Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lynn S. Taylor"'
Publikováno v:
The Journal of Immunology. 176:6615-6623
Activating, DAP12-coupled members of the Ly-49 family of NK cell receptors help control viral infections in mice. However, the kinases and/or phosphatases mediating tyrosine phosphorylation of Ly-49D-associated DAP12 have not been elucidated. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eff19e67426e0e65873c0de4c05f86c
https://doi.org/10.4049/jimmunol.176.11.6615
https://doi.org/10.4049/jimmunol.176.11.6615
Autor:
Stephen K. Anderson, Michael J. Bennett, Lynn S. Taylor, John R. Ortaldo, Andrew P. Makrigiannis, Daniel W. McVicar, Robin Winkler-Pickett
Publikováno v:
The Journal of Immunology. 169:1721-1728
NK cells are implicated in antiviral responses, bone marrow transplantation and tumor immunosurveillance. Their function is controlled, in part, through the Ly49 family of class I binding receptors. Inhibitory Ly49s suppress signaling, while activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff64dc7e2a15875f97873ce40890f55f
https://doi.org/10.4049/jimmunol.169.4.1721
https://doi.org/10.4049/jimmunol.169.4.1721
Publikováno v:
Blood. 96:483-490
CD33 is a myeloid specific member of the sialic acid-binding receptor family and is expressed highly on myeloid progenitor cells but at much lower levels in differentiated cells. Human CD33 has two tyrosine residues in its cytoplasmic domain (Y340 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e537386df0d19d3102bfcb22f28c30
https://doi.org/10.1182/blood.v96.2.483.014k40_483_490
https://doi.org/10.1182/blood.v96.2.483.014k40_483_490
Autor:
Andrew P. Makrigiannis, Pierre Gosselin, Llewellyn H. Mason, Lynn S. Taylor, Daniel W. McVicar, John R. Ortaldo, Stephen K. Anderson
Publikováno v:
The Journal of Immunology. 163:4931-4938
The majority of the known Ly49 family members have been isolated from either C57BL/6 (B6) or BALB/c mice. Interestingly, the anti-Ly49 Ab reactivities observed in 129/J mice are different from those of B6 mice. Furthermore, immunoprecipitation of 129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4e40ec7b706874d16f3132d7f71622
https://doi.org/10.4049/jimmunol.163.9.4931
https://doi.org/10.4049/jimmunol.163.9.4931
Autor:
Lynn S. Taylor, Daniel W. McVicar
Publikováno v:
Blood. 94:1790-1796
Paired immunoglobulin-like receptors (PIR) are expressed on B cells and macrophages and include inhibitory and putative activating receptors referred to as PIR-B and PIR-A, respectively. Although PIR-B’s inhibitory pathway has been described, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f707bc6fd06344b7be6d6d8200fe5d3
https://doi.org/10.1182/blood.v94.5.1790
https://doi.org/10.1182/blood.v94.5.1790
Autor:
John R. Ortaldo, Stephen K. Anderson, Llewellyn H. Mason, Paul A. Linnemeyer, Jami Willette-Brown, Lynn S. Taylor, Robert L. Geahlen, Anwar I. Mikhael, Daniel W. McVicar, William E. Seaman, Pierre Gosselin, Mary C. Nakamura
Publikováno v:
Journal of Biological Chemistry. 273:32934-32942
The murine Ly49 family contains nine genes in two subgroups: the inhibitory receptors (Ly49A, B, C, E, F, G2, and I) and the noninhibitory receptors (Ly49D and H). Unlike their inhibitory counterparts, Ly49D and H do not contain immunoreceptor tyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08be12eec850d9778773534a89181a85
https://doi.org/10.1074/jbc.273.49.32934
https://doi.org/10.1074/jbc.273.49.32934
Autor:
Igor Espinoza-Delgado, Maria Carla Bosco, Sandra Rottschafer, Dan L. Longo, Lynn S. Taylor, John R. Ortaldo
Publikováno v:
Blood. 89:3402-3411
The antineoplastic agent bryostatin-1 (bryo-1) possesses powerful immunomodulatory properties and can function as a biological response modifier in vivo. However, there is currently little information regarding the effects of bryo-1 on cells of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f51cfe26e276c64405a8e59506c8b16
https://doi.org/10.1182/blood.v89.9.3402
https://doi.org/10.1182/blood.v89.9.3402
Autor:
Jih-Jing Lin, Stephen K. Anderson, Giovanni Melillo, Jonathan D. Willis, Robert L. White, George W. Cox, Lynn S. Taylor
Publikováno v:
Journal of Biological Chemistry. 271:25515-25523
Simple tandem repeats of the trinucleotide sequence CAG encode homopolymeric stretches of glutamine. Although polyglutamine has been identified in diverse proteins, it is present predominantly in transcription factors. We observed that oncogene-immor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5939c7ce120a94952a6ef65464391b3
https://doi.org/10.1074/jbc.271.41.25515
https://doi.org/10.1074/jbc.271.41.25515
Publikováno v:
The Journal of Experimental Medicine
Picolinic acid, a catabolite of L-tryptophan, activates the transcription of the inducible nitric oxide synthase gene (iNOS) in IFN-gamma-treated murine macrophages. We performed functional studies on the 5' flanking region of the iNOS gene linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bea77c4fb6d4f821e442daa7357afe
https://doi.org/10.1084/jem.182.6.1683
https://doi.org/10.1084/jem.182.6.1683
Autor:
Mark Creighton-Gutteridge, Luigi Varesio, Annamaria Rapisarda, Alan D. Brooks, Zenghui Mi, Giovanni Melillo, Lynn S. Taylor
Publikováno v:
Cell cycle (Georgetown, Tex.). 7(2)
Hypoxia Inducible Factor-1 (HIF-1) is activated by a variety of stimuli, including inflammatory mediators. In this report we investigated the role that bacterial lipopolysaccharide (LPS) and hypoxia play in the regulation of HIF-1-dependent gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76339624fdc3c7b5cf68e79fb2d05e5b
https://pubmed.ncbi.nlm.nih.gov/18212534
https://pubmed.ncbi.nlm.nih.gov/18212534