Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lynne Baxter"'
Autor:
Rachel Waller, Lynne Baxter, Daniel J Fillingham, Santiago Coelho, Jose M Pozo, Meghdoot Mozumder, Alejandro F Frangi, Paul G Ince, Julie E Simpson, J Robin Highley
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210888 (2019)
Deep subcortical lesions (DSCL) of the brain, are present in ~60% of the ageing population, and are linked to cognitive decline and depression. DSCL are associated with demyelination, blood brain barrier (BBB) dysfunction, and microgliosis. Microglia
Externí odkaz:
https://doaj.org/article/bf9ba81364ba489bb1902dc093d4234a
Autor:
Daniel J. Fillingham, Paul G. Ince, Santiago Coelho, Meghdoot Mozumder, Jose M. Pozo, Lynne Baxter, Rachel Waller, Alejandro F. Frangi, J. Robin Highley, Julie E. Simpson
Publikováno v:
PLoS ONE
Publons
PLoS ONE, Vol 14, Iss 1, p e0210888 (2019)
Publons
PLoS ONE, Vol 14, Iss 1, p e0210888 (2019)
Deep subcortical lesions (DSCL) of the brain, are present in ~60% of the ageing population, and are linked to cognitive decline and depression. DSCL are associated with demyelination, blood brain barrier (BBB) dysfunction, and microgliosis. Microglia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41363d578afa10ec6f5685af90540551
https://pubmed.ncbi.nlm.nih.gov/30682074
https://pubmed.ncbi.nlm.nih.gov/30682074
Autor:
Julie E. Simpson, Fiona E. Matthews, Stephen B. Wharton, Carol Brayne, Catherine Gelsthorpe, Pamela J. Shaw, Paul G. Ince, Adnan Faizullabhoy, Lynne Baxter, Paul R. Heath, G. Forster, Claire J. Garwood
Publikováno v:
Neuropathology and Applied Neurobiology. 39:788-799
Aims Calcium dyshomeostasis is implicated in the pathogenesis of several neurodegenerative disorders including Alzheimer's disease. However, much of the previous research has focused on changes in neuronal calcium signalling. In a recent microarray s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b30883f94bc0e7a0c73a125e733bb00
https://doi.org/10.1111/nan.12033
https://doi.org/10.1111/nan.12033
Autor:
George M. Savva, Carol Brayne, James R. Cooper, Gillian Forster, Lynne Baxter, Paul G. Ince, Julie E. Simpson, Pamela J. Shaw, Fiona E. Matthews, Catherine Gelsthorpe, Stephen B. Wharton
Publikováno v:
Neuroscience Letters. 486:246-251
White matter lesions (WML) are associated with dementia and are common in brain ageing. In order to determine whether alteration of the blood-brain barrier (BBB) may contribute to the pathogenesis of WML we assessed albumin leakage and expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4c0761c824a006fa8cd9a921e09464
https://doi.org/10.1016/j.neulet.2010.09.063
https://doi.org/10.1016/j.neulet.2010.09.063
Autor:
Catherine Gelsthorpe, Stephen B. Wharton, Anthony L. Johnson, Gareth H. Williams, Kai Stoeber, Lynne Baxter, Paul G. Ince
Publikováno v:
Neuroscience Letters. 383:33-38
Cell-cycle mechanisms may be aberrantly reactivated in the ageing brain and associated with the development of pathology, including Alzheimer's disease. Activation of cell-cycle mechanisms in glia has, however, been little studied. Our aim was to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f763899a02f7dd52e23ae84c0fba0b5e
https://doi.org/10.1016/j.neulet.2005.04.019
https://doi.org/10.1016/j.neulet.2005.04.019
Autor:
Lynne Baxter, Gavin Jack
Publikováno v:
Academy of Management Proceedings. 2004:D1-D6
We explore the concept of parrhesia meaning truth telling or frank speaking (Foucault, 2001). Two cases are presented to illustrate some of the problems of truth-telling in research settings and in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::967713efe671e45a643cc04daff349d4
https://doi.org/10.5465/ambpp.2004.13857432
https://doi.org/10.5465/ambpp.2004.13857432
Autor:
Theresa Walsh, John Hardy, Christopher J. Hewitt, Johnathan Cooper-Knock, Melanie Fox, Stephen B. Wharton, Joanna J. Bury, Joanne Martindale, Somai Man, Judith Hartley, Paul G. Ince, Janine Kirby, Gillian Forster, Alice Brockington, Pamela J. Shaw, Kin Y. Mok, Bryan J. Traynor, J. Robin Highley, Antonio Milano, Catherine Gelsthorpe, Lynne Baxter, Christopher J McDermott
Publikováno v:
Brain; Vol 135
Intronic expansion of the GGGGCC hexanucleotide repeat within the C9ORF72 gene causes frontotemporal dementia and amyotrophic lateral sclerosis/motor neuron disease in both familial and sporadic cases. Initial reports indicate that this variant withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbe92a9c69e5bca7bd8b2083e24a4aa
https://pubmed.ncbi.nlm.nih.gov/22366792
https://pubmed.ncbi.nlm.nih.gov/22366792
Autor:
Stephen B. Wharton, Pamela J. Shaw, Catherine Gelsthorpe, Julie E. Simpson, Fiona E. Matthews, Paul G. Ince, Gillian Forster, Claire J. Garwood, Lynne Baxter, Rohini Raman, Paul R. Heath, Carol Brayne
Publikováno v:
Neurobiology of aging. 32(10)
Astrocytes contribute to a variety of functions in the brain, including homeostasis, synapse formation, plasticity, and metabolism. Astrocyte dysfunction may disrupt their normal role, including neuronal support, thereby contributing to neurodegenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579b904a0d5682f00620ee638154ede3
https://pubmed.ncbi.nlm.nih.gov/21705112
https://pubmed.ncbi.nlm.nih.gov/21705112
Autor:
Paul G. Ince, R. Theaker, Stephen B. Wharton, L. J. Haynes, G Lace, Catherine Gelsthorpe, Lynne Baxter, Julie E. Simpson, Fiona E. Matthews, George M. Savva, G. Forster, Pamela J. Shaw, Carol Brayne
Publikováno v:
Neuropathology and applied neurobiology. 36(1)
Increasing evidence suggests a role for oxidative damage to DNA in brain ageing and in neurodegenerative disorders, including Alzheimer's disease. Most studies have focussed on the reduced capacity for DNA repair by neurones, and have not taken into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49e2f22f8a0c1b1e78be97744b3c3a0
https://pubmed.ncbi.nlm.nih.gov/19422529
https://pubmed.ncbi.nlm.nih.gov/19422529
Autor:
Lynne Baxter
Publikováno v:
Journal of Manufacturing Technology Management. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4927173d76bf3662aa6d4319ef6281
https://doi.org/10.1108/jmtm.2007.06818faa.001
https://doi.org/10.1108/jmtm.2007.06818faa.001