Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Lynn T. Landmesser"'
Autor:
Alicia N. Vagnozzi, Matthew T. Moore, Raquel López de Boer, Aambar Agarwal, Niccolò Zampieri, Lynn T. Landmesser, Polyxeni Philippidou
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Phrenic Motor Column (PMC) neurons are a specialized subset of motor neurons (MNs) that provide the only motor innervation to the diaphragm muscle and are therefore essential for survival. Despite their critical role, the mechanisms that control phre
Externí odkaz:
https://doaj.org/article/e28848f099e34714bd9c31f283e31604
A Latent Propriospinal Network Can Restore Diaphragm Function after High Cervical Spinal Cord Injury
Autor:
Jared M. Cregg, Kevin A. Chu, Lydia E. Hager, Rachel S.J. Maggard, Daimen R. Stoltz, Michaela Edmond, Warren J. Alilain, Polyxeni Philippidou, Lynn T. Landmesser, Jerry Silver
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 654-665 (2017)
Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excita
Externí odkaz:
https://doaj.org/article/994ec695c1454270848206c7b3bfa16f
Autor:
Alicia N Vagnozzi, Kiran Garg, Carola Dewitz, Matthew T Moore, Jared M Cregg, Lucie Jeannotte, Niccolò Zampieri, Lynn T Landmesser, Polyxeni Philippidou
Publikováno v:
eLife, Vol 9 (2020)
The precise pattern of motor neuron (MN) activation is essential for the execution of motor actions; however, the molecular mechanisms that give rise to specific patterns of MN activity are largely unknown. Phrenic MNs integrate multiple inputs to me
Externí odkaz:
https://doaj.org/article/8012e740220a4b9193c80bdb0b4cac01
Autor:
Alicia N Vagnozzi, Matthew T Moore, Minshan Lin, Elyse M Brozost, Ritesh KC, Aambar Agarwal, Lindsay A Schwarz, Xin Duan, Niccolò Zampieri, Lynn T Landmesser, Polyxeni Philippidou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cb86ffec8d021db9f8f5a9f1ba81a0
https://doi.org/10.7554/elife.82116.sa2
https://doi.org/10.7554/elife.82116.sa2
Autor:
Carola Dewitz, Matthew T Moore, Lynn T. Landmesser, Niccolò Zampieri, Jared M. Cregg, Polyxeni Philippidou, Lucie Jeannotte, Alicia N Vagnozzi, Kiran Garg
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The precise pattern of motor neuron (MN) activation is essential for the execution of motor actions; however, the molecular mechanisms that give rise to specific patterns of MN activity are largely unknown. Phrenic MNs integrate multiple inputs to me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c7af20d117c859c1c323c39442a02e
https://doi.org/10.7554/elife.52859
https://doi.org/10.7554/elife.52859
Autor:
Jared M. Cregg, Matthew T Moore, Niccolò Zampieri, Polyxeni Philippidou, Alicia N Vagnozzi, Carola Dewitz, Kiran Garg, Lynn T. Landmesser, Lucie Jeannotte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b386843015ea2d7271f6348a7728306a
https://doi.org/10.7554/elife.52859.sa2
https://doi.org/10.7554/elife.52859.sa2
Publikováno v:
The Journal of Neuroscience. 38:498-510
The neural cell adhesion molecule (NCAM) is expressed both presynaptically and postsynaptically during neuromuscular junction formation. Genetic deletion in mice of all three isoforms (180, 140, and 120 kDa), or just the 180 isoform, suggested that d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168c8e609c83196e0a0754de387389d1
https://doi.org/10.1523/jneurosci.1014-17.2017
https://doi.org/10.1523/jneurosci.1014-17.2017
Publikováno v:
Proceedings of the National Academy of Sciences. 114:12815-12820
Central neural networks operate continuously throughout life to control respiration, yet mechanisms regulating ventilatory frequency are poorly understood. Inspiration is generated by the pre-Botzinger complex of the ventrolateral medulla, where it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516246210666e7bd18c37a7a7d457a65
https://doi.org/10.1073/pnas.1711536114
https://doi.org/10.1073/pnas.1711536114
A Latent Propriospinal Network Can Restore Diaphragm Function after High Cervical Spinal Cord Injury
Autor:
Kevin A. Chu, Lydia E. Hager, Michaela Edmond, Daimen Stoltz, Rachel S.J. Maggard, Lynn T. Landmesser, Jared M. Cregg, Jerry Silver, Polyxeni Philippidou, Warren J. Alilain
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 654-665 (2017)
Spinal cord injury (SCI) above cervical level 4 disrupts descending axons from the medulla that innervate phrenic motor neurons, causing permanent paralysis of the diaphragm. Using an ex vivo preparation in neonatal mice, we have identified an excita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffee31281307be30cdbc3667fc6f3e5a
https://pubmed.ncbi.nlm.nih.gov/29045834
https://pubmed.ncbi.nlm.nih.gov/29045834
Publikováno v:
The Journal of Neuroscience. 30:12005-12019
Spinal muscular atrophy (SMA) is a common (∼1:6400) autosomal recessive neuromuscular disorder caused by a paucity of the survival of motor neuron (SMN) protein. Although widely recognized to cause selective spinal motor neuron loss when deficient,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e555a7082b71e1474f21334b7af13810
https://doi.org/10.1523/jneurosci.2208-10.2010
https://doi.org/10.1523/jneurosci.2208-10.2010