Jean L. Patterson, Rekha G. Panchal, Jay Wells, Mary J. Tanga, Sidharth Chopra, Carol E. Green, Tiffany R. Keepers, Lynne Gilfillan, Peter B. Madrid, Lalitha V. Iyer, Holli Hutcheson Dilks, Walter H. Moos, Sina Bavari, Ian D. Manger, RaeLyn L. Burke, Ricardo Carrion, Andrey A. Kolokoltsov, Amy C. Shurtleff
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60579 (2013)
PLoS ONE, Vol 8, Iss 4, p e60579 (2013)
BACKGROUND: The rapid development of effective medical countermeasures against potential biological threat agents is vital. Repurposing existing drugs that may have unanticipated activities as potential countermeasures is one way to meet this importa