Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lynne A. Hay"'
Autor:
Thomas M. Koenig, James E. Audia, Mcdaniel Stacey L, Lynne A. Hay, Nissen Jeffrey S, David Mitchell
Publikováno v:
Tetrahedron: Asymmetry. 16:3814-3819
Two efficient production processes of enantioenriched 1-amino-3-methyl-1,3,4,5-tetrahydro-benzo[d]azepin-2-one 1 were achieved using the readily available starting materials. A key step in the methodologies is a classical resolution or a dynamic reso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b276dba997f406b301b16e23ad69ec3
https://doi.org/10.1016/j.tetasy.2005.10.037
https://doi.org/10.1016/j.tetasy.2005.10.037
Publikováno v:
The Journal of Organic Chemistry. 63:5050-5058
A general regio- and stereoselective synthesis of 3,3-diarylacrylamides is reported. Palladium-catalyzed coupling reactions of propiolamides with aryl halides provide arylpropiolamides. A subsequent hydroarylation reaction of these arylpropiolamides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da0b91b7430110fc8fc297f274ebe764
https://doi.org/10.1021/jo980235h
https://doi.org/10.1021/jo980235h
Autor:
Lynne A. Hay, David Mitchell
Publikováno v:
Tetrahedron Letters. 38:6533-6536
Palladium-catalyzed hydroarylation of acetylenes provides regio- and stereodefined olefins. This methodology has been extended to arylpropiolamides where 3,3-diarylacrylamides are prepared stereospecifically. In an independent fashion, both the E- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c20ba62aab35cbeab7476ba90c5990
https://doi.org/10.1016/s0040-4039(97)01528-1
https://doi.org/10.1016/s0040-4039(97)01528-1
Publikováno v:
ChemInform. 26
A method for the selective protection of polyphenolic hydroxyls is described. This approach relies on the deoxygenation of a benzylic ketone ortho to at least one of the phenolic hydroxyl groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bf1ec646bf7c658d5bede063ba2095
https://doi.org/10.1002/chin.199544065
https://doi.org/10.1002/chin.199544065
Autor:
Lynne A. Hay, David Mitchell
Publikováno v:
ChemInform. 28
Palladium-catalyzed hydroarylation of acetylenes provides regio- and stereodefined olefins. This methodology has been extended to arylpropiolamides where 3,3-diarylacrylamides are prepared stereospecifically. In an independent fashion, both the E- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c11550b3d367d0b20040525b03b9c479
https://doi.org/10.1002/chin.199749113
https://doi.org/10.1002/chin.199749113
Publikováno v:
ChemInform. 29
A general regio- and stereoselective synthesis of 3,3-diarylacrylamides is reported. Palladium-catalyzed coupling reactions of propiolamides with aryl halides provide arylpropiolamides. A subsequent hydroarylation reaction of these arylpropiolamides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b57848727023b606443a7fd5594e7281
https://doi.org/10.1002/chin.199850111
https://doi.org/10.1002/chin.199850111
Autor:
Thomas M. Koenig, Charles Lugar, Jeffery A. Dodge, Kathy K. Ellis, Lynne A. Hay, Erin E. Strouse, David Mitchell
Publikováno v:
ACS Symposium Series ISBN: 9780841237438
From Bench to Pilot Plant: Process Research in the Pharmaceutical Industry
From Bench to Pilot Plant: Process Research in the Pharmaceutical Industry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ad0566d745a98f0e8d4ae5a8f53217
https://doi.org/10.1021/bk-2002-0817.ch009
https://doi.org/10.1021/bk-2002-0817.ch009
Autor:
Richard D. Towner, Robert Theodore Shuman, David K. Herron, Jeffry Bernard Franciskovich, John Joseph Masters, Michael Robert Wiley, Kenneth D. Kurz, T. C. Smith, Andrew Michael Ratz, and Alex Wilson, Jack B. Campbell, Charles S. Campbell, Valentine J. Klimkowski, Larry L. Froelich, Donetta S. Gifford-Moore, Ying K. Yee, James T. Metz, Lynne A. Hay, Jennifer M. Tinsley, Trelia J. Craft, Gerald F. Smith
Publikováno v:
Journal of medicinal chemistry. 43(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76485681978c2e13a430bfab36e8be0
https://pubmed.ncbi.nlm.nih.gov/10841787
https://pubmed.ncbi.nlm.nih.gov/10841787
Autor:
Mehdi Nafissi, Nikolaos H . Petousis, Edward J. J. Grabowski, Matthew J. Sharp, Mark W. Andersen, Evan G. Boswell, Bobby N. Glover, Michael T. Martin, Richard T. Matsuoka, Xiaoming Zhou, David M. Barnes, Jianguo Ji, Ji Zhang, Steven A. King, Steven J. Wittenberger, Howard E. Morton, Roger N. Brummel, Lawrence E. Fisher, Charles Dvorak, Keena Green, Samantha Janisse, Anthony Prince, Keshab Sarma, Paul McGrane, David Moore, Jeffrey Campbell, Janel Baptista, Chris Broka, Than Hendricks, Keith Walker, Calvin Yee, Michael F. Lipton, Michael A. Mauragis, Michael F. Veley, Gordon L. Bundy, Lee S. Banitt, Paul J. Dobrowolski, John R. Palmer, Theresa M. Schwartz, David C. Zimmerman, Keith M. DeVries, Jeffery A. Dodge, Kathy K. Ellis, Lynne A. Hay, Thomas M. Koenig, Charles Lugar, Erin E. Strouse, David Mitchell