Výsledky vyhledávání - "Lynne, Johnson"

Akademický článek

Effect of Active Workstations on Neurocognitive Performance and Typing Skills: A Randomized Clinical Trial

Autor: Jose R. Medina‐Inojosa, Miguel A. Gomez Ibarra, Betsy J. Medina‐Inojosa, Marta Supervia, Sarah Jenkins, Lynne Johnson, Nathalie P. Suarez, Amanda Bonikowske, Virend K. Somers, Francisco Lopez‐Jimenez

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)

Background Extended sedentary behavior is a risk factor for chronic disease and mortality, even among those who exercise regularly. Given the time constraints of incorporating physical activity into daily schedules, and the high likelihood of sitting

Externí odkaz: https://doaj.org/article/76f30f77b2424ba096bcfdd12123c385

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A comparison of the Woman-centred care: strategic directions for Australian maternity services (2019) national strategy with other international maternity plans

Autor: Hannah Grace, Dahlen, Simone, Ormsby, Alecia, Staines, Mary, Kirk, Lynne, Johnson, Kirsten, Small, Bashi, Hazard, Virginia, Schmied

Publikováno v: Women and Birth. 36:17-29

In 2019 the Australian government released a guiding document for maternity care: Woman-centred care strategic directions for Australian maternity services (WCC Strategy), with mixed responses from providers and consumers. The aims of this paper were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7884fd8f86600cc2530b9997b2498875
https://doi.org/10.1016/j.wombi.2022.04.003

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Akademický článek

EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling

Autor: Catrina M Loucks, Kwangjin Park, Denise S Walker, Andrea H McEwan, Tiffany A Timbers, Evan L Ardiel, Laura J Grundy, Chunmei Li, Jacque-Lynne Johnson, Julie Kennedy, Oliver E Blacque, William Schafer, Catharine H Rankin, Michel R Leroux

Publikováno v: eLife, Vol 8 (2019)

Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles of cilia in these neurons are poorly understood. To shed light into their functions, we stu

Externí odkaz: https://doaj.org/article/187f16f490b2476e89b17a0470140d3f

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Association of Tumor Mutational Burden and Immune Gene Expression with Response to PD-1 Blockade by Sasanlimab Across Tumor Types and Routes of Administration

Autor: Alison Forgie, Melissa Lynne Johnson, Jeffrey Chou, Ira Jacobs, Xiao Wang, Siwen Hu-Lieskovan, Juneko E. Grilley-Olson, Fadi Braiteh, Vinicius Bonato

Publikováno v: Targeted Oncology

Background Sasanlimab is a monoclonal antibody that binds to the programmed cell death receptor 1 (PD-1). Anti-PD-1 monoclonal antibodies have improved patient clinical outcomes; however, not all treated patients derive clinical benefit. Further insi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0360bf7852af5093e8cae4fa08622e
https://doi.org/10.1007/s11523-021-00833-2

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Efficacy and Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor–Resistant, EGFR-Mutated Non–Small Cell Lung Cancer

Publikováno v: Cancer Discovery. 12:74-89

Receptor tyrosine-protein kinase ERBB3 (HER3) is expressed in most EGFR-mutated lung cancers but is not a known mechanism of resistance to EGFR inhibitors. HER3-DXd is an antibody–drug conjugate consisting of a HER3 antibody attached to a topoisome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3f21e2b203037b25e1755b222753df4
https://doi.org/10.1158/2159-8290.cd-21-0715

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A Phase 1–2 Study of Rovalpituzumab Tesirine in Combination With Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Extensive-Stage SCLC

Autor: John Wrangle, Ticiana Leal, Gilles Robinet, Neal Ready, David Maag, Jyoti Malhotra, Melissa Lynne Johnson, Satwant Lally, Petros Nikolinakos, Jyoti D. Patel, Daniel Morgensztern, Benjamin Besse, Vincent Blot, Giuseppe Curigliano, Ricardo Valenzuela, Laurent Greillier, Jonathan M. Lehman

Publikováno v: Journal of Thoracic Oncology
Journal of Thoracic Oncology, 2021, 16 (9), pp.1559-1569. ⟨10.1016/j.jtho.2021.02.022⟩

Introduction This open-label, phase 1–2 study evaluated the safety and efficacy of rovalpituzumab tesirine (Rova-T), an antibody-drug conjugate targeting DLL3, plus immune checkpoint inhibitors nivolumab plus or minus ipilimumab in previously treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c2323534cecd409bf8ef57951bfa24
https://doi.org/10.1016/j.jtho.2021.02.022

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A Phase Ib Open-Label, Multicenter Study of Inhaled DV281, a TLR9 Agonist, in Combination with Nivolumab in Patients with Advanced or Metastatic Non–small Cell Lung Cancer

Autor: Amy L. Cummings, Lyudmila Bazhenova, Edward B. Garon, Melissa Lynne Johnson, Alexander I. Spira, Joseph Leach, Mary J. Janatpour, Robert L. Coffman, Laura Q.M. Chow, Erick Gamelin, Albert Candia, Robert Janssen

Publikováno v: Clinical Cancer Research. 27:4566-4573

Purpose: Although PD-(L)1 inhibitors have shown efficacy in advanced/metastatic non–small cell lung cancer (NSCLC), many patients do not respond to this treatment and more effective combinations with acceptable toxicities are needed. To assess the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e7cd238ce472904696326bf7365e55
https://doi.org/10.1158/1078-0432.ccr-21-0263

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Phase I, First-in-Human Study of the Probody Therapeutic CX-2029 in Adults with Advanced Solid Tumor Malignancies

Autor: Mark Stroh, Melissa Lynne Johnson, Henry Castro, Jordi Rodon, Alexander I. Spira, Rachel E. Sanborn, Hirva Mamdani, Nehal Lakhani, Anthony B. El-Khoueiry, Song Wang, Navid Hafez, Valentina Boni, Alison L. Hannah, Javier Garcia-Corbacho

Publikováno v: Clinical Cancer Research. 27:4521-4530

Purpose: PROCLAIM-CX-2029 is a phase I first-in-human study of CX-2029, a Probody–drug conjugate targeting CD71 (transferrin receptor 1) in adults with advanced solid tumors. Although the transferrin receptor is highly expressed across multiple tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8daa9e1644559f55f6d2d1e18ab7eb2
https://doi.org/10.1158/1078-0432.ccr-21-0194

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Promising Educational Technology Meets Complex System: a 6-year Case Study of an Adaptive Learning Project from Initial Exploration Through the End of a Pilot

Autor: Eunsung Park, Jessica Resig, Phil Stuczynski, Lynne Johnson, Junxiu Yu, Andrea Gregg

Publikováno v: Journal of Formative Design in Learning. 5:62-77

Instructional designers (IDs) are charged with what some might argue is the impossible: implementing innovative technologies and new pedagogical approaches within complex systems that often implicitly discourage change. This 6-year case study examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01bec639851d8a43e5080aeccf15a470
https://doi.org/10.1007/s41686-021-00057-7

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