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of 2
pro vyhledávání: '"Lynn Varacallo"'
Autor:
Peter Taggart, Jean McCarthy, S. Jim Proctor, Erin Saleh, L. Mark Kao, Angelique M. Leone, Lynn Varacallo, Michael K. McMillian, Kelley Michael F, Monica Singer
Publikováno v:
Advances in Bioscience and Biotechnology. :216-229
Idiosyncratic hepatotoxicity accounts for many drug failures in the clinic and is a leading cause for black-boxed and withdrawn drugs. This toxicity has proven difficult to predict preclinically, but correlates with oxidative stress/reactive metaboli
Autor:
Calvert Louden, Manisha Sonee, James Eric McDuffie, Sandra Snook, Antonio Guy, Xuejun Liu, Marciano Sablad, Lynn Varacallo, David La, Jennifer Vegas, Jing Ying Ma
Publikováno v:
International Journal of Toxicology. 32:251-260
Cisplatin (CDDP) is known to produce renal proximal tubule injury. Various renal biomarkers have been related to CDDP nephrotoxicity in previous research, but the temporal and spatial relationship of these biomarkers to injury reversal has not been w