Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lynn-Jee Kim"'
Autor:
Michael J. Bertoldo, Dave R. Listijono, Wing-Hong Jonathan Ho, Angelique H. Riepsamen, Dale M. Goss, Dulama Richani, Xing L. Jin, Saabah Mahbub, Jared M. Campbell, Abbas Habibalahi, Wei-Guo Nicholas Loh, Neil A. Youngson, Jayanthi Maniam, Ashley S.A. Wong, Kaisa Selesniemi, Sonia Bustamante, Catherine Li, Yiqing Zhao, Maria B. Marinova, Lynn-Jee Kim, Laurin Lau, Rachael M. Wu, A. Stefanie Mikolaizak, Toshiyuki Araki, David G. Le Couteur, Nigel Turner, Margaret J. Morris, Kirsty A. Walters, Ewa Goldys, Christopher O’Neill, Robert B. Gilchrist, David A. Sinclair, Hayden A. Homer, Lindsay E. Wu
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1670-1681.e7 (2020)
Summary: Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of oocyte quality with age accompanies declining levels of
Externí odkaz:
https://doaj.org/article/a90efaf77b4241cf832c48855e659c9a
Autor:
Lynn-Jee Kim, Lindsay E. Wu, Lake-Ee Quek, Josephine Yu, Margaret J. Morris, Neil A. Youngson, D. R. Laybutt
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 321(1)
NMN dampened exercise-induced benefits on glucose handling in diet-induced obesity. NMN administration alongside treadmill exercise enhanced the ratio of antioxidants to prooxidants. We suggest that NMN administration may not be beneficial when NAD+
Autor:
Simon P. Tucker, Greg C. Smith, David A. Sinclair, Abhirup Das, Lindsay E. Wu, Lake-Ee Quek, Wing Keung Eric Poon, Timothy J. Chalmers, Lynn-Jee Kim, Catherine Li, Jun Wang
Treatment with nicotinamide mononucleotide (NMN) is a prominent strategy to address the age-related decline in nicotinamide adenine dinucleotide (NAD+) levels for maintaining aspects of late-life health. It is assumed that exogenous NMN is directly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96bfc69708ae0840ba0b0714ffd56d90
https://doi.org/10.21203/rs.3.rs-87047/v1
https://doi.org/10.21203/rs.3.rs-87047/v1
Autor:
Lynn-Jee Kim, Timothy J. Chalmers, Romanthi Madawala, Greg C. Smith, Catherine Li, Abhirup Das, Eric Wing Keung Poon, Jun Wang, Simon P. Tucker, David A. Sinclair, Lake-Ee Quek, Lindsay E. Wu
Treatment with nicotinamide mononucleotide (NMN) is a prominent strategy to address the age-related decline in nicotinamide adenine dinucleotide (NAD+) levels for maintaining aspects of late-life health. It is assumed that exogenous NMN is directly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1c84d58baf297d83258186b68cbbe1
https://doi.org/10.1101/2020.09.10.289561
https://doi.org/10.1101/2020.09.10.289561
Autor:
Lindsay E. Wu, D. Ross Laybutt, Lynn-Jee Kim, Margaret J. Morris, Neil A. Youngson, Josephine Yu, Lake-Ee Quek
ObjectiveAlmost 40% of adults worldwide are classified as overweight or obese. Exercise is a beneficial intervention in obesity, partly due to increases in mitochondrial activity, with a potential role for the concomitant increase in nicotinamide ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e161bb5572d76bb4d8c56d3e989f1fdc
https://doi.org/10.1101/2020.06.22.164459
https://doi.org/10.1101/2020.06.22.164459
Autor:
Michael J. Bertoldo, Kirsty A Walters, Kaisa Selesniemi, Robert B. Gilchrist, A. Stefanie Mikolaizak, Wei-Guo Nicholas Loh, Yiqing Zhao, Chris O'Neill, Abbas Habibalahi, Jared M. Campbell, Lynn-Jee Kim, Maria B. Marinova, Ashley S.A. Wong, Jayanthi Maniam, Dave R. Listijono, David G. Le Couteur, Xing L. Jin, Dulama Richani, Margaret J. Morris, Saabah B. Mahbub, Lindsay E. Wu, Catherine Li, Hayden Homer, Wing-Hong Jonathan Ho, Laurin Lau, Toshiyuki Araki, Dale M. Goss, Neil A. Youngson, David A. Sinclair, Rachael M. Wu, Nigel Turner, Angelique H. Riepsamen, Ewa M. Goldys
Female infertility is a common and devastating condition with life-long health, emotional and social consequences. There is currently no pharmacological therapy for preserving oocyte quality during aging, which is the strongest risk factor for infert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c1c6d376e8aabdfe6da5bf2056367a
https://doi.org/10.1101/721985
https://doi.org/10.1101/721985
Autor:
Ewa M. Goldys, Hayden Homer, Toshiyuki Araki, Jayanthi Maniam, Yiqing Zhao, Laurin Lau, Abbas Habibalahi, David G. Le Couteur, Saabah B. Mahbub, Lindsay E. Wu, A. Stefanie Mikolaizak, Margaret J. Morris, Dale M. Goss, Chris O'Neill, Dave R. Listijono, Kirsty A Walters, Xing L. Jin, Maria B. Marinova, Wei-Guo Nicholas Loh, Sonia Bustamante, David A. Sinclair, Jared M. Campbell, Lynn-Jee Kim, Rachael M. Wu, Nigel Turner, Angelique H. Riepsamen, Ashley S.A. Wong, Neil A. Youngson, Robert B. Gilchrist, Michael J. Bertoldo, Kaisa Selesniemi, Catherine Li, Wing-Hong Jonathan Ho, Dulama Richani
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1670-1681.e7 (2020)
Cell reports
Cell reports
SUMMARY Reproductive aging in female mammals is an irreversible process associated with declining oocyte quality, which is the rate-limiting factor to fertility. Here, we show that this loss of oocyte quality with age accompanies declining levels of
Autor:
Myung-Jin Kang, Lynn-Jee Kim, Brendan Lee, Brenna Osborne, George X. Huang, James R. Mitchell, Alban Longchamp, Michael B. Schultz, Jose Humberto Treviño-Villarreal, Lindsay E. Wu, Yuancheng Lu, Nigel Turner, David A. Sinclair, Catherine Li, Abhirup Das, Zolt Arany, Tzong-Tyng Hung, Masaki Igarashi, Eric O. Williams, Sanket Joshi, Leonard Guarente, Michael Bonkowski
Publikováno v:
PMC
A decline in capillary density and blood flow with age is a major cause of mortality and morbidity. Understanding why this occurs is key to future gains in human health. NAD precursors reverse aspects of aging, in part, by activating sirtuin deacylas
Autor:
Gilchrist, Robert, Ho, Wing-Hong Jonathan, Marinova, Maria B, Listijono, Dave R, Bertoldo, Michael J, Richani, Dulama, Lynn-Jee, Kim, Brown, Amelia, Riepsamen, Angelique H, Cabot, Safaa, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Goss, Dale M, Li, Catherine, Araki, Toshiyuki, Livingston, David J, Turner, Nigel, Sinclair, David A, Walters, Kirsty A, Homer, Hayden A, Wu, Lindsay E
Publikováno v:
Fertility & Reproduction; December 2023, Vol. 5 Issue: 4 p518-518, 1p