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of 11
pro vyhledávání: '"Lynne Braidwood"'
Autor:
Leslee Sprague, Joel M. Lee, Brian J. Hutzen, Pin-Yi Wang, Chun-Yu Chen, Joe Conner, Lynne Braidwood, Kevin A. Cassady, Timothy P. Cripe
Publikováno v:
Viruses, Vol 10, Iss 3, p 132 (2018)
High Mobility Group Box 1 (HMGB1) is a multifunctional protein that plays various roles in the processes of inflammation, cancer, and other diseases. Many reports document abundant HMGB1 release following infection with oncolytic viruses (OVs). Furth
Externí odkaz:
https://doaj.org/article/49d4150dad95436fb37a92c1e24c853e
Autor:
Lynne Braidwood, Joe Conner, Kevin A. Cassady, Timothy P. Cripe, Fabian Benencia, Leslee Sprague
Publikováno v:
Future virology. 13(9)
Oncolytic viruses (OVs) do more than simply infect and kill host cells. The accepted mechanism of action for OVs consists of a primary lytic phase and a subsequent antitumor and antiviral immune response. However, not all cells are subject to the dir
Autor:
Joel M. Lee, Brian Hutzen, Chun-Yu Chen, Lynne Braidwood, Pin-Yi Wang, Joe Conner, Timothy P. Cripe, Leslee Sprague, Kevin A. Cassady
Publikováno v:
Viruses
Viruses; Volume 10; Issue 3; Pages: 132
Viruses, Vol 10, Iss 3, p 132 (2018)
Viruses; Volume 10; Issue 3; Pages: 132
Viruses, Vol 10, Iss 3, p 132 (2018)
High Mobility Group Box 1 (HMGB1) is a multifunctional protein that plays various roles in the processes of inflammation, cancer, and other diseases. Many reports document abundant HMGB1 release following infection with oncolytic viruses (OVs). Furth
Publikováno v:
ResearcherID
The 8th International Conference on Oncolytic Virus Therapeutics meeting was held from April 10–13, 2014, in Oxford, United Kingdom. It brought together experts in the field of oncolytics from Europe, Asia, Australasia, and the Americas and provide
Publikováno v:
Journal of Hepatocellular Carcinoma
Lynne Braidwood, Kirsty Learmonth, Alex Graham, Joe Conner Virttu Biologics Ltd, Department of Neurology, Southern General Hospital, Glasgow, UK Abstract: Oncolytic herpes simplex virus (HSV1716), lacking the neurovirulence factor ICP34.5, has highly
Publikováno v:
Oncolytic Virotherapy, Vol 2013, Iss Issue 1, Pp 57-74 (2013)
Oncolytic Virotherapy
Oncolytic Virotherapy
Lynne Braidwood,1 Sheila V Graham,2 Alex Graham,1 Joe Conner11Virttu Biologics Ltd, Department of Neurology, Southern General Hospital, Glasgow, UK; 2MRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammati
Autor:
Moira Brown, Annette Sorensen, Lynne Braidwood, Joe Conner, Sally L. Pimlott, Craig Joyce, Marie Boyd, Robert J. Mairs
Publikováno v:
Journal of Nuclear Medicine. 53:647-654
Oncolytic herpes viruses show promise for cancer treatment. However, it is unlikely that they will fulfill their therapeutic potential when used as monotherapies. An alternative strategy is to use these viruses not only as oncolytic agents but also a
Publikováno v:
Cancer Immunology Research. 4:B033-B033
Malignant pleural mesothelioma (MPM) remains a major challenge, with limited therapeutic options. Multifocal intrapleural disease can cause disabling symptoms of pain and breathlessness, in the absence of distant metastases, so an intrapleural treatm
Publikováno v:
Gene therapy. 15(24)
We report on the ability of single-chain variable fragment (scFv) incorporated into the viral envelope to alter the tropism of herpes simplex virus (HSV) 1716. Using recombinant viruses expressing fusion proteins comprising cell-surface antigen-speci
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Malignant pleural mesothelioma (MPM) remains a major challenge, with limited therapeutic options. Multifocal intrapleural disease can cause disabling symptoms of pain and breathlessness, in the absence of distant metastases, so an i